Asexual blood stage malaria vaccines: can they protect malaria-exposed individuals against disease

Oral Presentations at National Conferences & Symposia
Amaratunga C, Perera KLRL, Gunawardene B, Jayasinghe A, Rajakaruna J, Holm I, Longacre S, Mendis K, and Handunnetti SM
Publication year: 2002

Amaratunga C, Perera KLRL, Gunawardene B, Jayasinghe A, Rajakaruna J, Holm I, Longacre S, Mendis K, and Handunnetti SM. Asexual blood stage malaria vaccines: can they protect malaria-exposed individuals against disease. Proceedings of the Scientific Sessions, Faculty of Medicine, University of Colombo, Sri Lanka, 5-7th  April, 2002; pp 28-29

Antibody responses of naturally infected individuals to asexual erythrocytic stage vaccine candidates of P. vivax in Sri Lanka

Oral Presentations at International Conferences & Symposia
Wickramarachchi, Perera KLRL, Bandara S, Longacre S, Thamas A, Handunnetti SM and Udagama-Randeniya PV
Publication year: 2002

Wickramarachchi, Perera KLRL, Bandara S, Longacre S, Thamas A, Handunnetti SM and Udagama-Randeniya PV. Antibody responses of naturally infected individuals to asexual erythrocytic stage vaccine candidates of P. vivax in Sri Lanka. Vivax Malaria Research: 2002 And Beyond, 2nd-3rd February, 2002; Bangkok, Thailand, pp 27

Studies on entomological parameters in a typical malaria endemic area in Sri Lanka

Oral Presentations at National Conferences & Symposia
Kaluarachchi S, Perera L, Gunawardana DM, and Handunnetti SM
Publication year: 2001

Kaluarachchi S, Perera L, Gunawardana DM, and Handunnetti SM. Studies on entomological parameters in a typical malaria endemic area in Sri Lanka. Proceedings of the 57thAnnual Sessions of the SLAAS, 2001; pp 25

Protection against disease in experimental immunization with a candidate malaria vaccine

Oral Presentations at National Conferences & Symposia
Amaratunga C, Perera L, Gunawardana B, Jayasinghe A, Rajakaruna J, Holm I, Longacre S, Mendis K, and Handunnetti SM
Publication year: 2001

Amaratunga C, Perera L, Gunawardana B, Jayasinghe A, Rajakaruna J, Holm I, Longacre S, Mendis K, and Handunnetti SM. Protection against disease in experimental immunization with a candidate malaria vaccine. Proceedings of the 57thAnnual Sessions of the SLAAS, 2001; pp 16

Pattern of IgG1 and IgG3 isotype responses to C-terminal processing products of Plasmodium vivax merozoite surface protein-1 in endemic populations of Sri Lanka

Oral Presentations at National Conferences & Symposia
Wickramarachchi WTA, Illeperuma RJ, Perera KLRL, Bandara S, Lokupitiya RS, Longacre S, Handunnetti SM, and Udagama-Randeniya PV
Publication year: 2001

Wickramarachchi WTA, Illeperuma RJ, Perera KLRL, Bandara S, Lokupitiya RS, Longacre S, Handunnetti SM, and Udagama-Randeniya PV. Pattern of IgG1 and IgG3 isotype responses to C-terminal processing products of Plasmodium vivax merozoite surface protein-1 in endemic populations of Sri Lanka. Proceedings of the 57thAnnual Sessions of the SLAAS, 2001; pp 20

Immunogenicity of merozoite surface protein-1 based malaria vaccine candidate antigen in combination with two novel adjuvants, MF59 and Montanide ISA 51

Oral Presentations at National Conferences & Symposia
Weerasinghe S, Amaratunga C, Perera K, Gamage K, Gunawardene B, Rajakaruna J, Holm I, Longacre S, and Handunnetti SM
Publication year: 2001

Weerasinghe S, Amaratunga C, Perera K, Gamage K, Gunawardene B, Rajakaruna J, Holm I, Longacre S, and Handunnetti SM. Immunogenicity of merozoite surface protein-1 based malaria vaccine candidate antigen in combination with two novel adjuvants, MF59 and Montanide ISA 51. Proceedings of the 57thAnnual Sessions of the SLAAS, 2001; pp 24

Autoagglutination abilities of Plasmodium falciparum parasite isolates from severe complicated and uncomplicated P. falciparum infections

Oral Presentations at National Conferences & Symposia
Munasinghe RA, Pathirana PPSL, Jagadeesh SAA, Ileperuma M, Handunnetti SM, and Premawansa S
Publication year: 2001

Munasinghe RA, Pathirana PPSL, Jagadeesh SAA, Ileperuma M, Handunnetti SM, and Premawansa S.  Autoagglutination abilities of Plasmodium falciparum parasite isolates from severe complicated and uncomplicated P. falciparum infections. Proceedings of the 57thAnnual Sessions of the SLAAS, 2001; pp 18

Associations between TNF-α IL-10 and IL-6 plasma cytokine levels and TNFαpolymorphisms inPlasmodium falciparum malaria with respect to disease severity

Oral Presentations at National Conferences & Symposia
Herath NP, Kapilananda GMG, Carter R, Perera MK, Handunnetti SM, and Premawansa S
Publication year: 2001

Herath NP, Kapilananda GMG, Carter R, Perera MK, Handunnetti SM, and Premawansa S. (2001). Associations between TNF-α IL-10 and IL-6 plasma cytokine levels and TNFαpolymorphisms inPlasmodium falciparum malaria with respect to disease severity. Proceedings of the 57thAnnual Sessions of the SLAAS, 2001; pp 17

Association between resetting of Plasmodium falciparum parasite isolates and hematological parameters of P. falciparum infected patients

Oral Presentations at National Conferences & Symposia
Munasinghe RA, Ileperuma M, Jagadeesh SAA, Premawansa G, Handunnetti SM, and Premawansa S.
Publication year: 2001

Munasinghe RA, Ileperuma M, Jagadeesh SAA, Premawansa G, Handunnetti SM, and Premawansa S.  Association between resetting of Plasmodium falciparum parasite isolates and hematological parameters of P. falciparum infected patients. Proceedings of the 57thAnnual Sessions of the SLAAS, 2001; pp 19

Antibody responses to a leading vaccine candidate PV66/AMA-1 induced by natural infections of Plasmodium vivax in humans

Oral Presentations at National Conferences & Symposia
Wickramarachchi, WTA, Perera, KLRL, Bandara, S, Thomas, A, Handunetti, SM and Udagama-Randeniya, PV
Publication year: 2001

Wickramarachchi, WTA, Perera, KLRL, Bandara, S, Thomas, A, Handunetti, SM and Udagama-Randeniya, PV. Antibody responses to a leading vaccine candidate PV66/AMA-1 induced by natural infections of Plasmodium vivax in humans. Proceedings of the 21stAnnual Sessions of the IOB-SL, 2001; pp 26

Variation of infectivity of Plasmodium cynomolgi ceylonensis during the course of blood infections in its host Macaca sinica

Oral Presentations at National Conferences & Symposia
Amaratunga C, Rajakaruna J, Gunawardene B, Pannila S, Jayasinghe A, and   Handunnetti SM
Publication year: 2000

Amaratunga C, Rajakaruna J, Gunawardene B, Pannila S, Jayasinghe A, and   Handunnetti SM.  Variation of infectivity of Plasmodium cynomolgi ceylonensis during the course of blood infections in its host Macaca sinica. Proceedings of the 20thAnnual Sessions of the Institute of Biology, Sri Lanka (IOB-SL), 2000; pp 36

Susceptibility of P. vivax infections to chloroquine

Oral Presentations at National Conferences & Symposia
Kapilananda GMG, Jayasinghe JKA, Gunawardana MBP, Ekanayaka K, Wickramaarachchi WTA, and Handunnetti SM
Publication year: 2000

Kapilananda GMG, Jayasinghe JKA, Gunawardana MBP, Ekanayaka K, Wickramaarachchi WTA, and Handunnetti SM. Susceptibility of P. vivax infections to chloroquine. Proceedings of the 56thAnnual Sessions of the SLAAS, 2000; pp13

Sporozoite induced Plasmodium cynomolgi ceylonensis malarial infections in toque monkeys;a natural challenge system for evaluation of vaccine efficacy

Oral Presentations at National Conferences & Symposia
Amarathunga C, Pannila S, Rajakaruna J ,Jayasinghe A, Weerasinghe S, Perera KLRL,*Mendis K, and Handunnetti S M
Publication year: 2000

Amarathunga C, Pannila S, Rajakaruna J ,Jayasinghe A, Weerasinghe S, Perera KLRL,*Mendis K, and Handunnetti S M. Sporozoite induced Plasmodium cynomolgi ceylonensis malarial infections in toque monkeys;a natural challenge system for evaluation of vaccine efficacy. Proceedings of the 56thAnnual Sessions of the SLAAS, 2000; pp 17.

Seroepidemiology of potential vaccine candidate p42 representing a c-terminal fragment of Plasmodium vivax merozoite surface protein-1

Oral Presentations at National Conferences & Symposia
Wickramarachchi WTA, Perera KLRL, Bandara S, Longacre S, Handunnetti SM, and Udagama-Randeniya PV
Publication year: 2000

Wickramarachchi WTA, Perera KLRL, Bandara S, Longacre S, Handunnetti SM, and Udagama-Randeniya PV. Seroepidemiology of potential vaccine candidate p42 representing a c-terminal fragment of Plasmodium vivax merozoite surface protein-1.Proceedings of 1st Annual Academic Sessions of the Faculty of Science, University of Colombo, Sri Lanka, 2000; pp 35

Protection in toque monkeys immunized with merozoite surface protein-1 p19 in alum

Poster Presentations at International Conferences & Symposia
Amaratunga C, Nandasiri K, Weerasinghe S, Manamperi A, Holm I, Longacre S, and Handunnetti SM
Publication year: 2000

Amaratunga C, Nandasiri K, Weerasinghe S, Manamperi A, Holm I, Longacre S, and Handunnetti SM. Protection in toque monkeys immunized with merozoite surface protein-1 p19 in alum. New Challenges in Tropical Medicine and Parasitology, Oxford, 2000; pp 128

Protection against malaria in toque monkeys immunized with cynomolgi MSP1inv in alum

Oral Presentations at National Conferences & Symposia
Amarathunga C, Nandasiri K, Weerasinghe S, *Mananperi A, Holm I, Longacre S, and Handunnetti S M
Publication year: 2000

Amarathunga C, Nandasiri K, Weerasinghe S, *Mananperi A, Holm I, Longacre S, and Handunnetti S M. Protection against malaria in toque monkeys immunized with cynomolgi MSP1inv in alum. Proceedings of the 56thAnnual Sessions of the SLAAS, 2000; pp 16.

Immunoepidemiology of p19: a potential vaccine candidate based on Plasmodium vivax MSP-1

Oral Presentations at National Conferences & Symposia
Wickramarachchi WTA, Perera KLRL, Bandara S, Longacre S, Handunnetti SM, and Udagama-Randeniya PV
Publication year: 2000

Wickramarachchi WTA, Perera KLRL, Bandara S, Longacre S, Handunnetti SM, and Udagama-Randeniya PV. Immunoepidemiology of p19: a potential vaccine candidate based on Plasmodium vivax MSP-1. Proceedings of the 20thAnnual Sessions of the IOB-SL, 2000; pp37

Hypervariability in a leading vivax malaria vaccine candidate, C-terminal merozoite surface protein 1

Oral Presentations at National Conferences & Symposia
Mananperi A, Holm I, Perera L, Handunnetti SM, and Longacre S
Publication year: 2000

Mananperi A, Holm I, Perera L, Handunnetti SM, and Longacre S. Hypervariability in a leading vivax malaria vaccine candidate, C-terminal merozoite surface protein 1. Proceedings of the 56thAnnual Sessions of the SLAAS, 2000; pp 15.

Associations between TNF 1.2 and TNF 2.2 genotypes and plasma TNF levels in Plasmodium falciparum infected patients in relation to severity of disease

Oral Presentations at National Conferences & Symposia
Herath NP, Perera MK, Kapilananda GMG, Handunnetti SM, and Premawansa S
Publication year: 2000

Herath NP, Perera MK, Kapilananda GMG, Handunnetti SM, and Premawansa S. Associations between TNF 1.2 and TNF 2.2 genotypes and plasma TNF levels in Plasmodium falciparum infected patients in relation to severity of disease. Proceedings of the 56thAnnual Sessions of the SLAAS, 2000; pp 40

Allelic variation in a leading Plasmodium vivax malaria vaccine candidate, merozoite surface protein 1

Poster Presentations at International Conferences & Symposia
Manamperi A, Holm I, Perera L, Handunnetti SM, and Longacre S
Publication year: 2000

Manamperi A, Holm I, Perera L, Handunnetti SM, and Longacre S. Allelic variation in a leading Plasmodium vivax malaria vaccine candidate, merozoite surface protein 1. New Challenges in Tropical Medicine and Parasitology, Oxford, 2000; pp 71

Agglutinating phenotypes of parasite isolates from severe complicated and uncomplicated Plasmodium falciparum infections

Oral Presentations at National Conferences & Symposia
Munasinghe RA, Illeperuma M, Handunnetti SM, Premawansa S
Publication year: 2000

Munasinghe RA, Illeperuma M, Handunnetti SM, Premawansa S. Agglutinating phenotypes of parasite isolates from severe complicated and uncomplicated Plasmodium falciparum infections. Proceedings of the 56thAnnual Sessions of the SLAAS, 2000; pp 22

A ray of Hope for an effective vaccine against malaria

Oral Presentations at International Conferences & Symposia
Longacre S, Holm I, Nato F, Peters S, Chitarra V, Bently G, Manane A, Perera L, Amaratunge C,  Manamperi A, Weerasinghe S, and Handunnetti S
Publication year: 2000

Longacre S, Holm I, Nato F, Peters S, Chitarra V, Bently G, Manane A, Perera L, Amaratunge C,  Manamperi A, Weerasinghe S, and Handunnetti S.  A ray of Hope for an effective vaccine against malaria, Proceedings of “1st Health Opinion Leadership Conference in Latin America” 21st-23rd March, 2000; Rio de Janeiro, Brazil

Protection against heterologous Plasmodium cynomolgi infection in MSP1inv immunized toque monkeys.

Oral Presentations at National Conferences & Symposia
Amaratunga C, Weerasinghe S, Perera KLRL, Mendis K, Longacre S, and Handunnetti SM
Publication year: 1999

Amaratunga C, Weerasinghe S, Perera KLRL, Mendis K, Longacre S, and Handunnetti SM. Protection against heterologous Plasmodium cynomolgi infection in MSP1inv immunized toque monkeys. Proceedings of the 55thAnnual Sessions of the SLAAS, 1999; pp 20

A double antibody sandwich ELISA for the diagnosis of vivax malaria: a tool for further research

Publications in Peer-reviewed indexed Journals
Senevirathne N, Manamperi A, Kapilananda GMG, Longacre S, Handunnetti SM and Randeniya PV
Publication year: 1999

Senevirathne N, Manamperi A, Kapilananda GMG, Longacre S, Handunnetti SM and Randeniya PV. A double antibody sandwich ELISA for the diagnosis of vivax malaria: a tool for further research. Ceylon Journal of Medical Sciences, 1999; 43:11-18

Plasma cytokine levels in severe complicated Plasmodium falciparum

Oral Presentations at National Conferences & Symposia
Perera MK, Abeynayake SD, Phone-Kyaw M, Bandara S, Alles H, Fernando N, Wimalasena C, Pathirana SLP, Premawansa S, Mendis KN and Handunnetti SM
Publication year: 1998

Perera MK, Abeynayake SD, Phone-Kyaw M, Bandara S, Alles H, Fernando N, Wimalasena C, Pathirana SLP, Premawansa S, Mendis KN and Handunnetti SM. Plasma cytokine levels in severe complicated Plasmodium falciparum Proceedings of the 54thAnnual Sessions of the SLAAS, 1998; pp 32.

Cellular and humoral immune responses in Plasmodium cynomolgi MSP-1 p19 protected toque monkeys.

Oral Presentations at National Conferences & Symposia
Perera KLRL, Amaratunga C, Longacre S, Mendis KN and Handunnetti SM
Publication year: 1998

Perera KLRL, Amaratunga C, Longacre S, Mendis KN and Handunnetti SM Cellular and humoral immune responses in Plasmodium cynomolgi MSP-1 p19 protected toque monkeys. Proceedings of the 54thAnnual Sessions of the SLAAS, 1998; pp 2.

Baculovirus merozoite surface protein 1 C-terminal recombinant antigens are highly protective in a natural primate model for human Plasmodium vivax malaria

Publications in Peer-reviewed indexed Journals
Perera KLRL, Handunnetti SM, Holm I, Longacre S and Mendis KN
Publication year: 1998

Perera KLRL, Handunnetti SM, Holm I, Longacre S and Mendis KN. Baculovirus merozoite surface protein 1 C-terminal recombinant antigens are highly protective in a natural primate model for human Plasmodium vivax malaria. Infection & Immunity, 1998; 66:1500-1506

The Macaque models of human malarias: Their use for evaluation of vaccines

Oral Presentations at International Conferences & Symposia
Mendis KN, Perera KLRL, Handunnetti SM, and Longacre S
Publication year: 1997

Mendis KN, Perera KLRL, Handunnetti SM, and Longacre S. The Macaque models of human malarias: Their use for evaluation of vaccines. Second Global Meet on Parasitic Diseases, 18th -22nd August, 1997; Hyderabad, India, pp 42-43

Association between ABO blood groups and protection against severe and complicated Plasmodium falciparum

Oral Presentations at International Conferences & Symposia
Pathirana PPSL, Alles HK, Perera MK, Mendis KN and Handunnetti SM
Publication year: 1997

Pathirana PPSL, Alles HK, Perera MK, Mendis KN and Handunnetti SM. Association between ABO blood groups and protection against severe and complicated Plasmodium falciparum Second Global Meet on Parasitic Diseases, 18th -22nd August, 1997; Hyderabad, India, pp187-188

Association between ABO Blood groups and disease severity in Plasmodium falciparum malaria

Oral Presentations at National Conferences & Symposia
Pathirana PPSL, Alles HK, Perera MK, Phone-Kyaw M, Ekanayake K, Bandara S, Wijesinghe U, Somathilaka D, Wimalasena C, Abeynayake S,  Mendis KN, Handunnetti SM
Publication year: 1997

Pathirana PPSL, Alles HK, Perera MK, Phone-Kyaw M, Ekanayake K, Bandara S, Wijesinghe U, Somathilaka D, Wimalasena C, Abeynayake S,  Mendis KN, Handunnetti SM, Association between ABO Blood groups  and disease severity in Plasmodium falciparum Proceedings of the 53rd Annual Sessions of the SLAAS, 1997; pp 6.