Narmada Fernando, Shalini Wickramasinghe, Roshan Niloofa, Chathuraka Rodrigo, Lilani Karunanayake, H Janaka de Silva, Rajitha Wickramasinghe, Sunil Premawansa, Senaka Rajapakse, Shiroma Handunnetti. Protein carbonyl as a biomarker of oxidative stress in severe leptospirosis, and its usefulness in differentiating leptospirosis from dengue infections. PLoS ONE. 2016; 11(6): e0156085. doi:10.1371/journal. pone.0156085

Kumari KDKP, Samarasinghe K, Handunnetti SM, Suresh TS. Preliminary Studies on Activity Guided Fractionation of the Ethanolic Extract of Dried Flowers of Aegle Marmelos. International Journal of Green and Herbal Chemistry. 2016; 5(2): 122-138

Vindhya A.K. Fernando, Jagath Weerasena , Inoka C. Perera , Chandima D. Dangalle , Shiroma Handunnetti, Sunil Premawansa Mayuri R. Wijesinghe. Lethal and sub-lethal effects on the Asian common toad Duttaphrynus melanostictus from hexavalent chromium. Aquatic Toxicology, 2016; 177:98-105. May 2016, DOI:10.1016/j

Sachindra M Perera, Radhika Samarasekera, Shiroma M Handunnetti, Jagathpriya Weerasena. In vitro anti-inflammatory and anti-oxidant activities of Sri Lankan medicinal plants. Industrial Crops and Products, 2016; 94:610-620

Saroopa P Samaradivakara, Radhika Samarasekera, Shiroma M Handunnetti, Jagathpriya Weerasena. Cholinesterase, protease inhibitory and antioxidant capacities of Sri Lankan medicinal plants. Industrial Crops & Products, 2016; 83:227-234

Senaka Rajapakse, Praveen Weeratunga, M.J. Roshan Niloofa, Narmada Fernando, Nipun Lakshitha Fernando, Chathuraka Rodrigo, SachithMaduranga, Nuwanthi nandasiri, Sunil Premawansa, H. Janaka De Silva, Lilani Karunanayake, Shiroma Handunnetti. A diagnostic scoring model for leptospirosis in resource limited settings – A prospective study. PLOS Neglected Tropical Diseases. 2016; 10 (6): e0004513. doi:10.1371/journal.pntd.0004513

Sathkumara H, De Silva AD, De Silva NR, Handunnetti S. Genetics of common variable immunodeficiency: role of transmembrane activator and calcium-modulator and cyclophilin ligand interactor. International Journal of Immunogenetics. 2015 (19 JUN), DOI: 10.1111/iji.12217

Eugene EJ, Handunnetti SM, Wickramasinghe SA, Kalugalage TL, Rodrigo C, Wickramasinghe H, Dikmadugoda N, Somaratne P, de Silva HJ and Rajapakse S. Evaluation of two immunodiagnostic tests for early rapid diagnosis of leptospirosis in Sri Lanka: a preliminary study. BMC Infectious Diseases. 2015; 15:319 DOI 10.1186/s12879-015-1080

Niloofa R, Fernando N, de Silva NL, Karunanayake L, Wickramasinghe H, Dikmadugoda N, Premawansa G, Wickramasinghe R, de Silva HJ, Premawansa S, Rajapakse S, Handunnetti S. (2015) Diagnosis of Leptospirosis: Comparison between Microscopic Agglutination Test, IgM-ELISA and IgM Rapid Immunochromatography Test. PLoS ONE. 2015 Jun 18; 10(6): e0129236. doi: 10.1371/ journal.pone.0129236

Rajapakse S, Rodrigo C, Handunnetti SM, Fernando SD. Current immunological and molecular tools for leptospirosis: diagnostics, vaccine design, and biomarkers for predicting severity. Annals of Clinical Microbiology and Antimicrobials. 2015 Jan 16; 14:2. doi: 10.1186/s12941-014-0060-2DOI 10.1186/s12941-014-0060-2

Senaka Rajapakse, Praveen Weeratunga, M.J. Roshan Niloofa, Narmada Fernando, Chathuraka Rodrigo, SachithMaduranga, NipunLakshitha Fernando, H. Janaka De Silva, Lilani Karunanayake, Shiroma Handunnetti. Clinical and laboratory associations of severity in a Sri Lankan cohort of patients with serologically confirmed leptospirosis – A prospective study. Transactions of Royal Society of Tropical Medicine Hygiene. 2015; 109 (11): 710-716

Ratnasooriya WD, Jayakody J, Handunnetti SM, Ratnasooriya C, Weerasekera KR. Anti-inflammatory activity of hot water infusion of Nyctanthus arbotristis flowers. Indian Journal of Pharmaceutical Science. 2015; 77:613-9

Wickremasinghe R, Kumara RR, De Silva DE, Ratnasooriya WD, Handunnetti SM.Inhibition of phagocytic and intracellular killing activity of human neutrophils by aqueous and methanolic leaf extracts of Ixora coccinea.Journal of Ethnopharmacology, 2014;153: 900–907

De Silva NL, Niloofa MJR, Fernando TRGN, Karunanayake L, Rodrigo C, de Silva HJ, Premawansa S, Handunnetti SM, Rajapaksa S. Changes in full blood count parameters leptospirosis: a prospective study. International Archives of Medicine, 2014, 7:31  doi: 10.1186/1755-7682-7-31

Kumari KDKP, Weerakoon TCS, Handunnetti SM, Samarasinghe K, Suresh TS. Anti-inflammatory activity of dried flower extracts of Aegle marmelos in Wistar rats. Journal of Ethnopharmacology, 2014:151:1202-1208

Kalugalage TL, Rodrigo C, Vithanage T, Somaratne P, De Silva HJ, Handunnetti SM, Rajapakse S.  Low serum total nitrite and nitrate levels in severe leptospirosis. BMC Infectious Diseases, 2013; 13-206

Perera MK, Herath NP, Pathirana SL, Phone-Kyaw M, Alles HK, Mendis KN, Premawansa S, Handunnetti SM. Association of high plasma TNF-α levels and TNF-α/ IL-10 ratios with TNF2 allele in severe P. falciparum malaria patients in Sri Lanka. Pathogens & Global Health, 2013; 107:21-29

Wijayalath W, Cheesman S, Tanabe K, Handunnetti S, Carter R, Pathiarana S. Strain-specific protective effect of the immunity induced by live malarial sporozoites under chloroquine cover. PLoS ONE, 2012; 7(9): e45861. doi:10.1371/journal.pone.0045861

Gunaratna RT, Handunnetti SM, Bulathsinghalage MRC, Somaratne P, Jayanaga A, De Silva HJ, Rajapakse S. Serum nitrite levels in Sri Lankan patients with Leptospirosis. Asian Pacific Journal of Tropical Medicine, 2012; 75-78

Sawai H, Otani H, Arisue N, Palacpac N, de O Martins L, Pathirana S, Handunnetti S, Kawai S, Kishino H, Horii T and Tanabe K.  Lineage-specific positive selection at the merozoite surface protein 1 (msp1) locus of Plasmodium vivax and related simian malaria parasites.BMC Evolutionary Biology, 2010; 10: 52

Wickramarachchi T, Premaratne PH, Dias S, Handunnetti SM and Udagama-Randeniya PV. Genetic complexity of Plasmodium vivax infections in Sri Lanka reflected at the Merozoite Surface Protein-3α locus Annals of Tropical Medicine and Parasitology, 2010; 104:95-108

Pathirana PPSL, Ekanayake K, Howard RJ, Mendis KN, and Handunnetti SM. Cytoadherence and its association with clinical disease in Plasmodium falciparum infections in Sri Lanka.The Journal of National Science Foundation, 2010; 38:233-240

Arawwawala M, Thabrew I, Arambawela L and Handunnetti SM.Anti-inflammatory activity of Trichosanthes cucumerina Linn.In rats.Journal of Ethnopharmacology, 2010; 131:538-543

Munasighe RA, Ileperuma M, Kapilananda GM, Premawansa G, Handunnetti SM and Premawansa S. Spleen modulation of cytoadherence properties of Plasmodium falciparum.Scandinavian Journal of Infectious Diseases, 2009; 41:538-539

Handunnetti SM, Kumara RR, Deraniyagala SA and Ratnasooriya WD. Anti-inflammatory activity of methanolic leaf extract of Ixora coccinea. Pharmacognosy Research, 2009; 1:80-90

Wijayalath W, Cheesman S,  Rajakaruna J, Handunnetti S, Carter R and Pathirana S. Evidence for strain-specific protective immunity against blood-stage parasites of Plasmodium cynomolgi in toque monkey.  Parasite Immunology, 2008; 30: 630-636

Tanabe K, Escalante A, Sakihama N, Honda M, Arisue N, Horii T, Culleton R, Hayakawa T, Hashimoto Tetsuo, Longacre S, Pathirana S, Handunnetti S, Kishino H. Recent independent evolution of msp1 polymorphism in Plasmodium vivax and related simian malaria parasites. Molecular Biochemical Parasitology, 2007; 156:74-79

Munasinghe-Gunasekera A, Wickramarachchi WTA, Ganguli I, Perera KLRL, Premaratne H,  Handunnetti SM, Udagama-Randeniya PV and Wirth DF. Genetic diversity and selection at the Plasmodium vivax apical membrane antigen-1 (PvAMA-1) locus in a Sri Lankan population. Molecular Biology & Evolution, 2007; 24:939-942

Wickramarachchi WTA, Illeperuma RJ, Perera KLRL, Bandara S, Longacre S, Handunnetti SM and  Udagama-Randeniya PV. Comparison of naturally acquired antibody responses against the C-terminal products of Plasmodium vivax merozoite surface protein-1 under low transmission and unstable malaria conditions in Sri Lanka. International Journal of Parasitology, 2007; 37: 199-208

Wickramarachchi T, Premaratne PH, Perera KLRL, Bandara S, Kocken CHM,  Thomas AW, HandunnettiSM and Udagama-Randeniya PV. Natural human antibody responses to Plasmodium vivax apical membrane antigen 1 under low transmission and unstable malaria conditions in Sri Lanka. Infection & Immunity, 2006; 74:798-801