Ongoing Projects

Type I Interferons as an Initiating Driver of Fibrosis in Idiopathic Pulmonary Fibrosis (IPF)

Type I interferons (IFN-I) are a family of cytokines mainly consisting of IFN-α and IFN-β, which play important roles in antiviral immunity and regulation of inflammatory responses. Recent research suggests that, in certain contexts, abnormal or persistent activation of Type I interferon pathways may contribute to the initiation and progression of Idiopathic Pulmonary Fibrosis (IPF).

Sarcoidosis is a chronic, multisystem inflammatory disease characterized by the formation of non-caseating granulomas in affected organs, most commonly the lungs and lymph nodes.

Dengue is a mosquito-borne viral disease caused by the Dengue virus (DENV), a member of the Flaviviridae family. Although dengue is primarily considered a systemic viral infection, the liver is one of the major target organs involved in disease progression.

Dengue is one of the most important neglected tropical diseases (NTDs) caused by the Dengue virus (DENV), a mosquito-borne flavivirus transmitted mainly by Aedes aegypti and Aedes albopictus mosquitoes.

Dengue is a major neglected tropical disease (NTD) caused by the Dengue virus (DENV) and transmitted by Aedes mosquitoes.

Neglected Tropical Diseases (NTDs) are a group of infectious diseases that mainly affect populations living in tropical and subtropical regions, particularly in low- and middle-income countries. These diseases are often associated with:

• Poverty
• Limited healthcare access
• Weak disease surveillance systems
• Insufficient investment in drug development

Single-cell immunology is an advanced technology that allows scientists to study the immune system by analysing individual cells rather than large populations of cells.

Traditional immunology methods analyse millions of cells together and provide an average response. However, immune responses are highly complex because different immune cells may behave differently during infection.

Snakebite envenoming is recognized by the World Health Organization (WHO) as a neglected tropical disease (NTD) because it causes significant morbidity and mortality, particularly in tropical and rural communities.