Professor Chamari M. Hettiarachchi

Professor in Molecular Biology & Biochemistry

Department of Chemistry
University of Colombo
Colombo 00300
Sri Lanka

Office: Department of Chemistry, Room: 129
Work Phone: +94 11-250 3367
Work Fax: +94 11-250 3367
Email: chamarih@chem.cmb.ac.lk

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Academic & Professional Qualifications

  • PhD 2003

    PhD - Plant Molecular Biology & Biochemistry

    Jawaharlal Nehru University, New Delhi

  • BSc 1996

    BSc - Special Degree in Botany (Second Class Upper Division)

    University of Colombo

      Teaching

      • Molecular Biology, Biochemistry & Microbiology

      Research Interests

      • My main research interest is on light and abiotic stress signaling pathway and developemnt of transgenic plants.   During my postdoc, I studied a group of Arabidopsis proteins (STO, STH, STH2 & STH3) that were identified through their interactions with two key regulators of light signaling, COP1 and HY5. Also The Arabidopsis plants with mutations in the STH2 gene showed hypersensitivity to Abscisic acid (ABA), a drought and salt stress regulating hormone, and to NaCl in germination and root growth assay. Furthermore, the expression of several key regulators of ABA signaling was altered in the sth2 mutant indicating that the STH2 gene plays an important role in response to drought and salinity. Hence, applying this knowledge gained from  Arabidospsis on rice could be  a worth effort to obtain drought and salinity  tolerance Sri Lankan rice varieties.
      • Production of recombinant industrial enzymes
      • Natural Product Chemistry – screening of medicinal plants and marine sponges to check their potential to develop antimicrobial, anticancer and anti-inflammatory drugs
      • Investigation of the possibility of using FITC-doped silica nanoparticles as a biosensor for bacterial detection