Study on identification of lipopolysaccharide types in Burkholderia pseudomallei strains isolated from patients in Sri Lanka

Poster Presentation
NM Kiyas, E Corea, N Fernando, SM Handunnetti
Publication year: 2021

NM Kiyas, E Corea, N Fernando, SM Handunnetti, Study on identification of lipopolysaccharide types in Burkholderia pseudomallei strains isolated from patients in Sri Lanka. Proceedings of the 9 th Biennial Scientific Sessions, Allergy and Immunology Society of Sri Lanka, pp321.

Ion transport modulators differentially modulate inflammatory responses in THP-1-Derived Macrophages

Publications in peer reviewed Journals
Mitini-Nkhoma SC, Fernando N, Ishaka GKD, Handunnetti SM, Pathirana SL
Publication year: 2021

Mitini-Nkhoma SC, Fernando N, Ishaka GKD, Handunnetti SM, Pathirana SL.  Ion transport modulators differentially modulate inflammatory responses in THP-1-Derived Macrophages. Journal of Immunology Research. Volume 2021 |Article ID 8832586 | https://doi.org /10.1155/2021/8832586

Identification of immunogens of biflexa serovar Patoc

Oral Presentations
P D Gangani, W G K Anuradha, N Fernando, M G Tammitiyagodage, L Karunanayake, S Rajapakse, S Premawansa, S M Handunnetti
Publication year: 2021

P D Gangani, W G K Anuradha, N Fernando, M G Tammitiyagodage, L Karunanayake, S Rajapakse, S Premawansa, S M Handunnetti, Identification of immunogens of biflexa serovar Patoc, Proceedings of the 9 th Biennial Scientific Sessions, Allergy and Immunology Society of Sri Lanka, pp17

Effect of pharmacological compounds and plant extracts on dengue virus induced rat basophil degranulation

Oral Presentations
K.V.C Wijegunarathna, N. Fernando, S.M Hadunnetti, S. Premawansa
Publication year: 2021

K.V.C Wijegunarathna, N. Fernando, S.M Hadunnetti, S. Premawansa, Effect of pharmacological compounds and plant extracts on dengue virus induced rat basophil degranulation, Proceedings of the 9 th Biennial Scientific Sessions, Allergy and Immunology Society of Sri Lanka, pp23

Comparison of antigen profiles of pathogenic serovars of interrogans and non-pathogenic L. biflexa

Poster Presentation
WGK Anuradha, PD Gangani, L Karunanayake, N Fernando, SM Handunnetti
Publication year: 2021

WGK Anuradha, PD Gangani, L Karunanayake, N Fernando, SM Handunnetti, Comparison of antigen profiles of pathogenic serovars of interrogans and non-pathogenic L. biflexa, Proceedings of the 9 th Biennial Scientific Sessions, Allergy and Immunology Society of Sri Lanka, pp27

Changes in peritoneal lymphocyte subpopulations and antibody response in rats immunized with purified LPS of pathogenic and non-pathogenic Leptospira spp.

Poster Presentation
DDWCK Dissanayake, SM Handunnetti, N Fernando, D Gangani, RD Silva, S Premawansa
Publication year: 2021

DDWCK Dissanayake, SM Handunnetti, N Fernando, D Gangani, RD Silva, S Premawansa, Changes in peritoneal lymphocyte subpopulations and antibody response in rats immunized with purified LPS of pathogenic and non-pathogenic Leptospira spp., Proceedings of the 9 th Biennial Scientific Sessions, Allergy and Immunology Society of Sri Lanka, pp30

Anti-inflammatory effect of leaves of Vernonia zeylanica in lipopolysaccharide-stimulated RAW 264.7 macrophages and carrageenan-induced rat paw-edema model

Publications in peer reviewed Journals
Dilani Rukshala, E. Dilip de Silva, B.V. Loshini R. Ranaweera, Narmada Fernando, Shiroma M. Handunnetti
Publication year: 2021

Dilani Rukshala, E. Dilip de Silva, B.V. Loshini R. Ranaweera, Narmada Fernando, Shiroma M. Handunnetti, Anti-inflammatory effect of leaves of Vernonia zeylanica in lipopolysaccharide-stimulated RAW 264.7 macrophages and carrageenan-induced rat paw-edema model, Journal of Ethnopharmacology, 2021, https://doi.org/10.1016/j.jep.2021.114030

The impact of propranolol on nitric oxide and total antioxidant capacity in patients with resistant hypertension—evidence from the APPROPRIATE trial

Publications in peer reviewed Journals
N. Ranasinghe, N. Fernando, S. Handunnetti, P. N. Weeratunga, P. Katulanda, S. Rajapakse, P. Galappatthy and G. R. Constantine
Publication year: 2020

N. Ranasinghe, N. Fernando, S. Handunnetti, P. N. Weeratunga, P. Katulanda, S. Rajapakse, P. Galappatthy and G. R. Constantine. The impact of propranolol on nitric oxide and total antioxidant capacity in patients with resistant hypertension—evidence from the APPROPRIATE trial. BMC Research Notes, 2020; 13:228, https://doi.org/10.1186/s13104-020-05067-5

Seroprevalence of leptospirosis in an endemic mixed urban and semi-urban setting – A community-based study in the district of Colombo, Sri Lanka

Publications in peer reviewed Journals
Senaka Rajapakse, Praveen N. Weeratunga, Krishan Balaji, Kyra C. Ramchandani, Udani Savbhagya de Silva, Dinesh Gunarathne, Pasindu P.B. Wijerathne, Narmada Fernando, Shiroma M. Handunetti, Sumadhya Deepika Fernando
Publication year: 2020

Senaka Rajapakse, Praveen N. Weeratunga, Krishan Balaji, Kyra C. Ramchandani, Udani Savbhagya de Silva, Dinesh Gunarathne, Pasindu P.B. Wijerathne, Narmada Fernando, Shiroma M. Handunetti, Sumadhya Deepika Fernando, Seroprevalence of leptospirosis in an endemic mixed urban and semi-urban setting – A community-based study in the district of Colombo, Sri Lanka, PLOS Neglected Tropical Diseases. 2020 In Press. (EMID:b92a38933274321e)

Preliminary study to detect mutations in UL97 gene in suspected gancyclovir resistant CMV patients' samples

Oral Presentations
Thambyrajah JT, Jayamaha CJS, Ratnayake AKDVY, Handunnetti S, Fernando N
Publication year: 2020

Thambyrajah JT, Jayamaha CJS, Ratnayake AKDVY, Handunnetti S, Fernando N, Preliminary study to detect mutations in UL97 gene in suspected gancyclovir resistant CMV patients’ samples, presented to a diagnostic laboratory in Sri Lanka, 29th Annual Scientific Sessions, Collage of Microbiologists, Sri Lanka

Ion Transport Modulators as Antimycobacterial Agents

Publications in peer reviewed Journals
Steven C. Mitini-Nkhoma, Narmada Fernando, G. K. D. Ishaka, Shiroma M. Handunnetti, and Sisira L. Pathirana
Publication year: 2020

 

Steven C. Mitini-Nkhoma, Narmada Fernando, G. K. D. Ishaka, Shiroma M. Handunnetti, and Sisira L. Pathirana, Ion Transport Modulators as Antimycobacterial Agents, Tuberculosis Research and Treatment, Volume 2020, Article ID 3767915, 7 pages, https://doi.org/10.1155/2020/3767915

n vitro study of IgE independent basophil degranulation due to selected food items

Oral Presentations
Wijerathna DMCK, Handunnetti SM, Fernando N, Premawansa S
Publication year: 2019

Wijerathna DMCK, Handunnetti SM, Fernando N, Premawansa S, In vitro study of IgE independent basophil degranulation due to selected food items, Proceedings of the 11th Annual Scientific Sessions, IBMBB, University of Colombo, 2019, pp 21

Ion pump and ion channel modulators as anti-mycobacterial agents

Poster Presentation
Mitini-Nkhoma SC, Pathirana PPSL, Fernando N, Ishaka D, Handunnetti SM
Publication year: 2019

Mitini-Nkhoma SC, Pathirana PPSL, Fernando N, Ishaka D, Handunnetti SM, Ion pump and ion channel modulators as anti-mycobacterial agents, Proceedings of the 11th Annual Scientific Sessions, IBMBB, University of Colombo, 2019, pp 34

In vitro effects of methanol-dichloromethane extract of Vernonia zeylanica and its solvent fractions on human, matured KU 812-derived basophils

Oral Presentations
Ezechukwu HC, Rukshala BAD, Dilini I, Fernando N, Handunnetti SM
Publication year: 2019

Ezechukwu HC, Rukshala BAD, Dilini I, Fernando N, Handunnetti SM, In vitro effects of methanol-dichloromethane extract of Vernonia zeylanica and its solvent fractions on human, matured KU 812-derived basophils, Proceedings of the 11th Annual Scientific Sessions, IBMBB, University of Colombo, 2019, pp 26

Effects of ion pump and ion channel modulators on activation and function THP-1 derived macrophages

Oral Presentations
Mitini-Nkhoma SC, Pathirana PPSL, Fernando N, Handunnetti SM, Ishaka D
Publication year: 2019

Mitini-Nkhoma SC, Pathirana PPSL, Fernando N, Handunnetti SM, Ishaka D, Effects of ion pump and ion channel modulators on activation and function THP-1 derived macrophages, Proceedings of the 11th Annual Scientific Sessions, IBMBB, University of Colombo, 2019, pp 25

Comparison of IgG and IgM responses in rats immunized with two types of antigen preparations of Leptospira biflexa serovar Patoc

Oral Presentations
Gangani PD, Ishaka GKD, Fernando N, Karunanayake L, Rajapakse S, Premawansa S, Handunnetti SM
Publication year: 2019

Gangani PD, Ishaka GKD, Fernando N, Karunanayake L, Rajapakse S, Premawansa S, Handunnetti SM, Comparison of IgG and IgM responses in rats immunized with two types of antigen preparations of Leptospira biflexa serovar Patoc, Proceedings of the 11th Annual Scientific Sessions, IBMBB, University of Colombo, 2019, pp 22

 

A preliminary study on VP1 gene based genotyping of BK virus isolated from kidney transplant patients

Oral Presentations
Ratnayake AKDVY, Jayamaha CJS, Fernando N, Gajanayake T
Publication year: 2019

Ratnayake AKDVY, Jayamaha CJS, Fernando N, Gajanayake T, A preliminary study on VP1 gene based genotyping of BK virus isolated from kidney transplant patients, International Conference on Infectious Diseases and Antimicrobial Resistance, Sri Lanka Collage of Microbiologists, Aug 08th – 11th; pp 14

 

A preliminary study on the roles of oxidative stress and anti-oxidant therapy in resistant hypertension patients in Sri Lanka

Poster Presentation
Ranasinghe RAHN, Fernando N, Handunnetti S, Weeratunga P, Galappatthy P, Constantine GR
Publication year: 2019

Ranasinghe RAHN, Fernando N, Handunnetti S, Weeratunga P, Galappatthy P, Constantine GR, A preliminary study on the roles of oxidative stress and anti-oxidant therapy in resistant hypertension patients in Sri Lanka, Proceedings of the 11th Annual Scientific Sessions, IBMBB, University of Colombo, 2019, pp 35

 

The effect of antimicrobial agents on inflammatory cytokines in acute leptospirosis

Publications in peer reviewed Journals
Narmada Fernando, Rajiva de Silva, Shiroma M Handunnetti, Lilani Karunanayake, Nipun Lakshitha De Silva, H Janaka de Silva, Senaka Rajapakse, Sunil Premawansa
Publication year: 2018

Narmada Fernando, Rajiva de Silva, Shiroma M Handunnetti, Lilani Karunanayake, Nipun Lakshitha De Silva, H Janaka de Silva, Senaka Rajapakse, Sunil Premawansa. The effect of antimicrobial agents on inflammatory cytokines in acute leptospirosis. Antimicrobial Agents and Chemotherapy. May 2018; 62(5) e02312-17. r62:e02312-17.https://doi .org/10.1128/ AAC.02312-17.

Serological prevalence and determination of cutoff levels of Leptospirosis IgM and IgG in relation to Patoc I strain of Leptospira biflexa in a cohort of individuals from a high prevalence region in Sri Lanka

Poster Presentation
Balaji K, Weeratunga  PN,  Ramchandani KC, Wijerathne PBP, Sam G, Fernando N, Handunnetti SM, Fernando SD,  Rajapakse S
Publication year: 2018

Balaji K, Weeratunga  PN,  Ramchandani KC, Wijerathne PBP, Sam G, Fernando N,
Handunnetti SM, Fernando SD,  Rajapakse S, Serological prevalence and determination of cutoff levels of Leptospirosis IgM and IgG in relation to Patoc I strain of Leptospira biflexa in a cohort of individuals from a high prevalence region in Sri Lanka, Proceedings of the 10th Annual Scientific Sessions, IBMBB, University of Colombo, 2018, pp

Microscopic Agglutination Titre (MAT) for leptospirosis and associations in a population cohort in a high endemic region in Sri Lanka

Poster Presentation
Balaji K, Weeratunga  PN,  Ramchandani KC, Wijerathne PBP, Sam G, Fernando N, Handunnetti SM, Fernando SD,  Rajapakse S
Publication year: 2018

Balaji K, Weeratunga  PN,  Ramchandani KC, Wijerathne PBP, Sam G, Fernando N,
Handunnetti SM, Fernando SD,  Rajapakse S, Microscopic Agglutination Titre (MAT) for leptospirosis and associations in a population cohort in a high endemic region in Sri Lanka, Proceedings of the 10th Annual Scientific Sessions, IBMBB, University of Colombo, 2018, pp

In vitro study on the effect of antimicrobial agents on inflammatory cytokine response in leptospirosis

Oral Presentations
Sam G, Fernando N, Rajapakse S, Handunnetti SM
Publication year: 2018

Sam G, Fernando N, Rajapakse S, Handunnetti SM, In vitro study on the effect of antimicrobial agents on inflammatory cytokine response in leptospirosis, Proceedings of the 10th Annual Scientific Sessions, IBMBB, University of Colombo, 2018, pp 25

Direct degranulation of rat mast cells (RBL-2H3) and increase in generation of superoxide anion (O2-) induced by aqueous extract of Acacia pollen and Apis dorsata venom

Oral Presentations
Ishaka GKD, Gangani PD, Rukshala BAD, Gunasekara DLPE, Fernando N, Handunnetti SM
Publication year: 2018

Ishaka GKD, Gangani PD, Rukshala BAD, Gunasekara DLPE, Fernando N, Handunnetti SM, Direct degranulation of rat mast cells (RBL-2H3) and increase in generation of superoxide anion (O2-) induced by aqueous extract of Acacia pollen and Apis dorsata venom, Proceedings of the 10th Annual Scientific Sessions, IBMBB, University of Colombo, 2018, pp 20

Development of a Colourimetric Reverse Transcription Loop-mediated Isothermal Amplification assay for the rapid detection of different Serotypes of the Dengue virus

Oral Presentations
Ariyaratne MHJD, Nguyen A, De Silva AD, Fernando N, Weerasena OVDSJ, Handunnetti SM
Publication year: 2018

Ariyaratne MHJD, Nguyen A, De Silva AD, Fernando N, Weerasena OVDSJ, Handunnetti SM, Development of a Colourimetric Reverse Transcription Loop-mediated Isothermal Amplification assay for the rapid detection of different Serotypes of the Dengue virus, Proceedings of the 10th Annual Scientific Sessions, IBMBB, University of Colombo, 2018, pp 26

Comparison of a two-step and a novel single step method for neutrophil isolation

Poster Presentation
Lakmali AKD , Fernando N, Handunnetti SM, Premawansa S
Publication year: 2018

Lakmali AKD , Fernando N, Handunnetti SM, Premawansa S, Comparison of a two-step and a novel single step method for neutrophil isolation, Proceedings of the 10th Annual Scientific Sessions, IBMBB, University of Colombo, 2018

A preliminary study on VP1 gene based genotyping of BK virus isolated from kidney transplant patients

Poster Presentation
Ratnayake AKDVY, Jayamaha CJS, Fernando N, Gajanayake T
Publication year: 2018

Ratnayake AKDVY, Jayamaha CJS, Fernando N, Gajanayake T, A preliminary study on VP1 gene based genotyping of BK virus isolated from kidney transplant patients, Proceedings of the 10th Annual Scientific Sessions, IBMBB, University of Colombo, 2018, pp

 

The in vitro effect of pathogenic Leptospiraon FOXP3 expression in lymphocytes

Oral Presentations
Dayarathna HMSP, Fernando N, Handunnetti SM, Weerasena OVDSJ
Publication year: 2017

Dayarathna HMSP, Fernando N, Handunnetti SM, Weerasena OVDSJ. The in vitro effect of pathogenic Leptospiraon FOXP3 expression in lymphocytes. Proceedings of the 9th Annual Scientific Sessions, IBMBB, University of Colombo, 2017, pp 17.

The effect of Munronia pinnata on Natural Killer (NK-92MI) cell

Poster Presentation
Fernando AN, Fernando N, Handunnetti SM, Hapuaarachchi S
Publication year: 2017

Fernando AN, Fernando N, Handunnetti SM, Hapuaarachchi S, The effect of Munronia pinnata on Natural Killer (NK-92MI) cells, Proceedings of the 9th Annual Scientific Sessions, IBMBB, University of Colombo, 2017, pp 33.

 

Multilocus Sequence Typing of Leptospira from clinical isolates in Sri Lanka

Poster Presentation
Karunanayake Lilani, Vimal Raj R, Anwesh M, Muruganandam N, Perera R, Niloofa R, Fernando N, Handunnetti S. Premawansa S, Rajapakse S., Vijayachari P
Publication year: 2017

Karunanayake Lilani, Vimal Raj R, Anwesh M, Muruganandam N, Perera R, Niloofa R, Fernando N, Handunnetti S. Premawansa S, Rajapakse S., Vijayachari P.  Multilocus Sequence Typing of Leptospira from clinical isolates in Sri Lanka, 10th International Leptospirosis Society Scientific Meeting, Palmerstone, New Zealand, 27th Nov-1stDec 2017, pp 251

 

Leptospirosis: challenges in diagnosis, and predictors of severity

Publications in peer reviewed Journals
Senaka Rajapakse, Narmada Fernando, MJR Niloofa, H. Janaka de Silva, Lilani Karunanayake, Sunil Premawansa, Shiroma Handunnetti
Publication year: 2017

Senaka Rajapakse, Narmada Fernando, MJR Niloofa, H. Janaka de Silva, Lilani Karunanayake, Sunil Premawansa, Shiroma Handunnetti (2017) Leptospirosis: challenges in diagnosis, and predictors of severity. Journal of the Ceylon College of Physicians. 47(2), pp.60–69.