Subtypedependent regulation of Gβγ signalling

Peer-reviewed publications
Tennakoon M, Senarath K, Kankanamge D, Ratnayake K, Wijayaratna D, Olupothage K, Ubeysinghe S, Martins-Cannavino K, Hébert TE, Karunarathne A
Publication year: 2021

Tennakoon M, Senarath K, Kankanamge D, Ratnayake K, Wijayaratna D, Olupothage K,
Ubeysinghe S, Martins-Cannavino K, Hébert TE, Karunarathne A (2021) Subtypedependent regulation of Gβγ signalling. Cellular Signaling 82:109947.

A short C-terminal peptide in Gγ regulates Gβγ signaling efficacy

Peer-reviewed publications
Tennakoon M, Senarath K, Kankanamge D, Chadee DN, & Karunarathne A
Publication year: 2021

Tennakoon M, Senarath K, Kankanamge D, Chadee DN, & Karunarathne A (2021) A short C-terminal peptide in Gγ regulates Gβγ signaling efficacy. Molecular Biology of the Cell:mbcE20110750. PMID: 34106735

Microcystins: biogenesis, toxicity, analysis and control

Peer-reviewed publications
Schreidah C.M, Ratnayake K, Senarath K, and Karunarathne A
Publication year: 2020

Schreidah C.M, Ratnayake K, Senarath K, and Karunarathne A (2020), Microcystins:
biogenesis, toxicity, analysis and control. Chemical Research in Toxicology 33(9):2225-
2246.

Statins perturb Gβγ signaling and cell behaviors in a Gγ subtype dependent manner

Peer-reviewed publications
Tennakoon M, Kankanamge D, Senarath K, Fasih Z, & Karunarathne A
Publication year: 2019

Tennakoon M, Kankanamge D, Senarath K, Fasih Z, & Karunarathne A (2019) Statins
perturb Gβγ signaling and cell behaviors in a Gγ subtype dependent manner. Molecular
Pharmacology 95(4):361-375.

Optical approaches for single-cell and subcellular analysis of GPCR–G protein signaling

Peer-reviewed publications
Kankanamge D, Ratnayake K, Senarath K, Tennakoon M, Harmon E, & Karunarathne A
Publication year: 2019

Kankanamge D, Ratnayake K, Senarath K, Tennakoon M, Harmon E, & Karunarathne A
(2019) Optical approaches for single-cell and subcellular analysis of GPCR–G protein
signaling. Analytical and Bioanalytical Chemistry 411(19):4481-4508.

Gγ identity dictates efficacy of Gβγ signaling and macrophage migration

Peer-reviewed publications
Senarath K, Payton JL, Kankanamge D, Siripurapu P, Tennakoon M, & Karunarathne A
Publication year: 2018

Senarath K, Payton JL, Kankanamge D, Siripurapu P, Tennakoon M, & Karunarathne A
(2018) Gγ identity dictates efficacy of Gβγ signaling and macrophage migration. Journal
of Biological Chemistry 293(8):2974-2989.

G protein γ (Gγ) subtype dependent targeting of GRK2 to M3 receptor by Gβγ

Peer-reviewed publications
Samaradivakara S, Kankanamge D, Senarath K, Ratnayake K, & Karunarathne A
Publication year: 2018

Samaradivakara S, Kankanamge D, Senarath K, Ratnayake K, & Karunarathne A (2018)
G protein γ (Gγ) subtype dependent targeting of GRK2 to M3 receptor by Gβγ.
Biochemical and biophysical research communications 503(1):165-170

Chapter Five - Regulation of G Protein βγ Signaling

Peer-reviewed publications
Senarath K, Kankanamge D, Samaradivakara S, Ratnayake K, Tennakoon M, & Karunarathne A
Publication year: 2018

Senarath K, Kankanamge D, Samaradivakara S, Ratnayake K, Tennakoon M, &
Karunarathne A (2018) Chapter Five – Regulation of G Protein βγ Signaling. International
Review of Cell and Molecular Biology, ed Shukla AK (Academic Press), Vol 339, pp 133-
191.

Two independent but synchronized Gβγ subunit−controlled pathways are essential for trailingedge retraction during macrophage migration

Peer-reviewed publications
Siripurapu P, Kankanamge D, Ratnayake K, Senarath K, & Karunarathne A
Publication year: 2017

Siripurapu P, Kankanamge D, Ratnayake K, Senarath K, & Karunarathne A (2017) Two
independent but synchronized Gβγ subunit−controlled pathways are essential for trailingedge retraction during macrophage migration. Journal of Biological Chemistry
292(42):17482-17495.

Chapter 1 - Measurement of GPCR-G protein activity in living cells

Peer-reviewed publications
Ratnayake K, Kankanamge D, Senarath K, Siripurapu P, Weis N, Tennakoon M, Payton JL, & Karunarathne A
Publication year: 2017

Ratnayake K, Kankanamge D, Senarath K, Siripurapu P, Weis N, Tennakoon M, Payton
JL, & Karunarathne A (2017) Chapter 1 – Measurement of GPCR-G protein activity in
living cells. Methods in Cell Biology, ed Shukla AK (Academic Press), Vol 142, pp 1-25.

Reversible G Protein βγ9 Distribution-Based Assay Reveals Molecular Underpinnings in Subcellular, Single-Cell, and Multicellular GPCR and G Protein Activity

Peer-reviewed publications
Senarath K, Ratnayake K, Siripurapu P, Payton JL, & Karunarathne A
Publication year: 2016

Senarath K, Ratnayake K, Siripurapu P, Payton JL, & Karunarathne A (2016) Reversible
G Protein βγ9 Distribution-Based Assay Reveals Molecular Underpinnings in Subcellular,
Single-Cell, and Multicellular GPCR and G Protein Activity. Analytical Chemistry
88(23):11450-11459.

Non Specific Amplification with the LAMP Technique in the Diagnosis of Tuberculosis in Sri Lankan Settings

Peer-reviewed publications
Senarath KD, Usgodaarachchi, R., Navaratne, V., Nagahawatte, A., Wijayarathna, C., Alvitigala, J. and Goonasekara, C.
Publication year: 2014

Senarath KD, Usgodaarachchi, R., Navaratne, V., Nagahawatte, A., Wijayarathna, C.,
Alvitigala, J. and Goonasekara, C. (2014) Non Specific Amplification with the LAMP
Technique in the Diagnosis of Tuberculosis in Sri Lankan Settings. Journal of Tuberculosis
Research 2(4):168-172.