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Type I interferons as an initiating driver of fibrosis in IPF<\/p><\/div><\/div>\n\t\t
Type I interferons (IFN-I)<\/strong> are a family of cytokines mainly consisting of IFN-\u03b1 and IFN-\u03b2<\/strong>, which play important roles in antiviral immunity and regulation of inflammatory responses. Recent research suggests that, in certain contexts, abnormal or persistent activation of Type I interferon pathways may contribute to the initiation and progression of Idiopathic Pulmonary Fibrosis (IPF)<\/strong>.<\/p>\n\n\t\t<\/div> <\/li> Immune Drivers of Fibrotic Pulmonary Sarcoidosis<\/p><\/div><\/div>\n\t\t Sarcoidosis<\/strong> is a chronic, multisystem inflammatory disease characterized by the formation of non-caseating granulomas<\/strong> in affected organs, most commonly the lungs and lymph nodes.<\/p>\n\n\t\t<\/div> <\/li> Liver Macrophages in the Pathogenesis of Dengue<\/p><\/div><\/div>\n\t\t Dengue is a mosquito-borne viral disease caused by the Dengue virus (DENV)<\/strong>, a member of the Flaviviridae<\/em> family. Although dengue is primarily considered a systemic viral infection, the liver is one of the major target organs<\/strong> involved in disease progression.<\/p>\n\n\t\t<\/div> <\/li> Novel Paradigms in Dengue Pathogenesis \u2013 The Hepato-centric Hypothesis<\/p><\/div><\/div>\n\t\t Dengue is one of the most important neglected tropical diseases (NTDs)<\/strong> caused by the Dengue virus (DENV)<\/strong>, a mosquito-borne flavivirus transmitted mainly by Aedes aegypti<\/strong> and Aedes albopictus<\/strong> mosquitoes.<\/p>\n\n\t\t<\/div> <\/li> Establishing Ultrasound as a Biomarker of Moderate Dengue<\/p><\/div><\/div>\n\t\t Dengue is a major neglected tropical disease (NTD)<\/strong> caused by the Dengue virus (DENV)<\/strong> and transmitted by Aedes<\/em> mosquitoes.<\/p>\n\n\t\t<\/div> <\/li> Repurposing Therapeutics in Neglected Tropical Diseases<\/p><\/div><\/div>\n\t\t Neglected Tropical Diseases (NTDs)<\/strong> are a group of infectious diseases that mainly affect populations living in tropical and subtropical regions, particularly in low- and middle-income countries. These diseases are often associated with:<\/p>\n Application of Single-Cell Immunology in Infectious Diseases<\/p><\/div><\/div>\n\t\t Single-cell immunology<\/strong> is an advanced technology that allows scientists to study the immune system by analysing individual cells rather than large populations of cells<\/strong>.<\/p>\n Traditional immunology methods analyse millions of cells together and provide an average response. However, immune responses are highly complex because different immune cells may behave differently during infection.<\/p>\n\n\t\t<\/div> <\/li> Deciphering the Pathogenesis of Thrombotic Microangiopathy (TMA) in Viper Bites in Sri Lanka \u2013 The Role of Endothelial Dysfunction<\/p><\/div><\/div>\n\t\t Snakebite envenoming is recognized by the World Health Organization (WHO)<\/strong> as a neglected tropical disease (NTD)<\/strong> because it causes significant morbidity and mortality, particularly in tropical and rural communities.<\/p>\n\n\t\t<\/div> <\/li><\/ul>[\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":" [vc_row el_class=”fom-header-row”][vc_column css_animation=”zoomIn”][\/vc_column][\/vc_row][vc_row][vc_column][\/vc_column][\/vc_row]<\/p>\n","protected":false},"author":6,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-pagebuilder.php","meta":{"footnotes":""},"_links":{"self":[{"href":"https:\/\/www.res.cmb.ac.lk\/medicine\/praveen-weeratunga\/wp-json\/wp\/v2\/pages\/20"}],"collection":[{"href":"https:\/\/www.res.cmb.ac.lk\/medicine\/praveen-weeratunga\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.res.cmb.ac.lk\/medicine\/praveen-weeratunga\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.res.cmb.ac.lk\/medicine\/praveen-weeratunga\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.res.cmb.ac.lk\/medicine\/praveen-weeratunga\/wp-json\/wp\/v2\/comments?post=20"}],"version-history":[{"count":5,"href":"https:\/\/www.res.cmb.ac.lk\/medicine\/praveen-weeratunga\/wp-json\/wp\/v2\/pages\/20\/revisions"}],"predecessor-version":[{"id":773,"href":"https:\/\/www.res.cmb.ac.lk\/medicine\/praveen-weeratunga\/wp-json\/wp\/v2\/pages\/20\/revisions\/773"}],"wp:attachment":[{"href":"https:\/\/www.res.cmb.ac.lk\/medicine\/praveen-weeratunga\/wp-json\/wp\/v2\/media?parent=20"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Lung Immunology <\/h3>
Monocyte and Macrophage Biology Across Disease <\/h3>
Neglected Tropical Disease <\/h3>
Neglected Tropical Disease <\/h3>
Neglected Tropical Disease (NTD) <\/h3>
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Neglected Tropical Disease (NTD) <\/h3>
Neglected Tropical Disease (NTD) <\/h3>