- \n
- Genomics and Proteomics, Parasitology, Protein Expression, Drug discovery<\/li>\n<\/ul>\n<\/div>\n<\/div>\n
[\/vc_column_text][\/vc_column][\/vc_row][vc_row css=”.vc_custom_1535953408795{margin-bottom: 0px !important;padding-top: 0px !important;padding-bottom: 0px !important;}”][vc_column][vc_column_text]<\/p>\n
Research<\/h1>\n
[\/vc_column_text][vc_column_text]<\/p>\n
\n\n- \n
- F<\/strong>inal year Research project<\/strong>Structural and Functional characterization of Setaria digitata novel protein (SdNP). The main goal of the research is to overexpress and purify SdNP for the structural and functional characterization. The SdNP gene cloned into pET45b (+) vector was overexpressed in E.coli BL21 (DE3) and purified by Ni- NTA affinity chromatography based on the presence of 6xHis tag to produce protein with ~90% purity. The purified protein was confirmed by Western Blotting for characterization. This research is mainly focused on identification of specific drugs against deadly disease called \u201cLymphatic Filariasis\u201d.Supervisors: <\/strong>Dr. Gayathri De Silva, Prof. R. S. Dassanayake<\/li>\n<\/ul>\n<\/div>\n<\/div>\n
[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"
[vc_row][vc_column width=”1\/4″][vc_single_image image=”274″ img_size=”large” style=”vc_box_shadow_border”][\/vc_column][vc_column width=”3\/4″][vc_column_text] Temporary Academic Staff Department of Chemistry University of Colombo Colombo 00300 Sri Lanka Email: […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-pagebuilder.php","meta":[],"_links":{"self":[{"href":"https:\/\/www.res.cmb.ac.lk\/chemistry\/btec\/wp-json\/wp\/v2\/pages\/153"}],"collection":[{"href":"https:\/\/www.res.cmb.ac.lk\/chemistry\/btec\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.res.cmb.ac.lk\/chemistry\/btec\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.res.cmb.ac.lk\/chemistry\/btec\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.res.cmb.ac.lk\/chemistry\/btec\/wp-json\/wp\/v2\/comments?post=153"}],"version-history":[{"count":4,"href":"https:\/\/www.res.cmb.ac.lk\/chemistry\/btec\/wp-json\/wp\/v2\/pages\/153\/revisions"}],"predecessor-version":[{"id":278,"href":"https:\/\/www.res.cmb.ac.lk\/chemistry\/btec\/wp-json\/wp\/v2\/pages\/153\/revisions\/278"}],"wp:attachment":[{"href":"https:\/\/www.res.cmb.ac.lk\/chemistry\/btec\/wp-json\/wp\/v2\/media?parent=153"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
- F<\/strong>inal year Research project<\/strong>Structural and Functional characterization of Setaria digitata novel protein (SdNP). The main goal of the research is to overexpress and purify SdNP for the structural and functional characterization. The SdNP gene cloned into pET45b (+) vector was overexpressed in E.coli BL21 (DE3) and purified by Ni- NTA affinity chromatography based on the presence of 6xHis tag to produce protein with ~90% purity. The purified protein was confirmed by Western Blotting for characterization. This research is mainly focused on identification of specific drugs against deadly disease called \u201cLymphatic Filariasis\u201d.Supervisors: <\/strong>Dr. Gayathri De Silva, Prof. R. S. Dassanayake<\/li>\n<\/ul>\n<\/div>\n<\/div>\n