Research & Grants

Research Interests

  • Research interest - 1
  • Research interest - 2

Research Grants

  • Rapid, point-of-care antigen tests for diagnosis of SARS-CoV-2 infection. Cochrane Database Syst Rev 11, Cd013705. (2025)
  • Temporo-spatial cellular atlas of the regenerating alveolar niche in idiopathic pulmonary fibrosis. Nature Communications 16, 7150 (2025).
  • Topology across scales on heterogeneous cell data. PLoS Computational Biology 21, e1013460 (2025).
  • Early circulating biomarker signatures of dengue-associated plasma leakage uncovered by proteomics. medRxiv (2025).
  • Posterior reversible encephalopathy syndrome in severe leptospirosis: a case report. IDCases, e02330 (2025).
  • Between-and within-host mutation of dengue virus. Virology, 110750 (2025).
  • Chikungunya masquerading as dengue infection in Sri Lanka uncovered by metagenomics. PLOS ONE 20, e0326995 (2025).
  • Protocol for the Isolation and Analysis of Extracellular Vesicles From Peripheral Blood: Red Cell, Endothelial, and Platelet-Derived Extracellular Vesicles. Bio Protocol 15 (2025).
  • Early circulating biomarkers to predict plasma leakage in dengue fever. Journal of Infection.
  • Nine fatal cases of dengue: a case series from an intensive care unit in Sri Lanka. Tropical Medicine and Health 2024, 52(1):90.
  • High serum levels of reactive nitrogen species and low total antioxidant capacity in patients with resistant hypertension compared to those in age-gender matched healthy controls, controlled hypertension and follow up with propranolol treatment in the extended APPROPRIATE trial. BMC Research Notes 2024, 17(1):223.
  • Haemotoxicity of snakes: a review of pathogenesis, clinical manifestations, novel diagnostics and challenges in management. Transactions of The Royal Society of Tropical Medicine and Hygiene 2025:trae058.
  • Temporo-spatial cellular atlas of the regenerating alveolar niche in idiopathic pulmonary fibrosis. medRxiv 2024:2024.2004.2010.24305440.
  • Exploring synthesis as a vital cognitive skill in complex clinical diagnosis. Diagnosis. 2024(0).
  • Immune mechanisms of granuloma formation in sarcoidosis and tuberculosis. The Journal of Clinical Investigation. 2024;134(1).
  • Development of a machine learning model for early prediction of plasma leakage in suspected dengue patients. PLOS Neglected Tropical Diseases. 2023;17(3):e0010758.
  • Hirudin versus citrate as an anticoagulant for ROTEM platelet whole blood impedance aggregometry in thrombocytopenic patients. Platelets. 2023;34(1):2229909.
  • Immune mechanisms in fibrotic pulmonary sarcoidosis. European Respiratory Review. 2023;32(169):225178.
  • Single cell spatial analysis reveals inflammatory foci of immature neutrophil and CD8 T cells in COVID-19 lungs. Nature Communications. 2023;14(1):7216.
  • Unilateral Osler nodes, Janeway lesions and splinter haemorrhages associated with surgical arterio-venous fistula infection: a case report. BMC Infectious Diseases. 2023;23(1):451.
  • Genomic Surveillance of Recent Dengue Outbreaks in Colombo, Sri Lanka. Viruses. 2023;15(7):1408.
  • Spatial transcriptomic characterization of COVID-19 pneumonitis identifies immune circuits related to tissue injury. JCI insight. 2023;8(2).
  • Rotational thromboelastometry in critical phase of dengue infection: Association with bleeding. Research and Practice in Thrombosis and Haemostasis. 2022;6(3):e12704.
  • Immune mechanisms in fibrotic pulmonary sarcoidosis. European Respiratory Review. 2022;31(166).
  • Effect of prior Zika and dengue virus exposure on the severity of a subsequent dengue infection in adults. Scientific Reports. 2022;12(1):17225.
  • Unbiased single cell spatial analysis localises inflammatory clusters of immature neutrophils-CD8 T cells to alveolar progenitor cells in fatal COVID-19 lungs. MedRxiv. 2022:2022.12. 21.22283654.
  • Pulmonary involvement in primary systemic vasculitides. Rheumatology. 2022;61(1):319-30.
  • Management of Sarcoidosis: When to Treat, How to Treat and for How Long? Current Pulmonology Reports. 2022;11(4):151-9.
  • Antibody tests for identification of current and past infection with SARS‐CoV‐2. Cochrane database of Systematic reviews. 2022(11).
  • Glucose‐6‐phosphate dehydrogenase deficiency near‐patient tests for tafenoquine or primaquine use with Plasmodium vivax malaria (Protocol). Cochrane Database of Systematic Reviews. 2021;2021(1):CD013861.
  • Rational use of ultrasonography with triaging of patients to detect dengue plasma leakage in resource limited settings: A prospective cohort study. Tropical Medicine & International Health. 2021;26(8):993-1001.
  • Dengue and post-infection fatigue: findings from a prospective cohort—the Colombo Dengue Study. Transactions of the Royal Society of Tropical Medicine and Hygiene. 2021;115(6):669-76.
  • Direct costs of managing in-ward dengue patients in Sri Lanka: A prospective study. Plos one. 2021;16(10):e0258388.
  • Association between age at disease onset of anti-neutrophil cytoplasmic antibody–associated vasculitis and clinical presentation and short-term outcomes. Rheumatology. 2021;60(2):617-28.
  • Effectiveness of native language prescription in improving medication knowledge. 2021.
  • The impact of propranolol on nitric oxide and total antioxidant capacity in patients with resistant hypertension—evidence from the APPROPRIATE trial. BMC Research Notes. 2020;13(1):1-5.
  • Seroprevalence of leptospirosis in an endemic mixed urban and semi-urban setting—A community-based study in the district of Colombo, Sri Lanka. PLoS Neglected Tropical Diseases 14(5), e0008309 (2020).
  • Carica papaya extract in dengue: a systematic review and meta-analysis. 2020.
  • Immunoglobulin replacement and quality of life after CAR T-cell therapy. The Lancet Oncology. 2020;21(1):e6.
  • Successful medical management of a retroperitoneal abscess: a difficult diagnosis in pyrexia of unknown origin. Case Reports in Infectious Diseases. 2020;2020:1-5.
  • Anemia as a predictor of functional disability in the early stage of ischemic stroke in a South Asian Population. Annals of Indian Academy of Neurology. 2020;23(4):515.
  • Single molecule, near full-length genome sequencing of dengue virus. Scientific reports. 2020;10(1):18196.
  • Risk prediction for severe disease and better diagnostic accuracy in early dengue infection; the Colombo dengue study. BMC Infectious Disease. 2019;1(19(1)):680.
  • Carica papaya extract in dengue: a systematic review and meta-analysis. BMC complementary and alternative medicine. 2019;19:1-8.
  • Reversible splenial lesion syndrome associated with dengue fever: a case report. 2019.
  • Evaluation of the accuracy and precision of glucometers currently used in Sri Lanka. Diabetes & Metabolic Syndrome: Clinical Research & Reviews. 2019;13(3):2184-8.
  • Miller Fisher syndrome developing as a parainfectious manifestation of dengue fever: a case report and review of the literature. Journal of Medical Case Reports. 2019;13:1-4.
  • Cytomegalovirus induced refractory TTP in an immunocompetent individual: a case report. BMC Infectious Diseases. 2019;19(1):1-4.
  • Reversible splenial lesion syndrome associated with dengue fever: a case report. BMC Research Notes. 2018;11(1):1-4.
  • Beyond thrombocytopaenia, haemorrhage and shock: the expanded dengue syndrome. Pathogens and global health. 2018;112(8):404-14.
  • MRI findings in a patient with upper motor neuron dominant amyotrophic lateral sclerosis. Sri Lanka Journal of Neurology. 2018;5(1).
  • Embolizing pulmonary aspergillosis, mycobacterial & aspergillous splenic abscess and cytomegalovirus co-infection following steroid induced immunosuppression: a case report. BMC Infectious Diseases. 2018;18:1-5.
  • Evolution into Takayasu arteritis in a patient presenting with acute pulmonary oedema due to severe aortic regurgitation. 2018.
  • Evolution into Takayasu arteritis in a patient presenting with acute pulmonary oedema due to severe aortic regurgitation; a case report. BMC rheumatology. 2018;2(1):1-6.
  • Control methods for Aedes albopictus and Aedes aegypti. The Cochrane Database of Systematic Reviews. 2017;2017(8).
  • Clinical manifestations of scrub typhus. Transactions of the Royal Society of Tropical Medicine and Hygiene. 2017;111(2):43-54.
  • Prophylaxis of human toxoplasmosis: a systematic review. Pathogens and global health. 2017;111(7):333-42.
  • Transactions of the Royal Society of Tropical Medicine and Hygiene. 2017;111(10):433-9.
  • Addition of Propranolol in Resistant Arterial hypertension Treatment (APROPRIATE study): study protocol for a randomized double-blind placebo-controlled trial. Trials. 2017;18:1-7.
  • Amphotericin B for treatment of visceral leishmaniasis; a systematic review and meta-analysis of prospective, comparative clinical studies including dose ranging studies. Clinical Microbiology and Infection. 2017.
  • Closing the theory to practice gap for newly qualified doctors: evaluation of a peer-delivered practical skills training course for newly qualified doctors in preparation for clinical practice. Postgraduate medical journal. 2017;93(1104):592-6.
  • Plasmodium falciparum and Mycoplasma pneumoniae co-infection presenting with cerebral malaria manifesting orofacial dyskinesia and haemophagocytic lymphohistiocytosis. Malaria Journal. 2016;15:1-3.
  • Clinicopathological correlates of chronic kidney disease of unknown etiology in Sri Lanka. Indian journal of nephrology. 2016;26(5):357.
  • Clinical and laboratory associations of severity in a Sri Lankan cohort of patients with serologically confirmed leptospirosis: a prospective study. Trans R Soc Trop Med Hyg. 2016;110:261.
  • A diagnostic scoring model for leptospirosis in resource limited settings. PLoS Neglected Tropical Diseases. 2016;10(6):e0004513.
  • Mucormycosis–deadly disease and deadly treatment. Sri Lanka Journal of Neurology. 2015;4(1).
  • Determinants of mortality and impact of therapy in patients with leptospirosis admitted for intensive care in a Sri Lankan hospital–a three year retrospective study. Pathogens and global health. 2015;109(8):387-94.
  • Clinico epidemiological characteristics, treatment and outcomes of patients with confirmed Leptospirosis in a Sri Lankan healthcare setting. 2015.
  • Clinical and laboratory associations of severity in a Sri Lankan cohort of patients with serologically confirmed leptospirosis: a prospective study. Transactions of the Royal Society of Tropical Medicine and Hygiene. 2015;109(11):710-6.
  • Endocarditis of a Native Cardiac Valve due to Salmonella typhi-A Case Report. Prensa Med Argent. 2015;101(6):2.
  • Cardiovascular risk in lupus nephritis: Do renal disease-related and other traditional risk factors play a role? Saudi Journal of Kidney Diseases and Transplantation. 2015;26(3):526-35.
  • Neurological manifestations of dengue: a cross sectional study. Travel Medicine and Infectious Disease. 2014;12(2):189-93.
  • Per capita sugar consumption and prevalence of diabetes mellitus–global and regional associations. BMC public health. 2014;14(1):1-6.
  • Teaching video neuroimages: orofacial dyskinesia and oral ulceration due to involuntary biting in neuroacanthocytosis. Neurology. 2014;82(8):e70-e.
  • Toxic encephalopathy due to colchicine— Gloriosa superba poisoning. Practical neurology. 2014.
  • Spontaneously resolving cerebellar syndrome as a sequelae of dengue viral infection: a case series from Sri Lanka. Practical neurology. 2013.
  • Multiple sclerosis in a series of Sri Lankan patients--Clinical and radiological characteristics. Neurology Asia. 2013;18(2).
  • Medical student research output in a developing country: Where has all the research gone? Medical teacher. 2012;34(11):998-.