Publication

Pattern of nucleotide variants of TP53 and their correlation with the expression of p53 and its downstream proteins in a Sri Lankan cohort of breast and colorectal cancer patients

Publication
Manoharan, V., Karunanayake, E.H., Tennekoon, K.H., De Silva, S., Imthikab A.I.A, Kanishka De Silva, Angunawela, P., Vishwakula, S & Lunec, J
Publication year: 2020

Manoharan, V., Karunanayake, E.H., Tennekoon, K.H., De Silva, S., Imthikab A.I.A, Kanishka
De Silva, Angunawela, P., Vishwakula, S & Lunec, J. Pattern of nucleotide variants of TP53 and
their correlation with the expression of p53 and its downstream proteins in a Sri Lankan cohort
of breast and colorectal cancer patients. BMC Cancer 20, 72 (2020). Doi:
https://doi.org/10.1186/s12885-020-6573-5

Overview of the genetic basis towards early detection of breast cancer. Breast Cancer

Publication
De Silva S, Tennekoon KH , Karunanayake EH
Publication year: 2019

De Silva S, Tennekoon KH , Karunanayake EH. Overview of the genetic basis towards early detection of breast cancer. Breast Cancer: Targets and Therapy, 2019

Nucleotide variants and protein expression of TP53 in a Sri Lankan cohort of head and neck cancer patients

Publication
Manoharan V, Karunanayake EH, Tennekoon KH, De Silva S, De Silva K, Angunawela P, Lunec J
Publication year: 2019

Manoharan V, Karunanayake EH, Tennekoon KH, De Silva S, De Silva K, Angunawela P, Lunec J. Nucleotide variants and protein expression of TP53 in a Sri Lankan cohort of head and neck cancer patients. Molecular Medicine Reports, 2019

Novel gross deletion at the GHRHR gene locus possibly mediated by Alu specific microhomology identified in a Sri Lankan patient with isolated growth hormone deficiency

Publication
Sundralingam T, Tennekoon KH, de Silva S, De Silva S, Hewage AS, Ranasinghe R
Publication year: 2018

Sundralingam T, Tennekoon KH, de Silva S, De Silva S, Hewage AS, Ranasinghe R. Novel gross deletion at the GHRHR gene locus possibly mediated by Alu specific microhomology identified in a Sri Lankan patient with isolated growth hormone deficiency. Growth Hormone & IGF Research, 2018; 42–43:94-101. Doi: https://doi.org/10.1016/j.ghir.2018.10.005

Pathogenic and likely pathogenic genetic alterations and polymorphisms in growth hormone gene (GH1) and growth hormone releasing hormone receptor gene (GHRHR) in a cohort of isolated growth hormone deficient (IGHD) children in Sri Lanka

Publication
Sundralingam T, Tennekoon KH, De Silva KSH, De Silva S, Hewage AS
Publication year: 2017

Sundralingam T, Tennekoon KH, De Silva KSH, De Silva S, Hewage AS. Pathogenic and likely pathogenic genetic alterations and polymorphisms in growth hormone gene (GH1) and growth hormone releasing hormone receptor gene (GHRHR) in a cohort of isolated growth hormone deficient (IGHD) children in Sri Lanka. Growth Hormone & IGF Research, 2017; 36: 22–29. Doi: http://dx.doi.org/10.1016/j.ghir.2017.08.006

 

Novel and reported pathogenic variants in exon 11 of BRCA2 gene in a cohort of Sri Lankan young breast cancer patients

Publication
De Silva, S, Tennekoon, KH, Dissanayake, A, De Silva K, Jayasekera L
Publication year: 2017

De Silva, S, Tennekoon, KH, Dissanayake, A, De Silva K, Jayasekera L. Novel and reported pathogenic variants in exon 11 of BRCA2 gene in a cohort of Sri Lankan young breast cancer patients. Familial Cancer. 2017; 16(3): 329–338. Doi: 10.1007/s10689-016-9962-9

pilot study on CYP21 gene deletions among a cohort of Sri Lankan children with congenital adrenal hyperplasia

Publication
Jayathilaka D K, Tennekoon K H, de Silva KSH, De Silva S
Publication year: 2017

Jayathilaka D K, Tennekoon K H, de Silva KSH, De Silva S. A pilot study on CYP21 gene deletions among a cohort of Sri Lankan children with congenital adrenal hyperplasia, Ceylon Medical Journal, 2017; 62(2); 112–113. Doi: http://doi.org/10.4038/cmj.v62i2.8479

Growth hormone releasing hormone receptor codon 72 mutation in a cohort of Sri Lankan patients with growth hormone deficiency

Publication
de Silva K S H, Tennekoon K H, Sundralingam T, Navarathne B, Hewage A S, de Silva WS, Ganihigama D, Jayasinghe H D, Muhandiram M E C
Publication year: 2016

de Silva K S H, Tennekoon K H, Sundralingam T, Navarathne B, Hewage A S, de Silva WS, Ganihigama D, Jayasinghe H D, Muhandiram M E C. Growth hormone releasing hormone receptor codon 72 mutation in a cohort of Sri Lankan patients with growth hormone deficiency. Ceylon Medical Journal. 2016; 61(1): 18–21.

Doi: http://doi.org/10.4038/cmj.v61i1.8257

Analysis of BRCA1and BRCA2 large genomic rearrangements in Sri Lankan familial breast cancer patients and at risk individuals

Publication
De Silva S, Tennekoon KH, Karunanayake EH., Amarasinghe I and Angunawela P
Publication year: 2014

De Silva S, Tennekoon KH, Karunanayake EH., Amarasinghe I and Angunawela P. Analysis of BRCA1and BRCA2 large genomic rearrangements in Sri Lankan familial breast cancer patients and at risk individuals. BMC Research Notes. 2014;7:344. Doi:10.1186/1756-0500-7-344

Novel sequence variants and common recurrent polymorphisms of BRCA2 in Sri Lankan breast cancer patients and a family with BRCA1 mutations. Experimental and Therapeutic Medicine

Publication
De Silva S, Tennekoon KH, Karunanayake EH., De Silva W, Amarasinghe I and Angunawela P.
Publication year: 2011

De Silva S, Tennekoon KH, Karunanayake EH., De Silva W, Amarasinghe I and Angunawela P. Novel sequence variants and common recurrent polymorphisms of BRCA2 in Sri Lankan breast cancer patients and a family with BRCA1 mutations. Experimental and Therapeutic Medicine. 2011; 2: 1163-1170. Doi: 10.3892/etm.2011.337