ncreased serum NO levels in severe leptospirosis patients in Sri Lanka

Oral Presentations at National Conferences & Symposia
Kalugalage TL, Vithanage TDP, Somaratne P, De Silva HJ, Rajapakse S, Handunnetti SM
Publication year: 2011

Kalugalage TL, Vithanage TDP, Somaratne P, De Silva HJ, Rajapakse S, Handunnetti SM. Increased serum NO levels in severe leptospirosis patients in Sri Lanka. Proceedings of the 31stAnnual Sessions of the IOB-SL, 2011; pp 49

Inhibition of pro-inflammatory cytokine secretion by human mononuclear cells and phagocytic activity of human neutrophils by aqueous leaf extract of Vitex negundo

Oral Presentations at National Conferences & Symposia
Kariyawasam KWJC, Sirisena PDNN, De Silva ED, Ratnasooriya WD and Handunnetti SM
Publication year: 2011

Kariyawasam KWJC, Sirisena PDNN, De Silva ED, Ratnasooriya WD and Handunnetti SM. Inhibition of pro-inflammatory cytokine secretion by human mononuclear cells and phagocytic activity of human neutrophils by aqueous leaf extract of Vitex negundo (Abstract 415/D).  Proceedings of the 67th Annual Sessions of the SLAAS, 2011; pp 57

Anti-inflammatory activity of dried flower extracts of Aegle marmelos in Wistar rats

Oral Presentations at National Conferences & Symposia
Kumari KDKP, Handunnetti SM, Suresh TS, Samarasinghe K
Publication year: 2011

Kumari KDKP, Handunnetti SM, Suresh TS, Samarasinghe K. Anti-inflammatory activity of dried flower extracts of Aegle marmelos in Wistar rats. Proceedings of the 4thAnnual Scientific Sessions of the IBMBB, University of Colombo, 5th May 2011; pp 24

Modulation of human neutrophil functions by aqueous and methanolic leaf extracts of Ixora coccinea

Oral Presentations at National Conferences & Symposia
Wickremesinghe NKRD, Kumara RR, De Silva DE, Ratnasooriya WD and Handunnetti SM
Publication year: 2010

Wickremesinghe NKRD, Kumara RR, De Silva DE, Ratnasooriya WD and Handunnetti SM. Modulation of human neutrophil functions by aqueous and methanolic leaf extracts of Ixora coccinea. Proceedings of the 5th Biennial Sessions of the AISSL, 30th July, 2010; pp 19

Immunity induced by live malarial sporozoites under chloroquine treatment is strain specific

Oral Presentations at National Conferences & Symposia
Wijayalath AWWK, Cheeseman S, Rajakaruna J, Weerasinghe S, Kapliananda GMG, Gamage K, Perera K,  Handunnetti SM, Carter Rand Pathirana PPSL
Publication year: 2010

Wijayalath AWWK, Cheeseman S, Rajakaruna J, Weerasinghe S, Kapliananda GMG, Gamage K, Perera K,  Handunnetti SM, Carter Rand Pathirana PPSL.  Immunity induced by live malarial sporozoites under chloroquine treatment is strain specific. Proceedings of the Research Symposium/Faculty of Medicine, 2010, pp 94

Strain-specific protective immunity to pre-erythrocytic stages of malaria parasite, Plasmodium cynomolgi

Oral Presentations at National Conferences & Symposia
Wijayalath AWWK, Cheeseman S, Rajakaruna J, Weerasinghe S, Kapliananda GMG, Gamage K, Perera K,  Handunnetti SM, Carter R and Pathirana PPSL
Publication year: 2009

Wijayalath AWWK, Cheeseman S, Rajakaruna J, Weerasinghe S, Kapliananda GMG, Gamage K, Perera K,  Handunnetti SM, Carter R and Pathirana PPSL.  Strain-specific protective immunity to pre-erythrocytic stages of malaria parasite, Plasmodium cynomolgi. Proceedings of the 4th Biennial Sessions of the AISSL, 10th July, 2009; pp 17

Effect of aqueous leaf extracts of Vitex negundo on nitric oxide production and secretion of TNF-α by human leukocytes

Oral Presentations at National Conferences & Symposia
Kariyawasam KWJC, Nanayakkara HLC, Kumara RR, De Silva ED, Ratnasooriya WD and Handunnetti SM
Publication year: 2009

Kariyawasam KWJC, Nanayakkara HLC, Kumara RR, De Silva ED, Ratnasooriya WD and Handunnetti SM. Effect of aqueous leaf extracts of Vitex negundo on nitric oxide production and secretion of TNF-α by human leukocytes. Proceedings of the 4th Biennial Sessions of the AISSL, 10th July, 2009; pp 20

Effect of aqueous extracts of Anisomeles indica, Caesalpinia bonduc and Toddalia asiatica on the secretion of pro-inflammatory cytokines by human mononuclear cells

Oral Presentations at National Conferences & Symposia
Nanayakkara HLC, Kariyawasam KWJC, Kumara RR, De Silva ED, Ratnasooriya WD and Handunnetti SM
Publication year: 2009

Nanayakkara HLC, Kariyawasam KWJC, Kumara RR, De Silva ED, Ratnasooriya WD and Handunnetti SM. Effect of aqueous extracts of Anisomeles indica, Caesalpinia bonduc and Toddalia asiatica on the secretion of pro-inflammatory cytokines by human mononuclear cells. Proceedings of the 4th Biennial Sessions of the AISSL, 10th July, 2009; pp 19.

 

Anti inflammatory activity of leafs of Ixora coccinea: Use of in vitro and in vivo assays for activity-directed fractionation

Oral Presentations at National Conferences & Symposia
Kumara RR, Nanayakkara AA, Deraniyagala SA, Ratnasooriya WD and Handunnetti SM
Publication year: 2008

Kumara RR, Nanayakkara AA, Deraniyagala SA, Ratnasooriya WD and Handunnetti SM.  Anti inflammatory activity of leafs of Ixora coccinea: Use of in vitro and in vivo assays for activity-directed fractionation.  Proceedings of the 3rd Annual Scientific Sessions of the IBMBB, University of Colombo, 25th April 2008; pp 22

Patterns of anti-PvRII IgG and IgG isotypes to Plasmodium vivax Duffy Binding Protein in Sri Lanka

Oral Presentations at National Conferences & Symposia
Premaratne PH, Dias KVGS, Handunnetti SM, Yazdani S, Chitins C and Udagama-Randeniya PV
Publication year: 2007

Premaratne PH, Dias KVGS, Handunnetti SM, Yazdani S, Chitins C and Udagama-Randeniya PV. Patterns of anti-PvRII IgG and IgG isotypes to Plasmodium vivax Duffy Binding Protein in Sri Lanka (Abstract 018/A).  Proceedings of the 63rdAnnual Sessions of the SLAAS, December 2007; pp 17-18

Natural antibody response to Plasmodium vivax merozoite surface proteins-1 and -4 in Sri Lanka

Oral Presentations at National Conferences & Symposia
Dissanayake MU, Dias KVGS, Premaratne PH, Wickramarachchi WTA, Handunnetti SM, Longacre S and Udagama-Randeniya PV
Publication year: 2007

Dissanayake MU, Dias KVGS, Premaratne PH, Wickramarachchi WTA, Handunnetti SM, Longacre S and Udagama-Randeniya PV. Natural antibody response to Plasmodium vivax merozoite surface proteins-1 and -4 in Sri Lanka (Abstract 13).  Proceedings of the 2nd Annual Scientific Sessions of the IBMBB, University of Colombo, 27th April 2007; 18

Anti-inflammatory activity of methanol leaf extract of Ixora coccinea in rats

Oral Presentations at National Conferences & Symposia
Kumara RR, Nanayakkara AA, Deraniyagala SA and Ratnasooriya WD and Handunnetti SM.
Publication year: 2007

Kumara RR, Nanayakkara AA, Deraniyagala SA and Ratnasooriya WD and Handunnetti SM. Anti-inflammatory activity of methanol leaf extract of Ixora coccinea in rats (Abstract 7).  Proceedings of 2nd Annual Scientific Sessions of the IBMBB, University of Colombo, 27th April 2007; 12

Studies on strain-specific protective immunity in malaria using Plasmodium cynomolgi /toque monkey (Macaca sinica) model

Oral Presentations at National Conferences & Symposia
Wijayalath AWWK, Cheeseman S, Rajakaruna J, Gamage K, Perera K, Perera KLRL, Carter R,  Handunnetti SM and Pathirana PPSL
Publication year: 2006

Wijayalath AWWK, Cheeseman S, Rajakaruna J, Gamage K, Perera K, Perera KLRL, Carter R,  Handunnetti SM and Pathirana PPSL.  Studies on strain-specific protective immunity in malaria using Plasmodium cynomolgi /toque monkey (Macaca sinica) model. Proceedings of the 3rd Annual Sessions of the AISSL, 17th November, 2006;B1, pp 24

Specificity of the antibody response to conformational and linear epitopes of Plasmodium vivax Duffy binding protein in Sri Lanka

Oral Presentations at National Conferences & Symposia
Premaratne PH, Dias KVGS, Wickramarachchi WTA, Perera KLRL, Bandara S, Chitnis C, Yasdani S, Handunnetti SM and Udagama-Randeniya PV
Publication year: 2006

Premaratne PH, Dias KVGS, Wickramarachchi WTA, Perera KLRL, Bandara S, Chitnis C, Yasdani S, Handunnetti SM and Udagama-Randeniya PV.  Specificity of the antibody response to conformational and linear epitopes of Plasmodium vivax Duffy binding protein in Sri Lanka. Proceedings of the 3rd Annual Sessions of the AISSL 17th November, 2006; B2, pp 25-26

Investigations on anti-inflammatory potential and chemical constituents of Ixora coccinea, Vitex negundo and Alpinia calcarata

Oral Presentations at National Conferences & Symposia
Kumara RR, Handunnetti SM, Deraniyagala SA and Ratnasooriya WD
Publication year: 2006

Kumara RR, Handunnetti SM, Deraniyagala SA and Ratnasooriya WD. Investigations on anti-inflammatory potential and chemical constituents of Ixora coccinea, Vitex negundo and Alpinia calcarata. Proceedings of the 1st Annual Scientific Sessions of the Institute of Biochemistry, Molecular Biology and Biotechnology (IBMBB), University of Colombo, 28th April 2006; pp 15

Inhibition of peritoneal phagocytic cell infiltration in rats by aqueous extracts Vitex negundo, Ixora coccinea and Alpinia calcarata

Oral Presentations at National Conferences & Symposia
de Silva SSP, Kumara RR, Deraniyagala SD, Ratnasooriya WD, Handunnetti SM
Publication year: 2006

de Silva SSP, Kumara RR, Deraniyagala SD, Ratnasooriya WD, Handunnetti SM. Inhibition of peritoneal phagocytic cell infiltration in rats by aqueous extracts Vitex negundo, Ixora coccinea and Alpinia calcarata.Proceedings of the 3rd Annual Sessions of the AISSL, 17th November, 2006; B7, pp 34

IgM antibody response to Plasmodium vivax Duffy binding protein in Sri Lanka

Oral Presentations at National Conferences & Symposia
Premaratne PH, Wickramarachchi WTA, Perera KLRL, Bandara S, Chitnis C, Yasdani S, Handunnetti SM and Udagama-Randeniya PV
Publication year: 2006

Premaratne PH, Wickramarachchi WTA, Perera KLRL, Bandara S, Chitnis C, Yasdani S, Handunnetti SM and Udagama-Randeniya PV.  IgM antibody response to Plasmodium vivax Duffy binding protein in Sri Lanka. Proceedings of the 3rd Biennial Sessions of the AISSL, 17th November, 2006; B3, pp 27-28

Human single nucleotide polymorphisms and falciparum malaria in Sri Lanka

Oral Presentations at National Conferences & Symposia
Munasighe RA, Silva A, Wickremesinghe AR, Premawansa G, Handunnetti S, Kwaitkowski D, and Premawansa S
Publication year: 2006

Munasighe RA, Silva A, Wickremesinghe AR, Premawansa G, Handunnetti S, Kwaitkowski D, and Premawansa S. Human single nucleotide polymorphisms and falciparum malaria in Sri Lanka. Proceedings of the 3rd Biennial Sessions of the AISSL, 17th November, 2006; B4, pp 29-30

Genetic complexity of Plasmodium vivax infections in Sri Lanka

Oral Presentations at National Conferences & Symposia
Wickramarachchi WTA, Premaratne PH, Dias KVGS, Handunnetti SM, Gunasekera AM, Wirth DF and Udagama-Randeniya PV
Publication year: 2006

Wickramarachchi WTA, Premaratne PH, Dias KVGS, Handunnetti SM, Gunasekera AM, Wirth DF and Udagama-Randeniya PV. Genetic complexity of Plasmodium vivax infections in Sri Lanka (Abstract 004/A). Proceedings of the 62nd Annual Sessions of the SLAAS, 2006; pp 3.

Role of spleen in modulating cytoadherence properties of Plasmodium falciparum: Comparison of parasite isolates from splenectomized patient and spleen intact patients

Oral Presentations at National Conferences & Symposia
Munasighe RA, Ileperuma M, Kapilananda GM, Premawansa G, Handunnetti SM and Premawansa S
Publication year: 2004

Munasighe RA, Ileperuma M, Kapilananda GM, Premawansa G, Handunnetti SM and Premawansa S. Role of spleen in modulating cytoadherence properties of Plasmodium falciparum: Comparison of parasite isolates from splenectomized patient and spleen intact patients. Proceedings of the 2nd Biennial Sessions of the AISSL, 19thNovember, 2004; B9

Patterns of IgG1 and IgG3 isotype responses to Duffy Binding Protein of Palsmodium vivax in Sri Lanka

Oral Presentations at National Conferences & Symposia
Premaratne PH, Wickramarachchi WTA, Perera KLRL, Bandara S, Chitnis C, Yazdani S, Handunnetti SM and Udagma-Randeniya PV
Publication year: 2004

Premaratne PH, Wickramarachchi WTA, Perera KLRL, Bandara S, Chitnis C, Yazdani S, Handunnetti SM and Udagma-Randeniya PV. Patterns of IgG1 and IgG3 isotype responses to Duffy Binding Protein of Palsmodium vivax in Sri Lanka, Proceedings of the Joint Academic Sessions of the Faculties of Science & Medicine, 25thJune, 2004; University of Colombo, Sri Lanka, pp 30

Inhibitory effects on parasite cytoadherence by sera from Plasmodium falciparum-infected Sri Lankan patients

Oral Presentations at National Conferences & Symposia
Perera IC, Pathirana PPSL, Kapilananda GM, Munasinghe RA, Handunnetti SM and Premawansa S
Publication year: 2004

Perera IC, Pathirana PPSL, Kapilananda GM, Munasinghe RA, Handunnetti SM and Premawansa S. Inhibitory effects on parasite cytoadherence by sera from Plasmodium falciparum-infected Sri Lankan patients. Proceedings of the 60thAnnual Sessions of the SLAAS, 2004; pp 28

mmunogenicity and protective efficacy of two new vaccine formulations based on merozoite surface protein-1 of Plasmodium cynomolgi

Oral Presentations at National Conferences & Symposia
Handunnetti SM, Weerasinghe S, Amaratunga C, Rajakaruna J, Perera KLRL, Perera K, Gamage K, Holm I, Longacre S
Publication year: 2004

Handunnetti SM, Weerasinghe S, Amaratunga C, Rajakaruna J, Perera KLRL, Perera K, Gamage K, Holm I, Longacre S. Immunogenicity and protective efficacy of two new vaccine formulations based on merozoite surface protein-1 of Plasmodium cynomolgi. Proceedings of the Joint Academic Sessions of the Faculties of Science & Medicine, 25thJune, 2004; University of Colombo, Sri Lanka, pp 15

Human antibody responses to Palsmodium vivax Duffy Binding Protein in Sri Lanka

Oral Presentations at National Conferences & Symposia
Wansadhipathi NK, Wickramarachchi WTA, PereraKLRL, Bandara S, Chitnis C, Yazdani S, Handunnetti SM and Udagma-Randeniya PV
Publication year: 2004

Wansadhipathi NK, Wickramarachchi WTA, PereraKLRL, Bandara S, Chitnis C, Yazdani S, Handunnetti SM and Udagma-Randeniya PV. Human antibody responses to Palsmodium vivax Duffy Binding Protein in Sri Lanka, Proceedings of the Joint Academic Sessions of the Faculties of Science & Medicine, 25thJune, 2004; University of Colombo, Sri Lanka, pp 29

Heterogeneity of isotype specific antibody responses against Plasmodium vivax asexual blood stage antigens in Sri Lanka

Oral Presentations at National Conferences & Symposia
Wickramarachchi WTA, Premaratne PH, Perera KLRL, Bandara S, Longacre S, Kocken C, Thomas A, Handunnetti SM and Randeniya PV
Publication year: 2004

Wickramarachchi WTA, Premaratne PH, Perera KLRL, Bandara S, Longacre S, Kocken C, Thomas A, Handunnetti SM and Randeniya PV. Heterogeneity of isotype specific antibody responses against Plasmodium vivax asexual blood stage antigens in Sri Lanka. Proceedings of the 24th Annual Sessions of the IOB-SL, 6th October, 2004, pp 5

Development of real-time quantitative PCR (RTQ-PCR) methods for analysis of vaccine protection using the Plasmodium cynomolgi malaria model

Oral Presentations at National Conferences & Symposia
Pathirana PPSL, Liselotte W, Weerasinghe S, Longacre S, Suerwein R, Handunnetti SM, Hermeson CC
Publication year: 2004

Pathirana PPSL, Liselotte W, Weerasinghe S, Longacre S, Suerwein R, Handunnetti SM, Hermeson CC. Development of real-time quantitative PCR (RTQ-PCR) methods for analysis of vaccine protection using the Plasmodium cynomolgi malaria model. Proceedings of the Joint Academic Sessions of the Faculties of Science & Medicine, 25thJune, 2004; University of Colombo, Sri Lanka, pp 16

Development of quantitative real-time PCR method for analysis of vaccine protection using Plasmoium cynomolgi malaria model

Oral Presentations at National Conferences & Symposia
Pathirana PPSL, Walters L, Weerasinghe S, Logacre S, Suerwein R, Handunnetti SM, Hermsen CC
Publication year: 2004

Pathirana PPSL, Walters L, Weerasinghe S, Logacre S, Suerwein R, Handunnetti SM, Hermsen CC. Development of quantitative real-time PCR method for analysis of vaccine protection using Plasmoium cynomolgi malaria model. Proceedings of the 2nd Biennial Sessions of the AISSL, 19thNovember, 2004; B3

Cytoadherence and its inhibition of Plasmodium falciparum parasites from Sri Lankan patients to endothelial receptors, CD36 and ICAM-1

Oral Presentations at National Conferences & Symposia
Perera IC, Munasinghe RA, Pathirana S, Perera MK, Ileperuma M, Nadaraja T, Kapilananda GM, Handunnetti SM and Premawansa S
Publication year: 2004

Perera IC, Munasinghe RA, Pathirana S, Perera MK, Ileperuma M, Nadaraja T, Kapilananda GM, Handunnetti SM and Premawansa S. Cytoadherence and its inhibition of Plasmodium falciparum parasites from Sri Lankan patients to endothelial receptors, CD36 and ICAM-1.  Proceedings of the 2nd Biennial Sessions of the AISSL, 19thNovember, 2004; B8

orrelates of protection for MSP1p19 based pre-clinical trials

Oral Presentations at National Conferences & Symposia
Amaratunga C, Perera KLRL, S Weerasinghe, Perera K, Holm I,Longacre S and Handunnetti SM
Publication year: 2004

Amaratunga C, Perera KLRL, S Weerasinghe, Perera K, Holm I,Longacre S and Handunnetti SM. Correlates of protection for MSP1p19 based pre-clinical trials.  Proceedings of the 2nd Biennial Sessions of the Allergy and Immunology Society, Sri Lanka (AISSL), 19thNovember, 2004; B6

Comparison of two different recombinant proteins representing region II of the Duffy Binding Protein of Plasmodium vivax by assaying for natural Antibodies

Oral Presentations at National Conferences & Symposia
Premaratne PH, Wansadhipathi NK, Wickramarachchi WTA, Perera KLRL, Bandara, Handunnetti SM and Udagama-Randeniya PV
Publication year: 2004

Premaratne PH, Wansadhipathi NK, Wickramarachchi WTA, Perera KLRL, Bandara, Handunnetti SM and Udagama-Randeniya PV. Comparison of two different recombinant proteins representing region II of the Duffy Binding Protein of Plasmodium vivax by assaying for natural Antibodies. Proceedings of the 2nd Biennial Sessions of the AISSL, 19thNovember, 2004; B4