Postgraduate –
MSc Molecular Life Sciences – Cell Biology, Cellular communications, Cells in Social Context, Biological Membranes, Membrane Transport, Signal transduction, DNA replication, DNA repair, Cell Cycle, Cancer Biology and Cancer Genetics, Molecular Medicine
MSc Cellular and Molecular Immunology – Cell Biology, Cancer Biology and Cancer Genetics
MSc Bioinformatics – Genetics, Genomics, Biochemistry and Cell Biology
MD Clinical Oncology – Cancer Biology / Cancer Genetics
Undergraduate medical students, BSc Pharmacy students, paramedical students (AMP, Physiotherapy, Radiology, Ophthalmic technicians, postbasic nurses)
MSc Biochemistry, Molecular Biology and Botechnology – Faculty of Medicine
Undergraduate
Physiology curriculum for Medical students
Postgraduate
MSc Molecular Life Sciences – Cell Biology, Cellular communications, Cells in Social Context, Biological Membranes, Membrane Transport, Signal transduction, DNA replication, DNA repair, Cell Cycle, Cancer Biology and Cancer Genetics, Molecular Medicine
MSc Cellular and Molecular Immunology – Cell Biology, Cancer Biology and Cancer Genetics
MSc Bioinformatics – Genetics, Genomics, Biochemistry and Cell Biology
MD Clinical Oncology – Cancer Biology / Cancer Genetics
| Name of the Student | PhD/MPhil year of completion | Title of the Thesis | Principal / co-supervisor |
|---|---|---|---|
| S Jeevathayaparan | PhD
1999
|
Oral hypoglycaemic activity of Momordica charantia: Possible mechanismssms of action and activity related fractionation | Co-supervisor |
| S Wasalathanthri | PhD
2001
|
Lactational amenorrhoea and some of its determinants in well-
nourished and undernourished women |
Principal and sole supervisor |
| A N Pathmaperuma
|
MPhil
2006
|
A study on insulin-like growth factor –I, insulin-like growth factor binding protein-1 and major placental hormones during normal pregnancy | Principal supervisor |
| T Eswaramohan | PhD
2008
|
Expression of leptin and leptin receptors in the female reproductive tract and effect of leptin on endometrial cell function in the rat | Principal supervisor |
| J W N De Silva
|
PhD
2009 |
Characterisation of sequence variants in the breast cancer susceptibility gene 1 (BRCA1) in selected Sri Lankan breast cancer patients and at risk individuals | Co-supervisor |
| A Murugananthan | MPhil
2010 |
Cloning and characterisation of Ackali myosin light chain gene (Mlc-3) of cattle filarial parasite Setaria digitata | Co-supervisor
|
| P Jayanthiny
|
PhD
2012
|
Insulin-like growth factor (IGF)-I, IGF-II and H 19 genotypes in a Sri Lankan birth cohort: Effect on maternal and cord blood levels of IGF-I and IGF binding protein-1, cord blood IGF-II and birth size | Principal supervisor |
| Sumadee De Silva
|
PhD
2013 |
Characterisation of mutations and sequence variants in breast cancer susceptibility (BRCA) 2 gene in a selected group of breast cancer patients in Sri Lanka | Principal supervisor |
| Y N Silva | PhD
2012
|
Association between endometriosis and heavy metals in a group of Sri Lankan women of reproductive age | Co-supervisor
|
| SSR Samarakoon | PhD
2014 |
Anti-hepatocarcinogenic effect of a traditional Sri Lankan herbal remedy: Modulation of expression of selected genes associated with carcinogenesis and identification of active compounds | Co-supervisor |
| RACR Ranasinghe | PhD
2016 |
Mitochondrial DNA analysis, haplotype and haplogroup determination and inference of maternal lineage in five major ethnic groups and Vedda population in Sri Lanka | Principal supervisor |
| MACP Piyathilake | PhD
2015
|
Molecular Identification of Toxigenic Cyanobacteria and Effects of Cyanotoxins on Human Renal Cell Lines | Co-supervisor |
| AS Hewage | PhD
2017 |
Selected polymorphisms of the H19 and IGF-II genes in a Sri Lankan birth cohort: Effect of maternal and newborn genotype on birth size | Principal supervisor |
| EPM Keshawa | PhD
2017 |
Possible anti-carcinogenic effects of Mangifera zeylanica: Identification of active compounds and evaluation of molecular mechanism | Principal supervisor |
| HACIK Rodrigo | PhD 2018 | Predictive biomarkers for sporadic breast cancer: Evaluation of circulating levels of leptin, soluble leptin receptor, insulin-like growth factor I, insulin-like growth factor binding protein-3 and visfatin and selected leptin and leptin receptor genotypes | Principal supervisor |
| AS Mendis | PhD 2019 | To evaluate potential use of flueggea leucopyrus & vernonia zeylanica in the treatment of breast cancer | Co-supervisor |
| K Senathilake | PhD 2019 | Search for antifilarial drugs from Sri Lankan medicinal plants | Co-supervisor |
| T Sundralingam | PhD 2019 | Characterization of mutations and sequence variants of growth hormone (GH) and growth hormone releasing hormone receptor (GHRH-R) in a cohort of Sri Lankan children with GH deficiency | Principal supervisor |
| K Senanayake | MPhil in progress* | Analysis of Setaria digitata Genome using NGS Technologies: Identification of potential drug targets in Setaria digitata | Co-supervisor |
| V Manoharan | PhD in progress | Analysis of somatic mutation of TP53 in selected cancers among Sri Lankan patients | Co-supervisor |
| U Rajagopalan | PhD in progress | Screening of Sri Lankan endemic plants for anti-cancer stem cell activity and evaluation of anti-cancer stem cell properties of isolated compounds from active plants for breast cancer | Co-supervisor |
| MNS Wickramaratne | MPhil in progress* | Isolation structural and functional characterization of active antibreast cancer metabolites from endophytic fungi of plants and selected endemic / medicinal plants of Sri Lanka | Co-supervisor |
| J Thushyanthan | MPhil in progress* | Screening of selected endophytic fungi and endemic plants for anticancer activity using hepatocellular carcinoma (HepG2) cell line and isolation of active compounds | Co-supervisor |
| BMLP Jayasekera | MPhil in progress* | Mutations and polymorphisms of mitochondrial genes as risk factors for sporadic breast cancer in Sri Lankan patients of Sinhalese ethnicity | Principal supervisor |
| JT Kotelawala | MPhil in progress* | Characterisation of Mitochondrial DNA mutations in the D-loop and mtDNA haplogroups in Sporadic Breast Cancer.
|
Principal supervisor |
| RMRK Rathnayake
|
MPhil in progress* | Screening of compound libraries on a cancer cell panel and development of a synthetic anti-cancer compound libraryll line and isolation of active compounds | Co-supervisor |
| A S Fernando | MPhil in progress* | Insight for molecular anthropology of peopling in Sri Lanka: Ancient human mtDNA and molecular sex analysis of archaeological skeletal remains at Udupiyangalge and Alugalge caves | Co-supervisor |
| AADN Perera | MPhil in progress* | Evaluation of anti-cancer effects of Mangifera zeylanica plant extracts on non small lung cancer cell lines | Principal supervisor |
| Nethu Wickramasinghe | MPhil in progress* | Molecular systematics of the blindsnakes (Serpentes: Scolecophidia) of Sri Lanka
|
Co-supervisor |
| Name of the Student | MSc / year of
completion |
Title of the Thesis | Principal / co-supervisor | |
| P Jayanthiny
|
Biochemistry, Molecular Biology and Gene Technology
2006 |
Study of maternal and cord blood insulin-like growth factor (IGF) – I, -II and IGF binding protein–1 levels in normal pregnancies and in pregnancy induced hypertension / pre-eclampsia and gestational diabetes mellitus | Principal supervisor
|
|
| A D Gunaratne
|
Molecular Life Sciences – 2006 | Screening of Sri Lankan breast cancer patients for germ line mutations in exon 8 of TP53 gene | Principal supervisor
|
|
| HVGS Wickramaratne
|
Molecular Life Sciences – 2007 | Screening for germ-line mutations in exon 12 of BRCA 2 gene in as selected group of patients with family history of breast cancer and ovarian cancer | Principal supervisor
|
|
| H A C I K Rodrigo | Molecular Life Sciences – 2007 | Screening of a selected group of Sri Lankan breast cancer patients for germ line mutations in exon 7 of BRCA 2 gene | Principal supervisor
|
|
| RACR Ranasinghe | Molecular Life Sciences -2007 | Optimization of PCR conditions for the amplification of hypervariable region I and hypervariable region II in the human mitochondrial D- loop. | Principal supervisor
|
|
| J.G. Rozani | Molecular Life Sciences -2007 | Screening for germ – line mutations of exon – 8 in the P53 gene in a family with a BRCA – 1 mutation | Principal supervisor | |
| WI Indika | Molecular Life Sciences -2008 | Gin 223Arg polymorphism in the leptin receptor: prevalence among Sri Lankan women with pre-eclampsia / pregnancy induced hypertension | Principal supervisor | |
| K. Vythilingam
|
Molecular Life Sciences -2008 | Characterization of mutations and sequence variants in exon 11 of BRCA1 gene of sporadic breast cancer: A preliminary study on Sri Lankan patients | Principal supervisor | |
| Y.S. Wijayasinghe | Applied Organic Chemistry-2008 | Maternal plasma levels of placental growth factor in pregnancy induced hypertension/pre-eclampsia | Principal supervisor | |
| S D Gnanaratnam | Cellular and Molecular Immunology-2008 | Study of maternal insulin-like growth factor-I levels in normal pregnancies and in pregnancies complicated by pregnancy induced hypertension / pre-eclampsia | Principal supervisor | |
| S Sinnathamby
|
Molecular Life Sciences
2009 |
H19 polymorphism in newborns born to mothers with pregnancy induced hypertension/ preeclampsia | Principal supervisor | |
| T Siriwardena | Molecular Life Sciences -2009 | IGF-II APa-1 polymorphism in newborns, born to mothers with pregnancy induced hypertension / pre-eclampsia | Principal supervisor | |
| P Yasasni
|
Molecular Life Sciences -2010 | The CA promoter polymorphism of IGF-I gene in pre-eclampsia / pregnancy induced hypertension | Principal supervisor
|
|
| SB Kotigala | Molecular Life Sciences -2010 | Effect of an herbal extract on the Caspase-3 and Caspase-9 expression in endometrial carcinoma cells | Principal supervisor
|
|
| B Sinthanaichselvan | Molecular Life Sciences -2012 | A preliminary analysis of mitochondrial haplogroups | Principal supervisor
|
|
| T Sundralingam | Molecular Life Sciences -2014 | Development of a multiplex SNP assay for selected CYP2D6 genotypes | Principal supervisor
|
|
| V Manoharan | Molecular Life Sciences -2014 | Optimization of DNA extraction from paraffin embedded tissues and preliminary analysis of somatic mutation of TP53 in breast cancer | Principal supervisor
|
|
| A Herath | Molecular Life Sciences -2015 | Y chromosome haplolyp analysis of Sri Lankans: A Preliminary study | Principal supervisor
|
|
| OKC De SIlva | Molecular Life Sciences -2015 | Possible potentiation of antiproliferative effect of tamoxifen in MCF-7 breast cancer cells by a bioactive extract of mangrove plant Scyphiphora hydrophyllacea: A pilot study | Co-supervisor | |
| S R Samarasinghe | MSc Bioinformatics
2015 |
In silico analysis of missense mutations in human growth hormone: The impact on protein structure, dynamics and stability | Principal supervisor
|
|
| Karthika M | MSc Bioinformatics
2015 |
Molecular docking study of selected natural compounds for cancer stem cells targeted anti-cancer activity | Co- supervisor | |
| SHDK Jayathilaka | Molecular Life Sciences -2016 | A pilot study on CYP21A2 gene deletion among Sri Lankan children with congenital adrenal hyperplasia
|
Principal supervisor
|
|
| M VML Jayasundara | Molecular Life Sciences -2016 | A pilot study on selected point mutations of CYP21A2 gene among a cohort of Sri Lankan children with Congenital Adrenal Hyperplasia
|
Principal supervisor
|
|
| I Wickramage | Molecular Life Sciences -2016 | Prevalence of selected polymorphisms of CYP2D6 gene in a cohort of breast cancer patients: Association with poor response to Tamoxifen | Principal supervisor | |
| AS Fernando | Molecular Life Sciences -2018 | Extensive analysis of human mitochondrial and Y-chromosome haplogroups among Sinhalese individuals with different Alu polymorphisms | Co- supervisor | |
| S Praveenan | Molecular Life Sciences -2018 | Analysis of common genetic mutations in a cohort of salt wasting form of congenital adrenal hyperplasia | Co- supervisor | |
| AADN Perera | Molecular Life Sciences -2018 | Development of in vitro transgenic model for anti-cancer drug discovery | Co- supervisor | |