Manoharan, V., Karunanayake, E.H., Tennekoon, K.H., De Silva, S., Imthikab A.I.A, Kanishka
De Silva, Angunawela, P., Vishwakula, S & Lunec, J. Pattern of nucleotide variants of TP53 and
their correlation with the expression of p53 and its downstream proteins in a Sri Lankan cohort
of breast and colorectal cancer patients. BMC Cancer 20, 72 (2020). Doi:
https://doi.org/10.1186/s12885-020-6573-5
De Silva S, Tennekoon KH , Karunanayake EH. Overview of the genetic basis towards early detection of breast cancer. Breast Cancer: Targets and Therapy, 2019
Manoharan V, Karunanayake EH, Tennekoon KH, De Silva S, De Silva K, Angunawela P, Lunec J. Nucleotide variants and protein expression of TP53 in a Sri Lankan cohort of head and neck cancer patients. Molecular Medicine Reports, 2019
Imthikab AIA, De Silva S, De Silva K. Detection of somatic mutations of KRAS, BRAF and PIK3CA in a cohort of patients with colorectal carcinoma in Sri Lanka. Proceedings of the 11th Annual Scientific Sessions, Institute of Biochemistry, Molecular Biology and Biotechnology: 2019. Pp 17 (OP03)
Sundralingam T, Tennekoon KH, de Silva KSH, De Silva S, Hewage AS, Ranasinghe R. Detection of a heterozygous deletion in the LHX4 gene locus in a child with growth hormone deficiency and its impact on the child. Sri Lanka Journal of Diabetes Endocrinology and 2019;9(2Suppl1):23.
Manoharan V, Karunanayake EH, Tennekoon KH, De Silva S, Angunawela P, De Silva K, Lunec J. Comparison between cDNA and DNA sequencing in detection of TP53 variants in head and neck, breast and colorectal cancers. Proceedings of the 11th Annual Scientific Sessions, Institute of Biochemistry, Molecular Biology and Biotechnology: 2019. pp 18 (OP04)
Manoharan V, Karunanayake EH, Tennekoon KH, De Silva S, De Silva K, Angunawela P, Lunec J. Association of TP53 codon 72 polymorphism with selected human cancer types in Sri Lanka. Proceeding of the 8th Young Scientist Forum Research Symposium, National Science and Technology Commission, 2019
Sundralingam T, Tennekoon KH, de Silva S, De Silva S, Hewage AS, Ranasinghe R. Novel gross deletion at the GHRHR gene locus possibly mediated by Alu specific microhomology identified in a Sri Lankan patient with isolated growth hormone deficiency. Growth Hormone & IGF Research, 2018; 42–43:94-101. Doi: https://doi.org/10.1016/j.ghir.2018.10.005
Sundralingam T, Tennekoon KH, de Silva KSH, De Silva S, Hewage AS. Novel gross deletion at the GHRHR gene locus discerned in a Sri Lankan patient with isolated growth hormone deficiency. Ceylon Med J. 2018;63(Suppl1):81
Sundralingam T, Tennekoon KH, de Silva KSH, De Silva S, Hewage AS, Ranasinghe R. Charaterization and identification of the mechanism behind formation of a novel gross deletion at GHRHR gene locus leading to isolated growth hormone deficiency. Proceedings of the 10th Annual Scientific Sessions, Institute of Biochemistry, Molecular Biology and Biotechnology: 2018. pp 17 (OP05)
Manoharan V, Karunanayake EH, Tennekoon KH, De Silva S, Angunawela P,De Silva K, Lunec J. Association of TP53 mutations and p53 protein expression in a cohort of Sri Lankan head and neck cancer patients. Proceedings of the 10th Annual Scientific Sessions, Institute of Biochemistry, Molecular Biology and Biotechnology: 2018. pp 17 (OP03)
Vahinipriya M, Karunanayake E, Tennekoon K, De Silva S, De Silva K, Angunawela P, Lunec J. Somatic mutations in the TP53 tumor suppressor gene in Sri Lankan patients with Head and Neck cancer. Proceedings of the 3rd European Association for Cancer Research Conference on Cancer Genomics 2017. Cambridge, UK
Vahinipriya M, Karunanayake EH, Tennekoon KH, De Silva S, Angunawela P, De Silva K, Mahdi A, Zanjirband M, Lunec J. Relationship between p53 immunohistochemistry staining pattern and TP53 gene mutation type in Sri Lankan patients with head and neck cancer. North East Postgraduate Conference 2017, Newcastle, UK.
Sundralingam T, Tennekoon KH, De Silva KSH, De Silva S, Hewage AS. Pathogenic and possibly pathogenic genetic alterations of the GH1 and GHRHR genes detected in a cohort of IGHD children in Sri Lanka. Proceedings of the European Human Genetics Conference 2017;Copenhagen, Denmark European Journal of Human Genetics. 2019; 26, 861-861
Sundralingam T, Tennekoon KH, De Silva KSH, De Silva S, Hewage AS. Pathogenic and likely pathogenic genetic alterations and polymorphisms in growth hormone gene (GH1) and growth hormone releasing hormone receptor gene (GHRHR) in a cohort of isolated growth hormone deficient (IGHD) children in Sri Lanka. Growth Hormone & IGF Research, 2017; 36: 22–29. Doi: http://dx.doi.org/10.1016/j.ghir.2017.08.006
Sundralingam T, Tennekoon KH, de Silva KSH, De Silva S, Hewage AS. Novel variants of GHRHR gene observed in a cohort of isolated growth hormone deficient children in Sri Lanka. Proceedings of the 130th Anniversary International Medical Congress of the Sri Lanka Medical Association; 2017. pp 163 (PP063)
De Silva, S, Tennekoon, KH, Dissanayake, A, De Silva K, Jayasekera L. Novel and reported pathogenic variants in exon 11 of BRCA2 gene in a cohort of Sri Lankan young breast cancer patients. Familial Cancer. 2017; 16(3): 329–338. Doi: 10.1007/s10689-016-9962-9
Sundralingam T, Tennekoon KH, de Silva KSH, De Silva S, Hewage AS. GHRHR gene variants observed in combination of IGHD children in Sri Lanka. Proceedings of the 9th Annual Scientific Sessions, Institute of Biochemistry, Molecular Biology and Biotechnology: 2017. pp 13 (OP 02)
Jayasundara GP, De Silva S, De Silva, K. Detection of pathogenic mutations in hotspot regions in exon 11 of BRCA1 gene in a cohort of Sri Lankan young familial breast cancer patients. Proceedings of the 9th Annual Scientific Sessions, Institute of Biochemistry, Molecular Biology and Biotechnology: 2017. pp 29 (PP 01)
Silva N, de Silva S, Jayawardene G, Senanayake H. Detection of IGF-II 820G>A polymorphism in a group of Sri Lankan women in endometriosis. Proceedings of the Scientific Sessions, Faculty of Sciences, university of Sri Jayawardenapura: 2017. pp 71 (PP 30)
Manoharan V, Lunec J, Esfandiari A, Mahdi A, Wu C-E, Zanjirband M, Karunanayake EH, Tennekoon KH, De Silva S. Cytotoxic potential of the RG7388 MDM2-p53 binding antagonist and the GSK2830371 WIP1 inhibitor on MX- 1 and MCF-7 human breast cancer cells [abstract]. In: Proceedings of the 2016 San Antonio Breast Cancer Symposium; 2016 Dec 6-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2017;77(4 Suppl). Doi: 10.1158/1538-7445
Jayathilaka D K, Tennekoon K H, de Silva KSH, De Silva S. A pilot study on CYP21 gene deletions among a cohort of Sri Lankan children with congenital adrenal hyperplasia, Ceylon Medical Journal, 2017; 62(2); 112–113. Doi: http://doi.org/10.4038/cmj.v62i2.8479
Sundralingam T, Tennekoon KH, de Silva KSH, De Silva S, Hewage AS. Sequence variants in the promoter region of GH1 gene in a cohort of growth hormone deficient (GHD) children in Sri Lanka. Proceedings of the 8th Annual Scientific Sessions, Institute of Biochemistry, Molecular Biology and Biotechnology: 2016. pp 27 (0P 16)
Vahinipriya M , De Silva S, Karunanayake EH, Tennekoon KH, De Silva K. Screening of selected Sri Lankan cancer patients for somatic mutation of TP53 gene. Proceedings of the 8th Annual Scientific Sessions, Institute of Biochemistry, Molecular Biology and Biotechnology: 2016. pp 23 (0P 12)
de Silva K S H, Tennekoon K H, Sundralingam T, Navarathne B, Hewage A S, de Silva WS, Ganihigama D, Jayasinghe H D, Muhandiram M E C. Growth hormone releasing hormone receptor codon 72 mutation in a cohort of Sri Lankan patients with growth hormone deficiency. Ceylon Medical Journal. 2016; 61(1): 18–21.
Sundralingam T, Tennekoon KH, de Silva KSH, Hewage AS, De Silva S. Gross growth hormone deletions in a cohort of isolated growth hormone deficient children in Sri Lanka. Proceedings of the 129th Anniversary International Medical Congress of the Sri Lanka Medical Association; 2016. pp 142 (OP067)
Gamage R, De Silva S, De Silva K, Dissanayake A, Jayasekara L. Association of BRCA2 N372H polymorphism with the risk of early onset of breast cancer in a cohort of Sri Lankan breast cancer patients. Proceedings of the 17th World Congress of Gynecological Endocrinology; 2016; Florence, Italy.
Jayathilaka DK, Tennekoon KH, de Silva KSH, De Silva S. A pilot study on CYP21 gene deletion among a cohort of Sri Lankan children with congenital adrenal hyperplasia. Proceedings of the 129th Anniversary International Medical Congress of the Sri Lanka Medical Association; 2016. pp 142 (OP065)
Jayasekera BMLP, De Silva WS, Tennekoon KH, De Silva K, Dissanayake A. Screening of a cohort of young onset Breast cancer patients for c.2175_2176insA mutation in the BRCA2 gene. Proceedings of the 7th Annual Scientific Sessions, Institute of Biochemistry, Molecular Biology and Biotechnology: 2015. pp 32 (PP 05)
Sundralingam T, Tennekoon KH, De Silva KSH, De Silva S, Hewage AS. GH1 gene sequence variants in a cohort of growth hormone deficient children in Sri Lanka. Proceedings of the Regional Conference of Young Scientists on Nanoscience & Nanomaterial; 2015; Bengaluru, India.