- \n
- Graduate Research\u00a0\u00a0(2008-2014)
Wayne State University, Detroit, MI, USA
Department of Chemistry
Advisor: Professor Tamara L. Hendrickson
Dissertation research: Assembly and function of macromolecular complexes for accurate tRNA aminoacylation in\u00a0Helicobacter pylori.<\/em><\/li>\n- Postdoctoral Research (2015)
University of Michigan, Ann Arbor, MI, USA
Department of Immunology and Microbiology
Research: HLA class I polymorphisms and their influences on immunity<\/li>\n<\/ul>\n<\/div>\n<\/div>\n[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n
\u00a0<\/p>\n
\u00a0<\/p>\n
Research in Progress<\/strong><\/p>\n
- \n
- Functional analyses of SdNP; A protein of unknown function in Setaria digitata<\/em> \u2013 structure, activity, substrate specificity, and drug design<\/li>\n
- Development of High-tech transgenic approaches to control dengue by genetic engineering mosquito vector\u00a0Aedes aegypti<\/em><\/strong><\/li>\n
- Design and development of a \u201cRiboswitch biosensor\u201d for the detection of Fluoride levels in drinking water. The materials including bacterial strains and plasmid constructs were provided by Ronald Breaker, Ph. D., Professor of Molecular, Cellular, and Developmental Biology, Yale University, CT, USA<\/em><\/li>\n
- Effect of CRISPR knockout of PFK1 and PFK2 on Oxygen consumption rate in mammalian cells. The plasmid constructs were provided by Vajira Weerasekara, Ph. D., Research Fellow in Medicine at MGH Cancer Center, Harvard Medical School and Broad Institute of MIT and Harvard, MA, USA<\/em><\/li>\n
- Molecular diagnosis of IRFG gene mutations in a selected group of patients clinically diagnosed with Van Der Woude syndrome. Collaborative research project with Faculty of Medicine, Ragama, Sri Lanka<\/em><\/li>\n
- Determining the genetic basis for thyroid hormone resistance in suspected cases in Sri Lanka. Collaborative research project with Faculty of Medicine, Ragama, Sri Lanka<\/em><\/li>\n
- Normal distribution of Methylenetetrahydrofolate Reductase polymorphisms in Sri Lanka. Collaborative research project with Faculty of Medicine, Ragama, Sri Lanka<\/em><\/li>\n
- Investigating the potential antimicrobial properties of bamboo shoot.<\/li>\n<\/ol>\n\n\n
<\/p>\n","protected":false},"excerpt":{"rendered":"
[vc_row css=”.vc_custom_1535953458083{padding-top: 0px !important;padding-bottom: 0px !important;}”][vc_column][vc_column_text] Research Experience [\/vc_column_text][vc_column_text] Graduate Research\u00a0\u00a0(2008-2014)Wayne State University, Detroit, MI, USADepartment of ChemistryAdvisor: Professor Tamara […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.res.cmb.ac.lk\/chemistry\/gayathri-silva\/wp-json\/wp\/v2\/pages\/18"}],"collection":[{"href":"https:\/\/www.res.cmb.ac.lk\/chemistry\/gayathri-silva\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.res.cmb.ac.lk\/chemistry\/gayathri-silva\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.res.cmb.ac.lk\/chemistry\/gayathri-silva\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.res.cmb.ac.lk\/chemistry\/gayathri-silva\/wp-json\/wp\/v2\/comments?post=18"}],"version-history":[{"count":7,"href":"https:\/\/www.res.cmb.ac.lk\/chemistry\/gayathri-silva\/wp-json\/wp\/v2\/pages\/18\/revisions"}],"predecessor-version":[{"id":64,"href":"https:\/\/www.res.cmb.ac.lk\/chemistry\/gayathri-silva\/wp-json\/wp\/v2\/pages\/18\/revisions\/64"}],"wp:attachment":[{"href":"https:\/\/www.res.cmb.ac.lk\/chemistry\/gayathri-silva\/wp-json\/wp\/v2\/media?parent=18"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
- Development of High-tech transgenic approaches to control dengue by genetic engineering mosquito vector\u00a0Aedes aegypti<\/em><\/strong><\/li>\n
- Postdoctoral Research (2015)