Cytotoxic and apoptotic effects of the bark of two common mango (Mangifera indica) varieties from Sri Lanka on breast and ovarian cancer cells

1. International peer reviewed articles
Meran Keshawa Ediriweera, Kamani Hemamala Tennekoon, Sameera Ranganath Samarakoon, Ira Thabrew, Dilip de Silva
Publication year: 2016

Meran Keshawa Ediriweera, Kamani Hemamala Tennekoon, Sameera Ranganath Samarakoon, Ira Thabrew, Dilip de Silva. Cytotoxic and apoptotic effects of the bark of two common mango (Mangifera indica) varieties from Sri Lanka on breast and ovarian cancer cells- British Journal of Pharmaceutical Research – 2016: 10(2): 1-7.

Anti-proliferative effect of five Sri Lankan endemic plants on breast cancer stem cells

3. Abstracts and International Conferences
Rajagopalan U, Samarakoon SR, Tennekoon KH, de Silva ED
Publication year: 2016

Rajagopalan U, Samarakoon SR, Tennekoon KH, de Silva ED. Anti-proliferative effect of five Sri Lankan endemic plants on breast cancer stem cells. 8th Annual Scientific Sessions 27st May, 2016. Institute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, Sri Lanka

Anti-proliferative and proapo-ptotic effects of govaniadine in human breast cancer (MCF-7) cells

3. Abstracts and International Conferences
Sivakumaran N, Samarakoon SR, Adhikari A, Ediriweera MK, Tennekoon KH, Thabrew I, Malavige N
Publication year: 2016

Sivakumaran N, Samarakoon SR, Adhikari A, Ediriweera MK, Tennekoon KH, Thabrew I, Malavige N. Anti-proliferative and proapo-ptotic effects of govaniadine in human breast cancer (MCF-7) cells. 8th Annual Scientific Sessions 27st May, 2016. Institute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, Sri Lanka.

Anti-filarial activity of Dipterocarpus zeylanicus: bioac-tivity guided isolation of active compounds and induction of apoptosis in filarial parasite Setaria digitata in vitro

3. Abstracts and International Conferences
Senathilake KS, Karunanayake EH, Samarakoon SR, Tennekoon KH, Adhikari A, de Silva ED
Publication year: 2016

Senathilake KS, Karunanayake EH, Samarakoon SR, Tennekoon KH, Adhikari A, de Silva ED.  Anti-filarial activity of Dipterocarpus zeylanicus: bioac-tivity guided isolation of active compounds and induction of apoptosis in filarial parasite Setaria digitata in vitro. 8th Annual Scientific Sessions 27st May, 2016. Institute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, Sri Lanka.

A study on potential anti-cancer activity of Mangifera zeylanica bark:  Evaluation of cytotoxic and apoptotic effects of the hexane extract and bioassay guided fractionation to identify phytochemical constituents

1. International peer reviewed articles
Ediriweera PMK, Tennekoon KH, Samarakoon SR, Thabrew I, de Silva ED
Publication year: 2016

Ediriweera PMK, Tennekoon KH, Samarakoon SR, Thabrew I, de Silva ED. A study on potential anti-cancer activity of Mangifera zeylanica bark:  Evaluation of cytotoxic and apoptotic effects of the hexane extract and bioassay guided fractionation to identify phytochemical constituents. Oncology letters- 2016: 11: 1335-1344.

A  molecular  phylogenetic  analysis  of  six  unknown amphibian  specimens  of  the genus  Pseudophilautus in Sri  Lanka

3. Abstracts and International Conferences
Lowe JN, Samarakoon SR, Wickramasinghe LJM, Tennekoon KH, Wickramasinghe N
Publication year: 2016

Lowe JN, Samarakoon SR, Wickramasinghe LJM, Tennekoon KH, Wickramasinghe N. A  molecular  phylogenetic  analysis  of  six  unknown amphibian  specimens  of  the genus  Pseudophilautus in Sri  Lanka. 8th Annual Scientific Sessions 27st May, 2016. Institute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, Sri Lanka.

Pseudophilautus dilmah, a new species of shrub frog (Amphibia: Anura: Rhacophoridae) from a threatened habitat Loolkandura in Sri Lanka

1. International peer reviewed articles
Wickramasinghe, L.J.M., I.N. Bandara, D.R. Vidanapathirana, K.H. Tennakoon, S.R. Samarakoon & N. Wickramasinghe
Publication year: 2015

Wickramasinghe, L.J.M., I.N. Bandara, D.R. Vidanapathirana, K.H. Tennakoon, S.R. Samarakoon & N. Wickramasinghe .Pseudophilautus dilmah, a new species of shrub frog (Amphibia: Anura: Rhacophoridae) from a threatened habitat Loolkandura in Sri Lanka. Journal of Threatened Taxa. 2015:7(5): 7089-110.

Potential Anti Carcinogenic Activity of Leaf and Bark Extracts of Campnosperma zeylanica

3. Abstracts and International Conferences
Jayarathna DDP, Tennekoon KH, Samarakoon SR, Thabrew I, Karunanayake EH, de Silva ED
Publication year: 2015

Jayarathna DDP, Tennekoon KH, Samarakoon SR, Thabrew I, Karunanayake EH, de Silva ED. Potential Anti Carcinogenic Activity of Leaf and Bark Extracts of Campnosperma zeylanica.  5th International Symposium-cum- Training Course on Molecular Medicine and Drug Research,   January, 2015. Karachi, Pakistan.

Possible potentiation of antiproliferative effect of tamoxifen in MCF-7 breast cancer cells by a bioactive fraction of mangrove plant Scyphiphora hydrophyllacea

3. Abstracts and International Conferences
De Silva OKC, Samarakoon SR, Tennekoon KH, Fernando EHN
Publication year: 2015

De Silva OKC, Samarakoon SR, Tennekoon KH, Fernando EHN. Possible potentiation of antiproliferative effect of tamoxifen in MCF-7 breast cancer cells by a bioactive fraction of mangrove plant Scyphiphora hydrophyllacea: A pilot study. 7th Annual Scientific Sessions 21st May, 2015. Institute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, Sri Lanka.

Molecular docking study of natural compounds for cancer stem cells targeted anti-cancer activity

3. Abstracts and International Conferences
Karthika M, Samarakoon SR, Tennekoon KH, Siriwardana A
Publication year: 2015

Karthika M, Samarakoon SR, Tennekoon KH, Siriwardana A. Molecular docking study of natural compounds for cancer stem cells targeted anti-cancer activity. 7th Annual Scientific Sessions 21st May, 2015. Institute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, Sri Lanka.

Modulation of Heat Shock Proteins and Apoptosis by Flueggea leucopyrus (Willd) decoction: possible mechanisms mediating cytotoxicity to three breast cancer phenotypes

1. International peer reviewed articles
Anuka S. Mendis, Ira Thabrew, Sameera R. Samarakoon and Kamani H. Tennekoon
Publication year: 2015

Anuka S. Mendis, Ira Thabrew, Sameera R. Samarakoon and Kamani H. Tennekoon. Modulation of Heat Shock Proteins and Apoptosis by Flueggea leucopyrus (Willd) decoction: possible mechanisms mediating cytotoxicity to three breast cancer phenotypes. BMC Complementary and alternative Medicine: 2015:15:404.

Microcystin LR induced cytotoxicity and apoptosis on human embryonic kidney (HEK 293) and human kidney adenocarcinoma (ACHN) cell lines

1. International peer reviewed articles
Piyathilaka M.A.P.C., Pathmalal M.M., Tennekoon K.H., Samarakoon S.R., Chanthirika S., and B.G.D.N.K. de Silva
Publication year: 2015

Piyathilaka M.A.P.C., Pathmalal M.M., Tennekoon K.H., Samarakoon S.R., Chanthirika S., and B.G.D.N.K. de Silva. Microcystin LR induced cytotoxicity and apoptosis on human embryonic kidney (HEK 293) and human kidney adenocarcinoma (ACHN) cell lines. Microbiology– 29th January 2015.

Isolation of two kaemferol glycosides from leaves of Olax zeylanica

3. Abstracts and International Conferences
Wijayabandara MDLO, Wijayabandara MDJ, de Silva ED, Choudhary I, Adhikari A, Fernando EHN, Samarakoon SR
Publication year: 2015

Wijayabandara MDLO, Wijayabandara MDJ, de Silva ED, Choudhary I, Adhikari A, Fernando EHN, Samarakoon SR. Isolation of two kaemferol glycosides from leaves of Olax zeylanica. 7th Annual Scientific Sessions 21st May, 2015. Institute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, Sri Lanka.

isolation of quercertin from the bark of Mangifera zeylanica and its cytotoxicity against MCF-7 breast cancer cells

3. Abstracts and International Conferences
Ediriweera MK, Tennekoon KH, Samarakoon SR, Thabrew I, de Silva ED, Adhikari A. M Choudhary
Publication year: 2015

Ediriweera MK, Tennekoon KH, Samarakoon SR, Thabrew I, de Silva ED, Adhikari A. M Choudhary.  isolation of quercertin from the bark of Mangifera zeylanica and its cytotoxicity against MCF-7 breast cancer cells. 7th Annual Scientific Sessions 21st May, 2015. Institute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, Sri Lanka.

Isolation of lupeol an anti-carcinogenic compound from the leaves of Connarus championni

3. Abstracts and International Conferences
Jayarathna DDP, Tennekoon KH, Samarakoon SR, Thabrew I, Karunanayake EH, de Silva ED Adhikar A
Publication year: 2015

Jayarathna DDP, Tennekoon KH, Samarakoon SR, Thabrew I, Karunanayake EH, de Silva ED Adhikar A. Isolation of lupeol an anti-carcinogenic compound from the leaves of Connarus championni. 7th Annual Scientific Sessions 21st May, 2015. Institute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, Sri Lanka.

Isolation of Hopenone-I from the Leaves of Mangrove Plant Scyphiphora hydrophyllacea and Its Cytotoxic Properties

1. International peer reviewed articles
Sameera Ranganath Samarakoon*, Nisala Fernando, Meran Keshawa Ediriweera, Achyut Adhikari, Lakshan Wijayabandara, E. Dilip de Silva and Kamani Hemamala Tennekoon
Publication year: 2015

Sameera Ranganath Samarakoon*, Nisala Fernando, Meran Keshawa Ediriweera, Achyut Adhikari, Lakshan Wijayabandara, E. Dilip de Silva and Kamani Hemamala Tennekoon. Isolation of Hopenone-I from the Leaves of Mangrove Plant Scyphiphora hydrophyllacea and Its Cytotoxic Properties. British Journal of Pharmaceutical Research. published online 29th December 2015: 10(1): 1-6.

Enhanced in vitro anti cancer efficacy of doxorubicin loaded chitosan-alginate nanoparticles on breast cancer (MCF-7) cells

3. Abstracts and International Conferences
Katuwavila KANP, Perera ADLC, Samarakoon SR, Karunaratne V  and Karunaratne DN
Publication year: 2015

Katuwavila KANP, Perera ADLC, Samarakoon SR, Karunaratne V  and Karunaratne DN. Enhanced in vitro anti cancer efficacy of doxorubicin loaded chitosan-alginate nanoparticles on breast cancer (MCF-7) cells. 7th Annual Scientific Sessions 21st May, 2015. Institute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, Sri Lanka.

DNA barcoding of a novel amphibian species from the Central highlands of Sri Lanka

3. Abstracts and International Conferences
Wickramasinghe N, Tennakoon KH, Samarakoon SR, Bandara IN, Vidanapathirana DR,Wickramasinghe LJM
Publication year: 2015

Wickramasinghe N, Tennakoon KH, Samarakoon SR, Bandara IN, Vidanapathirana DR,Wickramasinghe LJM. DNA barcoding of a novel amphibian species from the Central highlands of Sri Lanka. 7th Annual Scientific Sessions 21st May, 2015. Institute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, Sri Lanka

Cytotoxic effects of hopenone-I isolated from leaves of a mangrove plant Scyphiphora hydrophyllacea on breast cancer (MCF-7) Cells

3. Abstracts and International Conferences
Fernando EHN, Samarakoon SR, de Silva ED,Tennekoon KH2, Ediriweera PMK, Thabrew I, Adhikari A, Choudhary I
Publication year: 2015

Fernando EHN, Samarakoon SR, de Silva ED,Tennekoon KH2, Ediriweera PMK, Thabrew I, Adhikari A, Choudhary I. Cytotoxic effects of hopenone-I isolated from leaves of a mangrove plant Scyphiphora hydrophyllacea on breast cancer (MCF-7) Cells. 7th Annual Scientific Sessions 21st May, 2015. Institute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, Sri Lanka.

Cytotoxic and apoptotic potential of Sri Lankan endemic mango (Mangifera zeylanica) and common mango (Mangifera indica)

3. Abstracts and International Conferences
Ediriweera PMK, Tennekoon KH, Samarakoon SR, Thabrew I, de Silva ED
Publication year: 2015

Ediriweera PMK, Tennekoon KH, Samarakoon SR, Thabrew I, de Silva ED. Cytotoxic and apoptotic potential of Sri Lankan endemic mango (Mangifera zeylanica) and common mango (Mangifera indica). TWAS-ROCASA Young Scientists Conference on Nanoscience & Nanomaterials. India. Feb 18-20, 2015.

Antifilarial and antioxidant activities of Calotrophis gigantea and Zingiber cylindricum

3. Abstracts and International Conferences
Senathilake KS, Samarakoon SR, Karunanayake EH,Tennekoon KH, De Silva ED
Publication year: 2015

Senathilake KS, Samarakoon SR, Karunanayake EH,Tennekoon KH, De Silva ED.Antifilarial and antioxidant activities of Calotrophis gigantea and Zingiber cylindricum, 5th International Symposium-cum-Training course on Molecular medicine and drug research; 2015 Jan 12-15:Karachi,Pakistan.OP 77.

A comparison of cytotoxic effects of Vernonia zeylanica (L.) Less fractions on breast cancer phenotypes

3. Abstracts and International Conferences
Mendis AS, Thabrew MI, Samarakoon S, Tennekoon KH
Publication year: 2015

Mendis AS, Thabrew MI, Samarakoon S, Tennekoon KH. A comparison of cytotoxic effects of Vernonia zeylanica (L.) Less fractions on breast cancer phenotypes. 7th Annual Scientific Sessions 21st May, 2015. Institute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, Sri Lanka.

A comparison of cytotoxic effects of Flueggea leucopyrus (willd.) fractions on three brest cancer phenotypes

3. Abstracts and International Conferences
Mendis AS, Thabrew MI, Samarakoon S and Tennekoon KH
Publication year: 2015

Mendis AS, Thabrew MI, Samarakoon S and Tennekoon KH. A comparison of cytotoxic effects of Flueggea leucopyrus (willd.) fractions on three brest cancer phenotypes. TWAS-ROCASA Young Scientists Conference on Nanoscience & Nanomaterials. India. Feb 18-20, 2015.

Screening of Selected Medicinal Plants for Possible Cytotoxic Effects on Breast Cancer

3. Abstracts and International Conferences
Jayarathna DDP, Tennekoon KH, Samarakoon SR, Thabrew I, Karunanayake EH, Shanmuganathan C, de Silva ED
Publication year: 2014

Jayarathna DDP, Tennekoon KH, Samarakoon SR, Thabrew I, Karunanayake EH, Shanmuganathan C, de Silva ED. Screening of Selected Medicinal Plants for Possible Cytotoxic Effects on Breast Cancer. 2nd international conference on frontiers of Molecular Life Sciences. 11th -12th September, 2014. Colombo.

Screening of five medicinal plants for phenotype specific cytotoxic effects on breast cancer

3. Abstracts and International Conferences
D.D.P. Jayarathna, S.R Samarakoon, K. H Tennekoon, I. Thabrew, E. H.Karunanayake, E D de Silva
Publication year: 2014

D.D.P. Jayarathna, S.R Samarakoon, K. H Tennekoon, I. Thabrew, E. H.Karunanayake, E D de Silva. Screening of five medicinal plants for phenotype specific cytotoxic effects on breast cancer. Annual Scientific Sessions 2014 of the Sri Lanka Medical Association (SLMA)- July, 2014.

n silico characterization of a RNA binding protein of cattle filarial parasite Setaria digitata

1. International peer reviewed articles
Nirupa Nagaratnam, Eric H Karunanayake, Kamani H Tennekoon, Sameera R Samarakoon, Karthika Mayan
Publication year: 2014

Nirupa Nagaratnam, Eric H Karunanayake, Kamani H Tennekoon, Sameera R Samarakoon, Karthika Mayan. In silico characterization of a RNA binding protein of cattle filarial parasite Setaria digitata. Bioinformation- 2014.10(8): 521-516.

In vitro anti-hepatocarcinogenic properties of a mangrove plant Scyphiphora hydrophyllacea

3. Abstracts and International Conferences
Samarakoon SR, Chanthirika S, Tennekoon KH, Thabrew MI, Ediriweera PMK, de Silva ED
Publication year: 2014

Samarakoon SR, Chanthirika S, Tennekoon KH, Thabrew MI, Ediriweera PMK, de Silva ED. In vitro anti-hepatocarcinogenic properties of a mangrove plant Scyphiphora hydrophyllacea. 2nd international conference on frontiers of Molecular Life Sciences.  11th -12th September, 2014. Colombo.

In silico characterization of RNA binding protein motif of filarial parasite Setaria digitata

3. Abstracts and International Conferences
Nirupa Nagaratnam, Eric H Karunanayake, Kamani H Tennekoon, Sameera R Samarakoon, Karthika Mayan
Publication year: 2014

Nirupa Nagaratnam, Eric H Karunanayake, Kamani H Tennekoon, Sameera R Samarakoon, Karthika Mayan. In silico characterization of RNA binding protein motif of filarial parasite Setaria digitata. 2nd international conference on frontiers of Molecular Life Sciences. 11th -12th September, 2014. Colombo.

Hexane extract of Mangifera zeylanica bark exhibits cytotoxic activity through induction of apoptosis in triple negative breast cancer cells (MDA-MB-231) and ovarian cancer cells (SKOV3)

3. Abstracts and International Conferences
Ediriweera PMK, Tennekoon KH, Samarakoon SR, Thabrew I, de Silva ED
Publication year: 2014

Ediriweera PMK, Tennekoon KH, Samarakoon SR, Thabrew I, de Silva ED. Hexane extract of Mangifera zeylanica bark exhibits cytotoxic activity through induction of apoptosis in triple negative breast cancer cells (MDA-MB-231) and ovarian cancer cells (SKOV3). 2nd international conference on frontiers of Molecular Life Sciences. 11th -12th September, 2014. Colombo.

Effects of Flueggea leucopyrus (Willd.) Decoction on HSP 70 Expression and Apoptosis in Triple Negative Breast Cancer Phenotype MDA-MB-231

3. Abstracts and International Conferences
Mendis AS, Thabrew MI, Samarakoon S and Tennekoon KH
Publication year: 2014

Mendis AS, Thabrew MI, Samarakoon S and Tennekoon KH. Effects of Flueggea leucopyrus (Willd.) Decoction on HSP 70 Expression and Apoptosis in Triple Negative Breast Cancer Phenotype MDA-MB-231. 2nd international conference on frontiers of Molecular Life Sciences.  11th -12th September, 2014. Colombo.