Professor Shiroma M Handunnetti
Institute of Biochemistry, Molecular Biology and Biotechnology (IBMBB)
Publications
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Comparison of hyaluronidase from venom of Apis dorsata Fabricius and Vespa affinis Linnaeus. (OP08)
Gunasekara DLPE, Handunnetti SM, Premawansa S, Dasanayake WMDK, Ratnayake IP, Seneviratne SL, Dias RKS, Premakumara GAS, De Silva R. Comparison of hyaluronidase from venom of Apis dorsata Fabricius and Vespa affinis Linnaeus. (OP08). Proceeding of the 10th Annual Scientific Sessions of IBMBB, University of Colombo. 21st November 2018, pp: 22
Comparison of antioxidant properties of Cyathula prostrata Linn and Achyranthes aspera Linn grown in Sri Lanka
Dissanayake DPA, Sivaganesh S, Tissera MHA, Handunnetti SM, Arawwawala LDAM. Comparison of antioxidant properties of Cyathula prostrata Linn and Achyranthes aspera Linn grown in Sri Lanka, Research and Review Insights, 2018; 2(3):1-3; ISSN: 2515-2637; doi: 10.15761/RRI.1000138.
Comparison of a two-step and a novel single step method for neutrophil isolation
Lakmali AKD, Fernando N, Handunnetti SM, Premawansa S. Comparison of a two-step and a novel single step method for neutrophil isolation. Proceeding of the 10th Annual Scientific Sessions of IBMBB, University of Colombo. 21st November 2018, pp: 35
A preliminary study of early clinical and laboratory indicators of acute dengue illness
Sigera PC, De Silva NL, Weeratunga P, Rajapadsha S, Jayasinghe KSA, Handunnetti S, Fernando D. A preliminary study of early clinical and laboratory indicators of acute dengue illness. Proceeding of the 74th Annual Session of SLAAS, 2018; pp: 4
A bioactive resveratrol trimer from the stem bark of Sri Lankan endemic plant Vateria copallifera
Samaradivakara SP, Samarasekera R, Handunnetti SM, Weerasena OVDSJ, Al-Hamashi AA, Slama JT, Taylor WR, Alhadidi Q, Shah ZA, Perera L, Tillekeratne LMV. A bioactive resveratrol trimer from the stem bark of Sri Lankan endemic plant Vateria copallifera. Journal of Natural Products. 2018 Jul 24. doi: 10.1021/acs.jnatprod.7b00892. [Epub ahead of print]
The in vitro effect of pathogenic Leptospira on FOXP3 expression in lymphocytes
Dayarathna HMSP, Fernando N, Handunnetti SM, Weerasena OVDSJ. The in vitro effect of pathogenic Leptospira on FOXP3 expression in lymphocytes. (OP06) Proceedings of the 9th Annual Scientific Sessions of IBMBB, University of Colombo. 07th July 2017, pp: 17
The effect of Munronia pinnata on natural killer cells
Fernando NA, Handunnetti SM, Hapuaarachchi S. The effect of Munronia pinnata on natural killer cells. (PP05). Proceedings of the 9th Annual Scientific Sessions of the IBMBB, University of Colombo. 07th July 2017, pp: 33
Studies on in vitro anti-inflammatory activities of ethanol extract of bark of Calophyllum inophyllum L. (OP15)
Perera HDSM, Samarasekaera R, Handunnetti S, Weerasena OVDSJ, Jabeen A,Choudhary MI. Studies on in vitro anti-inflammatory activities of ethanol extract of bark of Calophyllum inophyllum L. (OP15). Proceedings of the 9th Annual Scientific Sessions of IBMBB, University of Colombo. 07th July 2017, pp: 26
Real-time qPCR as a reference standard test for diagnosis of leptospirosis
Roshan Niloofa, Lilani Karunanayake, H Janaka de Silva, Senaka Rajapakse, Sunil Premawansa. Shiroma Handunnetti. Real-time qPCR as a reference standard test for diagnosis of leptospirosis. 10th International Leptospirosis Society Scientific Meeting, Palmerston, New Zealand, 27th Nov-1stDec 2017, pp 120
Reactive nitrogen species (RNS) and reactive oxygen species (ROS) and their associations with dengue and leptospirosis infections
Sunil Premawansa, Narmada Fernando, Maheshi Mapalagamage and Shiroma Handunnetti. Reactive nitrogen species (RNS) and reactive oxygen species (ROS) and their associations with dengue and leptospirosis infections. In Gloria Scientiam, The Golden Jubilee Commemorative Volume, Faculty of Science, University of Kelaniya, Sri Lanka, Ed: MJS Wijeratne & WL Chandrasekara. October 2017, Vidyalankara Printers, ISBN: 978-955-704-041-7
Preliminary Study on X-linked chronic granulomatous disease in Sri Lanka. (OP04)
Fernando SJA, De Silva NR, De Silva AD, Handunnetti SM, Dassanayake D. Preliminary Study on X-linked chronic granulomatous disease in Sri Lanka. (OP04) Proceedings of the 9th Annual Scientific Sessions of IBMBB, University of Colombo. 07th July 2017, pp: 15
Preliminary study on identification of autosomal recessive p47phox mutations in patients with chronic granulomatous disease in Sri Lanka. (OP05)
Mifra FN, de Silva AD, de Silva NR, Handunnetti SM, Dassanayake D. Preliminary study on identification of autosomal recessive p47phox mutations in patients with chronic granulomatous disease in Sri Lanka. (OP05). Proceedings of the 9th Annual Scientific Sessions of IBMBB, University of Colombo. 07th July 2017, pp: 16
Preliminary study on allergenic pollen records from airborne samples in selected locations of urban and semi-urban areas in Western Province of Sri Lanka
Ishaka GKD, Premawansa S, Prematilake TR, De Silva R, Handunnetti SM, Fernando A, Premawansa G. Preliminary study on allergenic pollen records from airborne samples in selected locations of urban and semi-urban areas in Western Province of Sri Lanka. (OP07). Proceedings of the 9th Annual Scientific Sessions of IBMBB, University of Colombo. 07th July 2017, pp: 18
Phytochemical profile and in vitro anti-inflammatory activity of aqueous leaf extract of Sri Lankan variety of Psidium guajava L. (OP17)
Kariawasam KWJC, Pathirana RN, Ratnasooriya W, Handunnetti SM, Abeysekera WPKM. Phytochemical profile and in vitro anti-inflammatory activity of aqueous leaf extract of Sri Lankan variety of Psidium guajava L. (OP17). Proceedings of the 9th Annual Scientific Sessions of IBMBB, University of Colombo. 07th July 2017, pp: 28
Phytochemical profile and in vitro anti-inflammatory activity of aqueous leaf extract of Sri Lankan variety of Psidium guajava L
Kariyawasam. K. W. J. C., Pathirana. R. N., Ratnasooriya W. D., S. Handunnetti and Abeysekera W. P. K. M. Phytochemical profile and in vitro anti-inflammatory activity of aqueous leaf extract of Sri Lankan variety of Psidium guajava L. Journal of Pharmacognosy and Phytochemistry, 2017; 6(4). 22-26
Optimization of the day of sampling for expression of T cell dependent B cell activation
Ranaweera BVLR, Edward D, Abeysekara AM , Weerasena OVDSJ, Handunnetti SM. Optimization of the day of sampling for expression of T cell dependent B cell activation. (OP10). Proceedings of the 9th Annual Scientific Sessions of Institute of Biochemistry, Molecular Biology & Biotechnology (IBMBB), University of Colombo. 07th July 2017, pp: 21
Multilocus Sequence Typing of Leptospira from clinical isolates in Sri Lanka
Karunanayake Lilani, Vimal Raj R, Anwesh M, Muruganandam N, Perera R, Niloofa R, Fernando N, Handunnetti S. Premawansa S, Rajapakse S., Vijayachari P. Multilocus Sequence Typing of Leptospira from clinical isolates in Sri Lanka. 10th International Leptospirosis Society Scientific Meeting, Palmerston, New Zealand, 27th Nov-1stDec 2017; pp 55
Low total serum nitrite and nitrate levels on admission in dengue patients as prognostic markers for developing dengue hemorrhagic fever.
Mapalagamage M, Handunnetti SM, Premawansa G, Thillainathan S, Fernando T, Kanapathippillai K, De Silva AD, Premawansa S. Low total serum nitrite and nitrate levels on admission in dengue patients as prognostic markers for developing dengue hemorrhagic fever. (OP11). Proceedings of the 9th Annual Scientific Sessions of IBMBB, University of Colombo. 07th July 2017, pp: 22
Inhibition of nitric oxide production in mouse macrophages (RAW264.7) by Artocarpus nobilis Thw. (OP12)
Rukshala BAD, Handunnetti SM, de Silva ED. Inhibition of nitric oxide production in mouse macrophages (RAW264.7) by Artocarpus nobilis Thw. (OP12). Proceedings of the 9th Annual Scientific Sessions of IBMBB, University of Colombo. 07th July 2017, pp: 23.
In vitro Butyrylcholinesterase and protease inhibitory activities of selected medicinal plant extracts.
Samaradivakara SP, Samarasekara R, Handunnetti SM, Weerasena OVDSJ. In vitro Butyrylcholinesterase and protease inhibitory activities of selected medicinal plant extracts. (PP06). Proceedings of the 9th Annual Scientific Sessions of the IBMBB, University of Colombo. 07th July 2017, pp: 34
IgE cross-reactivity of phospholipase A2 and hyaluronidase of Apis dorsata (Giant Asian honeybee) and Apis mellifera (Western honeybee) venom: Possible use of A. mellifera venom for diagnosis and immunotherapy of patients allergic to A. dorsata venom
Peshala Gunasekara, Shiroma Handunnetti, Sunil Premawansa, Elapatha Witharana, Dhanushka Dasanayake, Padmini Ratnayake, Suranjith Seneviratne, Sriyani Dias, Sirimal Premakumara, Rajiva de Silva. IgE cross-reactivity of phospholipase A2 and hyaluronidase of Apis dorsata (Giant Asian honeybee) and Apis mellifera (Western honeybee) venom: Possible use of A. mellifera venom for diagnosis and immunotherapy of patients allergic to A. dorsata venom. TOXICON, 2017; 137:27-35
Identification of allergenic venom components of Apis dorsata Fabricius and comparison of those with Apis mellifera Linnaeus
Gunasekara DLPE, Handunnetti S, Premawansa S, Witharana EWRA, Dassanayake WMDK, Rathnayake IP, Senevirathne SL, Dias RKS, Premakumara GAS de Silva R. Identification of allergenic venom components of Apis dorsata Fabricius and comparison of those with Apis mellifera Linnaeus. (OP09). Proceedings of the 9th Annual Scientific Sessions of IBMBB, University of Colombo. 07th July 2017, pp: 20
Establishment of methods for retrieving Leptospira organisms/ antigens in urine and blood
Weerasinghe HS, Fernando N, Rajapakse S, Premawansa S, Handunnetti SM. Establishment of methods for retrieving Leptospira organisms/ antigens in urine and blood. (PP03). Proceedings of the 9th Annual Scientific Sessions of the IBMBB, University of Colombo. 07th July 2017, pp: 31
Do human serum factors protect endothelial cells against pathogenic Leptospira?
Narmada Fernando, Shiroma Handunnetti, Lilani Karunanayake, Sunil Premawansa, Senaka Rajapakse. Do human serum factors protect endothelial cells against pathogenic Leptospira? 10th International Leptospirosis Society Scientific Meeting, Palmerston, New Zealand, 27th Nov-1stDec 2017; pp 245
Diagnosing a disease of farmers - Leptospirosis
Niloofa R, Premawansa S, Rajapakse S, Handunnetti SM. Diagnosing a disease of farmers – Leptospirosis. (OP08). Proceedings of the 9th Annual Scientific Sessions of IBMBB, University of Colombo. 07th July 2017, pp: 19
Determining performance characteristics of an immunochromatographic in vitro diagnostic test for diagnosis of Plasmodium falciparum malaria
Gunasekara WMKT de AW, Handunnetti SM, Premawansa S, Weerasena OVDSJ. Determining performance characteristics of an immunochromatographic in vitro diagnostic test for diagnosis of Plasmodium falciparum malaria. (PP04). Proceedings of the 9th Annual Scientific Sessions of the IBMBB, University of Colombo. 07th July 2017, pp: 32
Bioactivities of n-hexane fraction of Vateria copallifera and GC–MS anlysis of its phytoconstituents
Saroopa P Samaradivakara, Radhika Samarasekera, Viranga Tilekeratne, Shiroma M Handunnetti, Jagathpriya Weerasena, William R Taylor, Qasim Alhadidi, Zahoor A Shah. Bioactivities of n-hexane fraction of Vateria copallifera and GC–MS anlysis of its phytoconstituents. Industrial Crops and Products, 2017; 97:87-92
Assessment of RNS and ROS production by healthy phagocytic cells stimulated with leptospires in vitro
Wickramasinghe Arachchi SM, Edward D, Fernando N, Handunnetti SM, Rajapakse S. Assessment of RNS and ROS production by healthy phagocytic cells stimulated with leptospires in vitro. (PP02). Proceedings of the 9th Annual Scientific Sessions of the IBMBB, University of Colombo. 07th July 2017, pp: 30
Applicability of malaria Rapid Diagnostic Tests in diagnosing non-falciparum malaria infections in Sri Lanka under zero-indigenous malaria setting
WM Kumudu TdeAW Gunasekera, Risintha G Premaratne, OVDS Jagathpriya Weerasena, Shiroma M Handunnetti, Sunil Premawansa, S Deepika Fernando. Applicability of malaria Rapid Diagnostic Tests in diagnosing non-falciparum malaria infections in Sri Lanka under zero-indigenous malaria setting. 73rd Annual Scientific Sessions of SLAAS. 2017
Antibiotic Susceptibility of Clinical Isolates of Human Leptospirosis in Sri Lanka
Karunanayake Lilani, Rajapaksha RRN, Perera KCR, Fernando N, Niloofa R, Handunnetti S, Premawansa S, Rajapakse S. Antibiotic Susceptibility of Clinical Isolates of Human Leptospirosis in Sri Lanka. 10th International Leptospirosis Society Scientific Meeting, Palmerstone, New Zealand, 27th Nov-1stDec 2017