Duplication of the inferior vena cava (IVC) is a rare vascular anomaly of surgical significance. We report the case of a 31-year-old healthy female kidney donor in whom preoperative imaging identified a duplicated IVC. This anomaly was apparent on CT angiography, which allowed meticulous surgical planning. The patient subsequently underwent a left open donor nephrectomy without complications. Intraoperative findings confirmed the duplicated IVC, which was managed successfully by careful dissection and preservation of venous drainage. Both donor and recipient had uneventful recoveries. This case underscores the clinical importance of recognizing a duplicated IVC prior to nephrectomy, as early identification enables appropriate surgical strategy to avoid inadvertent vascular injury and ensures optimal outcomes for transplantation