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Utility of pf/pan RDT for diagnosis in the phase of prevention of re-establishment of malaria in Sri Lanka

Publications in Peer-reviewed indexed Journals
Kumudunayana Gunasekera, Risintha Premaratne, Jagathpriya Weerasena, Sunil Premawansa, Shiroma Handunnetti, Deepika Fernando
Publication year: 2018

Kumudunayana Gunasekera, Risintha Premaratne, Jagathpriya Weerasena, Sunil Premawansa, Shiroma Handunnetti, Deepika Fernando. Utility of pf/pan RDT for diagnosis in the phase of prevention of re-establishment of malaria in Sri Lanka. Pathogens and Global Health, 2018. Oct;112(7):360-367. doi: 10.1080/20477724.2018.1536855. Epub 2018 Oct 24

Use of molecular makers for monitoring therapeutic efficacy of malaria patients in the malaria prevention of re-introduction phase in Sri Lanka

Poster Presentations at National Conferences & Symposia
Gunasekera WMKT de AW, Premaratne RG, Weerasena OVDSJ, Handunnetti SM, Premawansa S, Fernando SD
Publication year: 2018

Gunasekera WMKT de AW, Premaratne RG, Weerasena OVDSJ, Handunnetti SM, Premawansa S, Fernando SD. Use of molecular makers for monitoring therapeutic efficacy of malaria patients in the malaria prevention of re-introduction phase in Sri Lanka. Proceeding of the 74th Annual Session of SLAAS, pp: 105

Use of allergenic cross-reactivity between Apis dorsata Fabricius (Giant Asian Honeybee) and Apis mellifera Linnaeus (Western Honeybee) for diagnosis of A. dorsata venom allergy. (OP07)

Oral Presentations at National Conferences & Symposia
Gunasekara DLPE, Handunnetti SM, Premawansa S, Witharana EWRA, Dasanayake WMDK, Ratnayake IP, Seneviratne SL, Dias RKS, Premakumara GAS, De Silva R
Publication year: 2018

Gunasekara DLPE, Handunnetti SM, Premawansa S, Witharana EWRA, Dasanayake WMDK, Ratnayake IP, Seneviratne SL, Dias RKS, Premakumara GAS, De Silva R. Use of allergenic cross-reactivity between Apis dorsata Fabricius (Giant Asian Honeybee) and Apis mellifera Linnaeus (Western Honeybee) for diagnosis of A. dorsata venom allergy. (OP07). Proceeding of the 10th Annual Scientific Sessions of IBMBB, University of Colombo. 21st November 2018, pp: 21

The effect of antimicrobial agents on inflammatory cytokines in acute leptospirosis

Publications in Peer-reviewed indexed Journals
Narmada Fernando, Rajiva de Silva, Shiroma M Handunnetti, Lilani Karunanayake, Nipun Lakshitha De Silva, H Janaka de Silva, Senaka Rajapakse, Sunil Premawansa
Publication year: 2018

Narmada Fernando, Rajiva de Silva, Shiroma M Handunnetti, Lilani Karunanayake, Nipun Lakshitha De Silva, H Janaka de Silva, Senaka Rajapakse, Sunil Premawansa. The effect of antimicrobial agents on inflammatory cytokines in acute leptospirosis. Antimicrobial Agents and Chemotherapy. May 2018; 62(5) e02312-17. r62:e02312-17.https://doi .org/10.1128/ AAC.02312-17

Studies on in vitro anti-inflammatory potential and phytoconstituents of ethanol bark extract of Flacourtia indica. (OP14)

Oral Presentations at National Conferences & Symposia
Perera HDSM, Samarasekera R, Handunnetti SM, Weerasena OVDSJ, Jabeen A, Choudhary MI
Publication year: 2018

Perera HDSM, Samarasekera R, Handunnetti SM, Weerasena OVDSJ, Jabeen A, Choudhary MI. Studies on in vitro anti-inflammatory potential and phytoconstituents of ethanol bark extract of Flacourtia indica. (OP14). Proceeding of the 10th Annual Scientific Sessions of IBMBB, University of Colombo. 21st November 2018, pp: 28

Serological prevalence and determination of cut-off levels of Leptospirosis IgM and IgG in relation to Patoc I strain of Leptospira biflexa in a cohort of individuals from a high prevalence region in Sri Lanka

Poster Presentations at National Conferences & Symposia
Balaji K, Weeratunga PN, Ramchandani KC, Wijerathne PBP, Sam G, Fernando N, Handunnetti SM, Fernando SD, Rajapakse S
Publication year: 2018

Balaji K, Weeratunga PN, Ramchandani KC, Wijerathne PBP, Sam G, Fernando N, Handunnetti SM, Fernando SD, Rajapakse S. Serological prevalence and determination of cut-off levels of Leptospirosis IgM and IgG in relation to Patoc I strain of Leptospira biflexa in a cohort of individuals from a high prevalence region in Sri Lanka. Proceeding of the 10th Annual Scientific Sessions of IBMBB, University of Colombo. 21st November 2018, pp: 39

Reactivity of population samples from Colombo district for anti-leptospiral antibodies in microscopic agglutination test

Poster Presentations at National Conferences & Symposia
Balaji K, Weeratunga PN, Ramchandani KC, Wijerathne PBP, Sam G, Fernando N, Handunnetti SM, Fernando SD, Rajapakse S
Publication year: 2018

Balaji K, Weeratunga PN, Ramchandani KC, Wijerathne PBP, Sam G, Fernando N, Handunnetti SM, Fernando SD, Rajapakse S.   Reactivity of population samples from Colombo district for anti-leptospiral antibodies in microscopic agglutination test. Proceeding of the 10th Annual Scientific Sessions of IBMBB, University of Colombo. 21st November 2018, pp: 38

Preliminary study on pollen records during South-West monsoon in selected locations in Sri Lanka and direct effect of pollen on basophil degranulation

Poster Presentations at National Conferences & Symposia
Guruge BMA, Ishaka GKD, Handunnetti SM, de Silva R, Premawansa S, Premathilake TR
Publication year: 2018

Guruge BMA, Ishaka GKD, Handunnetti SM, de Silva R, Premawansa S, Premathilake TR. Preliminary study on pollen records during South-West monsoon in selected locations in Sri Lanka and direct effect of pollen on basophil degranulation. Proceeding of the 10th Annual Scientific Sessions of IBMBB, University of Colombo. 21st November 2018, pp: 34

Preliminary study on CTLA-4 gene mutations in Inflammatory Bowel Disease in Sri Lanka

Poster Presentations at National Conferences & Symposia
Hewagama AHS, Pathirana SL, Handunnetti SM, Seneviratne S
Publication year: 2018

Hewagama AHS, Pathirana SL, Handunnetti SM, Seneviratne S. Preliminary study on CTLA-4 gene mutations in Inflammatory Bowel Disease in Sri Lanka. Proceeding of the 10th Annual Scientific Sessions of IBMBB, University of Colombo. 21st November 2018, pp: 31

Preliminary study on Chronic granulomatous disease in Sri Lanka

Publications in Peer-reviewed indexed Journals
Fernando SJA, Faiz NM, Handunnetti SM, De Silva AD, Dasanayake WMDK, Wickremasinghe GD, Karunatilake RMCH, De Silva R
Publication year: 2018

Fernando SJA, Faiz NM, Handunnetti SM, De Silva AD, Dasanayake WMDK, Wickremasinghe GD, Karunatilake RMCH, De Silva R. Preliminary study on Chronic granulomatous disease in Sri Lanka. Allergy Asthma & Clinical Immunology. 2018; 14: 37. doi:  10.1186/s13223-018-0264-7

Optimization of isolation of BK viral DNA from renal transplant patients and VP1 gene- based genotyping

Poster Presentations at National Conferences & Symposia
Ratnayake AKDVY, Fernando N, Gajanayake T, Handunnetti SM, Jayamaha CJS
Publication year: 2018

Ratnayake AKDVY, Fernando N, Gajanayake T, Handunnetti SM, Jayamaha CJS. Optimization of isolation of BK viral DNA from renal transplant patients and VP1 gene- based genotyping. Proceeding of the 10th Annual Scientific Sessions of IBMBB, University of Colombo. 21st November 2018, pp: 37

Is total serum nitrite and nitrate (NOx) level in dengue patients a potential prognostic marker of dengue haemorrhagic fever?

Publications in Peer-reviewed indexed Journals
Maheshi Sasika Mapalagamage, Shiroma Mangalika Handunnetti, Gayani Premawansa, Sharmila Thillainathan, Geekiyanage Tharanga Geethapriya Fernando, Karunayokiny Kanapathippillai, Rajitha Wickremeshinghe, Aruna Dharshan de Silva, Sunil Premawansa
Publication year: 2018

Maheshi Sasika Mapalagamage, Shiroma Mangalika Handunnetti, Gayani Premawansa, Sharmila Thillainathan, Geekiyanage Tharanga Geethapriya Fernando, Karunayokiny Kanapathippillai, Rajitha Wickremeshinghe, Aruna Dharshan de Silva, Sunil Premawansa. Is total serum nitrite and nitrate (NOx) level in dengue patients a potential prognostic marker of dengue haemorrhagic fever? Disease Markers, 2018; Article ID: 5328681, doi.org/10.1155/2018/5328681

Is Catalase KatE activity a survival mechanism of Leptospira interrogans?

Oral Presentations at National Conferences & Symposia
Barupala NP, Fernando N, Handunnetti SM and Premawansa S
Publication year: 2018

Barupala NP, Fernando N, Handunnetti SM and Premawansa S. Is Catalase KatE activity a survival mechanism of Leptospira interrogans? Proceeding of the 38th Annual Sessions of the IOB-SL, 2018; pp: 30

In vivo and in vitro studies on anti-inflammatory potential of Alpinia calcarata Rosc. Rhizome and leaf essential oils

Oral Presentations at International Conferences & Symposia
Chandrakanthan M, Kathigamanthar S, Maurya AK, Pal A, Handunnetti SM, Premakumara GAS
Publication year: 2018

Chandrakanthan M, Kathigamanthar S, Maurya AK, Pal A, Handunnetti SM, Premakumara GAS. In vivo and in vitro studies on anti-inflammatory potential of Alpinia calcarata Rosc. Rhizome and leaf essential oils. Asian Symposium on Medicinal Plants, Spices and Other Natural Products XVI, Colombo, Sri Lanka, 12-14th December 2018, pp 92

In vitro study on the effect of antimicrobial agents on inflammatory cytokine response in leptospirosis. (OP11)

Oral Presentations at National Conferences & Symposia
Sam G, Fernando N, Rajapakse S, Handunnetti SM
Publication year: 2018

Sam G, Fernando N, Rajapakse S, Handunnetti SM In vitro study on the effect of antimicrobial agents on inflammatory cytokine response in leptospirosis. (OP11). Proceeding of the 10th Annual Scientific Sessions of IBMBB, University of Colombo. 21st November 2018, pp: 25

In vitro pro-inflammatory enzyme inhibition and anti-oxidant potential of selected Sri Lankan medicinal plants

Publications in Peer-reviewed indexed Journals
Perera, HDSM, Samarasekara R, Handunnetti S, Weerasena OVDS, Weeratunga HD, Jabeen A, Chaudhary MI
Publication year: 2018

Perera, HDSM, Samarasekara R, Handunnetti S, Weerasena OVDS, Weeratunga HD, Jabeen A, Chaudhary MI. In vitro pro-inflammatory enzyme inhibition and anti-oxidant potential of selected Sri Lankan medicinal plants. BMC Complementary and Alternative Medicine. 2018; 18: 271

Immuno-proteomic characterization of Vespa affinis (Lesser Banded Hornet) venom and its cross-reactivity with the venom of Vespula vulgaris

Poster Presentations at National Conferences & Symposia
Gunasekara DLPE, Handunnetti SM, Premawansa S, Dasanayake WMDK, Karunatilake C, Ratnayake IP, Seneviratne SL, Dias RKS, Premakumara GAS, De Silva R
Publication year: 2018

Gunasekara DLPE, Handunnetti SM, Premawansa S, Dasanayake WMDK, Karunatilake C, Ratnayake IP, Seneviratne SL, Dias RKS, Premakumara GAS, De Silva R. Immuno-proteomic characterization of Vespa affinis (Lesser Banded Hornet) venom and its cross-reactivity with the venom of Vespula vulgaris. Proceeding of the 10th Annual Scientific Sessions of IBMBB, University of Colombo. 21st November 2018, pp: 33

IgM and IgG response against a specific protein antigen in rats orally fed with a herbal formulation. (OP10)

Oral Presentations at National Conferences & Symposia
Ranaweera BVLR, Abeysekera A, Weerasena OVDSJ, Handunnetti SM
Publication year: 2018

Ranaweera BVLR, Abeysekera A, Weerasena OVDSJ, Handunnetti SM. IgM and IgG response against a specific protein antigen in rats orally fed with a herbal formulation. (OP10). Proceeding of the 10th Annual Scientific Sessions of IBMBB, University of Colombo. 21st November 2018, pp: 24

High levels of Angiopoietin 2 and Angiopoietin 2/1 at critical stage of DHF patients and their association with clinical and biochemical parameters. (OP09)

Oral Presentations at National Conferences & Symposia
Mapalagamage MS, Handunnetti SM, Wickremasinghe R, Premawansa G, Thillainathan S, Fernando T, Khanapathypillai K, De Silva AD, Premawansa S
Publication year: 2018

Mapalagamage MS, Handunnetti SM, Wickremasinghe R, Premawansa G, Thillainathan S, Fernando T, Khanapathypillai K, De Silva AD, Premawansa S. High levels of Angiopoietin 2 and Angiopoietin 2/1 at critical stage of DHF patients and their association with clinical and biochemical parameters. (OP09). Proceeding of the 10th Annual Scientific Sessions of IBMBB, University of Colombo. 21st November 2018, pp: 23

Direct degranulation of rat mast cells (RBL-2H3) and increase in generation of superoxide anion (O2-) induced by aqueous extract of Acacia pollen and Apis dorsata venom. (OP06)

Oral Presentations at National Conferences & Symposia
Ishaka GKD, Gangani PD, Rukshala BAD, Gunasekara DLPE, Fernando N, Handunnetti SM
Publication year: 2018

Ishaka GKD, Gangani PD, Rukshala BAD, Gunasekara DLPE, Fernando N, Handunnetti SM. Direct degranulation of rat mast cells (RBL-2H3) and increase in generation of superoxide anion (O2-) induced by aqueous extract of Acacia pollen and Apis dorsata venom. (OP06). Proceeding of the 10th Annual Scientific Sessions of IBMBB, University of Colombo. 21st November 2018, pp: 20

Development of a colourimetric reverse transcription loop-mediated isothermal amplification assay for the rapid detection of different serotypes of the dengue virus

Oral Presentations at National Conferences & Symposia
Ariyaratne MHJD, Nguyen A, De Silva AD, Fernando N, Weerasena OVDSJ, Handunnetti SM
Publication year: 2018

Ariyaratne MHJD, Nguyen A, De Silva AD, Fernando N, Weerasena OVDSJ, Handunnetti SM. Development of a colourimetric reverse transcription loop-mediated isothermal amplification assay for the rapid detection of different serotypes of the dengue virus. (OP12). Proceeding of the 10th Annual Scientific Sessions of IBMBB, University of Colombo. 21st November 2018, pp: 26

Comparison of hyaluronidase from venom of Apis dorsata Fabricius and Vespa affinis Linnaeus. (OP08)

Oral Presentations at National Conferences & Symposia
Gunasekara DLPE, Handunnetti SM, Premawansa S, Dasanayake WMDK, Ratnayake IP, Seneviratne SL, Dias RKS, Premakumara GAS, De Silva R
Publication year: 2018

Gunasekara DLPE, Handunnetti SM, Premawansa S, Dasanayake WMDK, Ratnayake IP, Seneviratne SL, Dias RKS, Premakumara GAS, De Silva R. Comparison of hyaluronidase from venom of Apis dorsata Fabricius and Vespa affinis Linnaeus. (OP08). Proceeding of the 10th Annual Scientific Sessions of IBMBB, University of Colombo. 21st November 2018, pp: 22

Comparison of a two-step and a novel single step method for neutrophil isolation

Poster Presentations at National Conferences & Symposia
Lakmali AKD, Fernando N, Handunnetti SM, Premawansa S
Publication year: 2018

Lakmali AKD, Fernando N, Handunnetti SM, Premawansa S. Comparison of a two-step and a novel single step method for neutrophil isolation. Proceeding of the 10th Annual Scientific Sessions of IBMBB, University of Colombo. 21st November 2018, pp: 35

A preliminary study of early clinical and laboratory indicators of acute dengue illness

Oral Presentations at National Conferences & Symposia
Sigera PC, De Silva NL, Weeratunga P, Rajapadsha S, Jayasinghe KSA, Handunnetti S, Fernando D
Publication year: 2018

Sigera PC, De Silva NL, Weeratunga P, Rajapadsha S, Jayasinghe KSA, Handunnetti S, Fernando D. A preliminary study of early clinical and laboratory indicators of acute dengue illness. Proceeding of the 74th Annual Session of SLAAS, 2018; pp: 4

A bioactive resveratrol trimer from the stem bark of Sri Lankan endemic plant Vateria copallifera

Publications in Peer-reviewed indexed Journals
Samaradivakara SP, Samarasekera R, Handunnetti SM, Weerasena OVDSJ, Al-Hamashi AA, Slama JT, Taylor WR, Alhadidi Q, Shah ZA, Perera L, Tillekeratne LMV
Publication year: 2018

Samaradivakara SP, Samarasekera R, Handunnetti SM, Weerasena OVDSJ, Al-Hamashi AASlama JTTaylor WRAlhadidi QShah ZAPerera LTillekeratne LMV. A bioactive resveratrol trimer from the stem bark of Sri Lankan endemic plant Vateria copallifera. Journal of Natural Products. 2018 Jul 24. doi: 10.1021/acs.jnatprod.7b00892. [Epub ahead of print]

The in vitro effect of pathogenic Leptospira on FOXP3 expression in lymphocytes

Oral Presentations at National Conferences & Symposia
Dayarathna HMSP, Fernando N, Handunnetti SM, Weerasena OVDSJ
Publication year: 2017

Dayarathna HMSP, Fernando N, Handunnetti SM, Weerasena OVDSJ. The in vitro effect of pathogenic Leptospira on FOXP3 expression in lymphocytes. (OP06) Proceedings of the 9th Annual Scientific Sessions of IBMBB, University of Colombo. 07th July 2017, pp: 17

The effect of Munronia pinnata on natural killer cells

Poster Presentations at National Conferences & Symposia
Fernando NA, Handunnetti SM, Hapuaarachchi S
Publication year: 2017

Fernando NA, Handunnetti SM, Hapuaarachchi S. The effect of Munronia pinnata on natural killer cells. (PP05). Proceedings of the 9th Annual Scientific Sessions of the IBMBB, University of Colombo. 07th July 2017, pp: 33

Studies on in vitro anti-inflammatory activities of ethanol extract of bark of Calophyllum inophyllum L. (OP15)

Oral Presentations at National Conferences & Symposia
Perera HDSM, Samarasekaera R, Handunnetti S, Weerasena OVDSJ, Jabeen A,Choudhary MI
Publication year: 2017

Perera HDSM, Samarasekaera R, Handunnetti S, Weerasena OVDSJ, Jabeen A,Choudhary MI. Studies on in vitro anti-inflammatory activities of ethanol extract of bark of Calophyllum inophyllum L. (OP15). Proceedings of the 9th Annual Scientific Sessions of IBMBB, University of Colombo. 07th July 2017, pp: 26

Real-time qPCR as a reference standard test for diagnosis of leptospirosis

Oral Presentations at International Conferences & Symposia
Roshan Niloofa, Lilani Karunanayake, H Janaka de Silva, Senaka Rajapakse, Sunil Premawansa. Shiroma Handunnetti
Publication year: 2017

Roshan Niloofa, Lilani Karunanayake, H Janaka de Silva, Senaka Rajapakse, Sunil Premawansa. Shiroma Handunnetti. Real-time qPCR as a reference standard test for diagnosis of leptospirosis. 10th International Leptospirosis Society Scientific Meeting, Palmerston, New Zealand, 27th Nov-1stDec 2017, pp 120

Reactive nitrogen species (RNS) and reactive oxygen species (ROS) and their associations with dengue and leptospirosis infections

Books/Book Chapter
Publication year: 2017

Sunil Premawansa, Narmada Fernando, Maheshi Mapalagamage and Shiroma Handunnetti. Reactive nitrogen species (RNS) and reactive oxygen species (ROS) and their associations with dengue and leptospirosis infections. In Gloria Scientiam, The Golden Jubilee Commemorative Volume, Faculty of Science, University of Kelaniya, Sri Lanka, Ed: MJS Wijeratne & WL Chandrasekara. October 2017, Vidyalankara Printers, ISBN: 978-955-704-041-7

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