Dr. E. P. Meran Keshawa
Publications
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In-vitro screening of a small compound library against a panel of human cancer cell lines.
Abstracts (International)
The Asian Symposium on Medicinal Plants, Spices and other Natural Products (ASOMPS), 2018.
Publication year: 2018
In-vitro screening of a small compound library against a panel of human cancer cell lines
Abstracts (International)
Asian Symposium on Medicinal Plants, Spices and Other Natural Products XVI, 2018.
Publication year: 2018
In-vitro anti-cancer effects of compound A isolated from Vernonia zeylanica on embryonal carcinoma cells (NTERA-2),
Abstracts (International)
The Asian Symposium on Medicinal Plants, Spices and other Natural Products (ASOMPS), 2018
Publication year: 2018
Evaluating the anti-cancer mechanisms mediated by an organic solvent based extract of a polyherbal mixture in lung cancer (NCI-H292) cells.
Abstracts (International)
The Asian Symposium on Medicinal Plants, Spices and other Natural Products (ASOMPS), 2018.
Publication year: 2018
Cytotoxic and Apoptotic Effects of Govaniadine Isolated from Corydalis govaniana Wall. Roots on Human Breast Cancer (MCF-7) Cells.
Research Articles
Sivakumaran N, Samarakoon SR, Adhikari A, Ediriweera MK, Tennekoon KH, Malavige N, Thabrew I, Shrestha RL. Cytotoxic and apoptotic effects of govaniadine isolated from Corydalis govaniana Wall. roots on human breast cancer (MCF-7) Cells. BioMed research international. 2018 Jul 24;2018.
Publication year: 2018
Campnospermenone A, B and C, three new cytotoxic alkyl-hydroxycyclohexenones from Campnosperma zeylanica Thwaites leaves
Research Articles
Ediriweera MK, Jayarathna P, Tennekoon KH, Samarakoon SR, Thabrew I, Karunanayake EH, Adhikari A. Campnospermenone A, B and C, three new cytotoxic alkyl-hydroxycyclohexenones from Campnosperma zeylanica Thwaites leaves. Phytochemistry Letters. 2018 Apr 1;24:114-9.
Publication year: 2018
Protective effects of six selected dietary compounds against leptin-induced proliferation of oestrogen receptor positive (MCF-7) breast cancer cells.
Research Articles
Ediriweera MK, Tennekoon KH, Samarakoon SR, Thabrew I, De Silva ED. Protective effects of six selected dietary compounds against leptin-induced proliferation of oestrogen receptor positive (MCF-7) breast cancer cells. Medicines. 2017 Sep;4(3):56.
Publication year: 2017
Isolation of a new resorcinolic lipid from Mangifera zeylanica Hook. f. bark and its cytotoxic and apoptotic potential.
Research Articles
Ediriweera MK, Tennekoon KH, Samarakoon SR, Adhikari A, Thabrew I, De Silva ED. Isolation of a new resorcinolic lipid from Mangifera zeylanica Hook. f. bark and its cytotoxic and apoptotic potential. Biomedicine & Pharmacotherapy. 2017 May 1;89:194-200.
Publication year: 2017
Induction of Apoptosis in MCF‐7 Breast Cancer Cells by Sri Lankan Endemic Mango (Mangifera zeylanica) Fruit Peel through Oxidative Stress and Analysis of its Phytochemical Constituents.
Research Articles
Ediriweera MK, Tennekoon KH, Samarakoon SR, Thabrew I, De Silva ED. Induction of apoptosis in MCF‐7 breast cancer cells by Sri Lankan Endemic Mango (Mangifera zeylanica) fruit peel through oxidative stress and analysis of its phytochemical constituents. Journal of Food Biochemistry. 2017 Feb;41(1):e12294.
Publication year: 2017
In vitro anticancer effect of gedunin on human teratocarcinomal (NTERA-2) cancer stem-like cells
Research Articles
Tharmarajah L, Samarakoon SR, Ediriweera MK, Piyathilaka P, Tennekoon KH, Senathilake KS, Rajagopalan U, Galhena PB, Thabrew I. In vitro anticancer effect of gedunin on human teratocarcinomal (NTERA-2) cancer stem-like cells. BioMed research international. 2017 Jun 7;2017.
Publication year: 2017
Chitosan Nano-encapsulation Enhances Gedunin Cytotoxicity A gainst Human Non-small-cell Lung Cancer (NCI-H292) Cell Line.
Research Articles
Nwokwu CD, Samarakoon SR, Karunaratne DN, Katuvawila NP, Ediriweera MK, Tennekoon KH. Chitosan Nano-encapsulation Enhances Gedunin Cytotoxicity A gainst Human Non-small-cell Lung Cancer (NCI-H292) Cell Line. Drug Delivery Letters. 2017 Dec 1;7(3):219-26.
Publication year: 2017
Anti-hepatocarcinogenic and anti-oxidant effects of mangrove plant Scyphiphora hydrophyllacea.
Research Articles
Samarakoon SR, Shanmuganathan C, Ediriweera MK, Piyathilaka P, Tennekoon KH, Thabrew I, Galhena P, De Silva ED. Anti-hepatocarcinogenic and anti-oxidant effects of mangrove plant Scyphiphora hydrophyllacea. Pharmacognosy magazine. 2017 Jan;13(Suppl 1):S76.
Publication year: 2017
A Study on Cytotoxic and Apoptotic Potential of a Triterpenoid Saponin (3-O--L-Arabinosyl Oleanolic Acid) Isolated from Schumacheria castaneifolia Vahl in Human Non-Small-Cell Lung Cancer (NCI-H292) Cells.
Research Articles
Samarakoon SR, Ediriweera MK, Nwokwu CD, Bandara CJ, Tennekoon KH, Piyathilaka P, Karunaratne D, Karunaratne V. A Study on Cytotoxic and Apoptotic Potential of a Triterpenoid Saponin (3-O--L-Arabinosyl Oleanolic Acid) Isolated from Schumacheria castaneifolia Vahl in Human Non-Small-Cell Lung Cancer (NCI-H292) Cells. BioMed research international. 2017;2017.
Publication year: 2017
A Review on Ethnopharmacological Applications, Pharmacological Activities, and Bioactive Compounds of Mangifera indica (Mango).
Research Articles
Ediriweera MK, Tennekoon KH, Samarakoon SR. A review on ethnopharmacological applications, pharmacological activities, and bioactive compounds of Mangifera indica (Mango). Evidence-Based Complementary and Alternative Medicine. 2017 Dec 31;2017.
Publication year: 2017
Screening of selected natural compounds for anti-cancer activity regulated via induced differentiation on cancer stem cells (NT2).
Abstracts (Local)
8th Annual scientific sessions, May 2016. Institute of Biochemistry, Molecular Biology and Biotechnology (IBMBB), University of Colombo, Sri Lanka.
Publication year: 2016
Screening of Fifteen Mangrove Plants Found in Sri Lanka for in-vitro Cytotoxic Properties on Breast (MCF-7) and Hepatocellular Carcinoma (HepG2) Cells
Research Articles
Samarakoon SR, Shanmuganathan C, Ediriweera MK, Piyathilaka P, Tennekoon KH, Thabrew I. Screening of fifteen mangrove plants found in Sri Lanka for in-vitro cytotoxic properties on breast (MCF-7) and hepatocellular carcinoma (HepG2) cells. European Journal of Medicinal Plants. 2016 May 3:1-1.
Publication year: 2016
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CD/DVD
Publication year: 2016
New halogenated constituents from Mangifera zeylanica Hook. f. and their potential anti-cancer effects in breast and ovarian cancer cells
Research Articles
Ediriweera MK, Tennekoon KH, Adhikari A, Samarakoon SR, Thabrew I, De Silva ED. New halogenated constituents from Mangifera zeylanica Hook. f. and their potential anti-cancer effects in breast and ovarian cancer cells. Journal of ethnopharmacology. 2016 Aug 2;189:165-74.
Publication year: 2016
Isolation of Hopenone-I from the Leaves of Mangrove Plant Scyphiphora hydrophyllacea and Its Cytotoxic Properties.
Research Articles
Samarakoon SR, Fernando N, Ediriweera MK, Adhikari A, Wijayabandara L, de Silva ED, Tennekoon KH. Isolation of hopenone-I from the leaves of mangrove plant Scyphiphora hydrophyllacea and its cytotoxic properties. Journal of Pharmaceutical Research International. 2016:1-6.
Publication year: 2016
Induction of apoptosis in response to improved gedunin by liposomal nano-encapsulation in small-cell lung cancer (NCI-H292) cell line.
Abstracts (Local)
8th Annual scientific sessions, May 2016. Institute of Biochemistry, Molecular Biology and Biotechnology (IBMBB), University of Colombo, Sri Lanka.
Publication year: 2016
In vitro cytotoxic and antioxidant activity of leaf extracts of mangrove plant, Phoenix paludosa Roxb
Research Articles
Samarakoon SR, Shanmuganathan C, Ediriweera MK, Tennekoon KH, Piyathilaka P, Thabrew I, de Silva ED. In vitro cytotoxic and antioxidant activity of leaf extracts of mangrove plant, Phoenix paludosa Roxb. Tropical Journal of Pharmaceutical Research. 2016 May 11;15(1):127-32.
Publication year: 2016
Cytotoxic, antioxidant and apoptotic effects of twenty sri lankan endemic plants in breast cancer cells.
Research Articles
Jayarathna PP, Tennekoon KH, Samarakoon SR, Thabrew I, Karunanayake EH, de Silva ED, Ediriweera MK. Cytotoxic, antioxidant and apoptotic effects of twenty Sri Lankan endemic plants in breast cancer cells. European Journal of Medicinal Plants. 2016 May 18:1-5.
Publication year: 2016
Cytotoxic potential of new compounds isolated from Mangifera zeylanica on breast (MCF-7 and MDA-MB-231) and ovarian (SKOV-3) cancer cells.
Abstracts (Local)
8th Annual scientific sessions, May 2016. Institute of Biochemistry, Molecular Biology and Biotechnology (IBMBB), University of Colombo, Sri Lanka.
Publication year: 2016
Cytotoxic and apoptotic effects of the bark of two common mango (Mangifera indica) varieties from sri lanka on breast and ovarian cancer cells.
Research Articles
Ediriweera MK, Tennekoon KH, Samarakoon SR, Thabrew I, De Silva ED. Cytotoxic and apoptotic effects of the bark of two common mango (Mangifera indica) varieties from Sri Lanka on breast and ovarian cancer cells. Journal of Pharmaceutical Research International. 2016 Jan 25:1-7.
Publication year: 2016
Anti-proliferative and proapoptotic effects of govaniadine in human breast cancer (MCF-7) cells.
Abstracts (Local)
8th Annual scientific sessions, May 2016. Institute of Biochemistry, Molecular Biology and Biotechnology (IBMBB), University of Colombo, Sri Lanka.
Publication year: 2016
A study of the potential anticancer activity of Mangifera zeylanica bark: Evaluation of cytotoxic and apoptotic effects of the hexane extract and bioassay-guided fractionation to identify phytochemical constituents
Research Articles
Ediriweera MK, Tennekoon KH, Samarakoon SR, Thabrew I, Dilip De Silva E. A study of the potential anticancer activity of Mangifera zeylanica bark: Evaluation of cytotoxic and apoptotic effects of the hexane extract and bioassay-guided fractionation to identify phytochemical constituents. Oncology letters. 2016 Feb 1;11(2):1335-44.
Publication year: 2016
Isolation of quercetin from the bark of Mangifera zeylanica and its cytotoxicity against MCF-7 breast cancer cells.
Abstracts (Local)
7th Annual Scientific Sessions, May 2015. Institute of Biochemistry, Molecular Biology and Biotechnology (IBMBB), University of Colombo, Sri Lanka.
Publication year: 2015
Cytotoxic effects of hopenone-I isolated from leaves of the mangrove plant Scyphiphora hydrophyllacea on breast cancer (MCF-7) cells.
Abstracts (Local)
7th Annual Scientific Sessions, May 2015. Institute of Biochemistry, Molecular Biology and Biotechnology (IBMBB), University of Colombo, Sri Lanka.
Publication year: 2015
Cytotoxic effects of hopenone-I isolated from leaves of the mangrove plant Scyphiphora hydrophyllacea on breast cancer (MCF-7) cells.
Abstracts (Local)
7th Annual Scientific Sessions, May 2015. Institute of Biochemistry, Molecular Biology and Biotechnology (IBMBB), University of Colombo, Sri Lanka.
Publication year: 2015