Dr. Narmada Fernando
Institute of Biochemistry, Molecular Biology and Biotechnology (IBMBB)
Publications
Establishment of methods for retrieving Leptospira organisms/ antigens in urine and blood
Weerasinghe HS, Fernando N, Rajapakse S, Premawansa S, Handunnetti SM, Establishment of methods for retrieving Leptospira organisms/ antigens in urine and blood, Proceedings of the 9th Annual Scientific Sessions, IBMBB, University of Colombo, 2017, pp 31.
Do human serum factors protect endothelial cells against pathogenic Leptospira?
Narmada Fernando, Shiroma Handunnetti, Lilani Karunanayake, Sunil Premawansa, Senaka Rajapakse. Do human serum factors protect endothelial cells against pathogenic Leptospira?, 10th International Leptospirosis Society Scientific Meeting, Palmerstone, New Zealand, 27th Nov-1stDec 2017, p 245
Assessment of RNS and ROS production by healthy phagocytic cells stimulated with leptospires in vitro
Wickramasinghe Arachchi SM, Edward D, Fernando N, Hadunnetti SM, Rajapakse S. Assessment of RNS and ROS production by healthy phagocytic cells stimulated with leptospires in vitro. Proceedings of the 9th Annual Scientific Sessions, IBMBB, University of Colombo, 2017, pp 30.
Antibiotic Susceptibility of Clinical Isolates of Human Leptospirosis in Sri Lanka
Karunanayake Lilani, Rajapaksha RRN, Perera KCR, Fernando N, Niloofa R, Handunnetti S, Premawansa S, Rajapakse S. Antibiotic Susceptibility of Clinical Isolates of Human Leptospirosis in Sri Lanka, 10th International Leptospirosis Society Scientific Meeting, Palmerstone, New Zealand, 27th Nov-1stDec 2017, pp 203
Altered Reactive Nitrogen Species production, NF-κB expression in phagocytes and severity of severe leptospirosis infections
Shiroma Handunnetti, Narmada Fernando, Sanjika Milhani, Daniya Edward, Lilani Karunanayake, Sunil Premawansa, Senaka Rajapakse. Altered Reactive Nitrogen Species production, NF-κB expression in phagocytes and severity of severe leptospirosis infections, 10th International Leptospirosis Society Scientific Meeting, Palmerstone, New Zealand, 27th Nov-1stDec 2017, pp 247
Protein Carbonyl as a Biomarker of Oxidative Stress in Severe Leptospirosis, and Its Usefulness in Differentiating Leptospirosis from Dengue Infections
Narmada Fernando, Shalini Wickremesinghe, Roshan Niloofa, Chaturaka Rodrigo, Lilani Karunanayake, H. Janaka de Silva, A. R. Wickremesinghe, Sunil Premawansa, Senaka Rajapakse, Shiroma M. Handunnetti (2016) Protein Carbonyl as a Biomarker of Oxidative Stress in Severe Leptospirosis, and Its Usefulness in Differentiating Leptospirosis from Dengue Infections. PLoS ONE 11(6): e0156085. doi:10.1371/journal. pone.0156085
Protein Carbonyl as a Biomarker of Oxidative Stress for Differentiating Critical Phase Dengue Infections from Severe Leptospirosis
Narmada Fernando, Shalini Wickremesinghe, Roshan Niloofa, Chaturaka Rodrigo, Lilani Karunanayake, H. Janaka de Silva, A. R. Wickremesinghe, Sunil Premawansa, Senaka Rajapakse, Shiroma M. Handunnetti, Protein Carbonyl as a Biomarker of Oxidative Stress for Differentiating Critical Phase Dengue Infections from Severe Leptospirosis, NSF Research Summit, 2016, Abstract no. DE 01.
Effects of pathogenic Leptospira on functions and viability of vascular endothelial cells and kidney epithelial cells
Fernando N., Handunnetti SM., Rajapakse S., de Silva HJ and Premawansa S. Effects of pathogenic Leptospira on functions and viability of vascular endothelial cells and kidney epithelial cells. Proceedings of the 8th Annual Scientific Sessions, IBMBB, University of Colombo, 2016, pp 20.
A diagnostic scoring model for leptospirosis in resource limited settings - A prospective study
Senaka Rajapakse, Praveen Weeratunga, Roshan Niloofa, Narmada Fernando, Nipun Lakshitha de Silva, Chaturaka Rodrigo, Sachith Maduranga, Nuwanthi Nandasiri, Sunil Premawansa, Lilani Karunanayake, H. Janaka de Silva, Shiroma Handunnetti (2016) A diagnostic scoring model for leptospirosis in resource limited settings – A prospective study. PLOS Neglected Tropical Diseases. 10 (6): e0004513. doi:10.1371/journal.pntd.0004513
Narmada Fernando, Jayamini Harasgama, Roshan Niloofa, Lilani Karunanayake, Janaka H de Silva, Senaka Rajapakse, Sunil Premawansa, Shiroma Handunnetti. Vascular endothelial cell damage by pathogenic Leptospira. iPURSE 2015, University of Peradeniya; pp 339
The role of neutrophils in the interaction between pathogenic Leptospira and vascular endothelial cells
Shiroma Handunnetti, Narmada Fernando, Senaka Rajapakse, H Janaka de Silva, Sunil Premawansa, The role of neutrophils in the interaction between pathogenic Leptospira and vascular endothelial cells, 9th International Leptospirosis Society Scientific Meeting 2015, Semarang, Indonesia; pp 101
Superoxide production by differentiated HL-60 cells interacted with Leptospira
Narmada Fernando, Roshan Niloofa, Lilani Karunanayake, H Janaka de Silva, Sunil Premawansa, Senaka Rajapakse, Shiroma Handunnetti. Superoxide production by differentiated HL-60 cells interacted with Leptospira. 2nd ELS meeting on Leptospirosis and other rodent borne haemorrhagic fevers.16-18th April 2015; 58
Role of antibody response in disease severity of Leptospirosis
Roshan Niloofa, Narmada Fernando, Lilani Karunanayake, H Janaka de Silva, Sunil Premawansa, Senaka Rajapakse, Shiroma Handunnetti, Role of antibody response in disease severity of Leptospirosis, Proceedings of the 7th Annual Scientific Sessions of the IBMBB, University of Colombo, 2015, Abstract no.11, pp 21.
Pathogenic Leptospira spp induce higher superoxide anion production by HL 60-derived neutrophils
Fernando TRGN, Niloofa MJR, de Silva HJ, Rajapakse S, Premawansa S, Handunnetti SM, Pathogenic Leptospira spp induce higher superoxide anion production by HL 60-derived neutrophils, 71st Annual Sessions of the Sri Lanka Association for the Advancement of Science, 2015, pp 52.
linical and laboratory associations of severity in a Sri Lankan cohort of patients with serologically confirmed Leptospirosis – a prospective study
Rajapakse S, Weeratunga PN, Rodrigo C, Sriharan S, Niloofa MJR, Fernando N, de Silva HJ, Karunanayake L, Premawansa S, Handunnetti S. Clinical and laboratory associations of severity in a Sri Lankan cohort of patients with serologically confirmed Leptospirosis – a prospective study. SLMA 128th Anniversary International Medical Congress; 2015; pp119
Leptospirosis severity association with the humoral immune response
Roshan Niloofa, Narmada Fernando, Lilani Karunanayake, H Janaka de Silva, Sunil Premawansa, Senaka Rajapakse, Shiroma Handunnetti. Leptospirosis severity association with the humoral immune response. 2nd ELS meeting on Leptospirosis and other rodent borne haemorrhagic fevers.16-18th April 2015;56
Laboratory diagnosis of leptospirosis: Choice of tests at different stages of the infection
Roshan Niloofa, Narmada Fernando, Lilani Karunanayake, H Janaka de Silva, Sunil Premawansa, Senaka Rajapakse, Shiroma Handunnetti, Laboratory diagnosis of leptospirosis: Choice of tests at different stages of the infection, Proceedings of the 48th Annual Academic sessions of Ceylon College of Physicians, 2015, pp 08.
Inflammatory cytokine responses in Sri Lankan patients with leptospirosis and the effect of antibiotic treatment
Narmada Fernando, Rajiva De Silva, Shiroma Handunnetti, Lilani Karunanayake, H Janaka de Silva, Senaka Rajapakse, Sunil Premawansa, Inflammatory cytokine responses in Sri Lankan patients with leptospirosis and the effect of antibiotic treatment, International Leptospirosis Society 2015, Indonesia; pp 42
Do antibodies play a role in ROS production by HL 60-derived neutrophils against Leptospira?
Narmada Fernando, Roshan Niloofa, Lilani Karunanayake, H Janaka de Silva, Sunil Premawansa, Senaka Rajapakse, Shiroma Handunnetti, Do antibodies play a role in ROS production by HL 60-derived neutrophils against Leptospira?, Proceedings of the 7th Annual Scientific Sessions of the IBMBB, University of Colombo, 2015, Abstract no.08, pp 18.
Differentiation of severe leptospirosis from critical phase dengue infections
Narmada Fernando, Roshan Niloofa, Lilani Karunanayake, H Janaka de Silva, Sunil Premawansa, Senaka Rajapakse, Shiroma Handunnetti. Differentiation of severe leptospirosis from critical phase dengue infections. 2nd ELS meeting on Leptospirosis and other rodent borne haemorrhagic fevers.16-18th April 2015; 14
Diagnosis of Leptospirosis: Comparison between Microscopic Agglutination Test, IgM-ELISA and IgM Rapid Immunochromatography Test
Roshan Niloofa, Narmada Fernando, Nipun Lakshitha de Silva, Lilani Karunanayake, Hasith Wickremesinghe, Nandana Dikmadugoda, Gayani Premawansa, Rajitha Wikramasinghe, H Janaka de Silva, Sunil Premawansa, Senaka Rajapakse, Shiroma Handunnetti. (2015) Diagnosis of Leptospirosis: Comparison between Microscopic Agglutination Test, IgM-ELISA and IgM Rapid Immunochromatography Test. PLoS ONE, 18;10 (6)
Clinico-epidemiological characteristics, treatment and outcomes of patients with confirmed Leptospirosis in a Sri Lankan healthcare setting
Rajapakse S, Weeratunga PN, Rodrigo C, Sriharan S, Niloofa MJR, Fernando N, de Silva HJ, Karunanayake L, Premawansa S, Handunnetti S. Clinico-epidemiological characteristics, treatment and outcomes of patients with confirmed Leptospirosis in a Sri Lankan healthcare setting. SLMA 128th Anniversary International Medical Congress; 2015; pp120
Clinical and laboratory associations of severity in a Sri Lankan cohort of patients with serologically confirmed leptospirosis – A prospective study
Senaka Rajapakse, Praveen Weeratunga, M.J. Roshan Niloofa, Narmada Fernando, Chathuraka Rodrigo, Sachith Maduranga, Nipun Lakshitha Fernando, H. Janaka De Silva, Lilani Karunanayake, Shiroma Handunnetti (2015) Clinical and laboratory associations of severity in a Sri Lankan cohort of patients with serologically confirmed leptospirosis – A prospective study. Transactions of Royal Society of Tropical Medicine and Hygiene, 109 (11): 710-716.
A diagnostic model for Leptospirosis for use in resource limited settings
Rajapakse S, Weeratunga PN, Rodrigo C, Sriharan S, Niloofa MJR, Fernando N, de Silva HJ, Karunanayake L, Premawansa S, Handunnetti S. A diagnostic model for Leptospirosis for use in resource limited settings. SLMA 128th Anniversary International Medical Congress; 2015; pp120
Fernando TRGN, Niloofa MJR, Maduranga S, Rodrigo C, Karunanayake L, De Silva HJ, Rajapakse S, Premawansa S, Handunnetti SM, Oxidative damage of lipids and proteins in Leptospirosis, 2nd International Conference on Frontiers in Molecular Life Scienecs, Institute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo; 2014; pp 38
High serum lipid peroxide and low anti-oxidant capacity in leptospirosis
Narmada Fernando, Niloofa MJR, Sachith Maduranga, Lilani Karunanayake, Janaka De Silva, Senaka Rajapakse, Sunil Premawansa, Shiroma Handunnetti, High serum lipid peroxide and low anti-oxidant capacity in leptospirosis, One Health International Conference, University of Peradeniya; 2014; pp 20
Evaluation of leptospirosis diagnostic tests: microscopic agglutination test, IgM based ELISA and Immunocromatography
Niloofa MJR, Fernando TRGN, De Silve NL, Karunanayake L, Wickremesinghe H, Dikmadugoda N, Premawansa G, Wickremesinghe AR, De Silva HJ, Premawansa S, Rajapakse S, Handunetti SM, Evaluation of leptospirosis diagnostic tests: microscopic agglutination test, IgM based ELISA and Immunocromatography, 2nd International Conference on Frontiers in Molecular Life Scienecs, Institute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo; 2014; pp 38
Evaluation of Leptospirosis diagnostic tests: microscopic agglutination test, IgM based ELISA and immunochromatography test
Niloofa MJR, Fernando TRGN, De Silva NL, Karunanayake L, De Silva HJ, Premawansa S, Rajapakse S, Handunnetti SM . Evaluation of Leptospirosis diagnostic tests: microscopic agglutination test, IgM based ELISA and immunochromatography test. Immunology Day Symposium 2014, Allergy and Immunology Society of Sri Lanka, 26th February, 2014.
Changes in full blood count parameters in leptospirosis: a prospective study
Nipun Lakshitha De Silva, MJR Niloofa, Narmada Fernando, Lilani Karunanayake, Chaturaka Rodrigo, H Janaka de Silva, Sunil Premawansa, Shiroma M Handunnetti and Senaka Rajapakse, (2014) Changes in full blood count parameters in leptospirosis: a prospective study, International Archives of Medicine, 7:31
Narmada Fernando, S Wickramasinghe, L Karunanayake, HJ De Silva, S Premawansa, S Rajapakse, SM Handunnetti, Biomarkers of oxidative stress in severe leptospirosis, Proceedings of the 7th Biennial Sessions of the Allergy and Immunology Society of Sri lanka; 2014; pp 34.