Professor Shiroma M Handunnetti
Institute of Biochemistry, Molecular Biology and Biotechnology (IBMBB)
Publications
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A study of the involvement of Reactive Nitrogen Species (RNS) and Reactive Oxygen Species (ROS) in dengue infection and their correlations with clinical parameters (C4)
Mapalagamage MS, Handunnetti SM, Premawansa G, Loeb M, De Silva AD, Premawansa S.A study of the involvement of Reactive Nitrogen Species (RNS) and Reactive Oxygen Species (ROS) in dengue infection and their correlations with clinical parameters (C4). Proceedings of the 7th Biennial Sessions of the AISSL, 2nd September 2014, pp 32
Volatile compounds from the Ethanolic Extract of Dried flowers of Aegle marmelos (Beli mal)
Kumari KDKP, Handunnetti SM, Samarasinghe K and Suresh TS. Volatile compounds from the Ethanolic Extract of Dried flowers of Aegle marmelos (Beli mal). 1st International conference on Unani, Ayurveda, Siddha and Traditional Medicine. Institute of Indigenous Medicine University of Colombo, December 2013; pp 107
The stimulatory effect of the water extract of dried flowers of Aegle marmelos in healthy humans
Kumari KDKP, Samarasinghe, Handunnetti SM and Suresh TS. The stimulatory effect of the water extract of dried flowers of Aegle marmelos in healthy humans. Third Euro-India International Conference on Holistic Medicine. Kerala India, September 2013; pp 85-86
Rapid detection of severe leptospirosis using a simple cost-effective method
Fernando TRGN, Handunetti SM, Niloofa MJR, Fernando GTG, De Silva NL, Wijerathne PPB, Rodrigo C, Karunanayake L, Wickremesinghe H, Dikmadugoda N, Premawansa G, De Silva HJ, Wickremesinghe AR, Premawansa S, Rajapakse S. Rapid detection of severe leptospirosis using a simple cost-effective method. Proceedings of the 46th Annual Academic Sessions of the Ceylon College of Physicians, 12th September 2013; Abstract no. OP16, pp 53
Protective effect of methano/ dichloromethane extract of Artocarpus nobilis on rat mast cell degranulation in vitro
Rukshala BAD, Handunnetti SM, De Silve E D. Protective effect of methano/ dichloromethane extract of Artocarpus nobilis on rat mast cell degranulation in vitro. World Congress on Pharmaceutical Science & Chemical Technology (1st Anniversary Celebration of International Society for Nature & Health Care Inc, USA). Colombo, Sri Lanka. December 2013: pp 41
Organoleptic properties of different preparations of the water extract of dried flowers of A. marmelos (Belimal drink) and black tea in volunteer subjects
Kumari KDKP, HandunnettiS, SamarasingheK and SureshTS. Organoleptic properties of different preparations of the water extract of dried flowers of A. marmelos (Belimal drink) and black tea in volunteer subjects. World Congress on Pharmaceutical Science & Chemical Technology (1st Anniversary Celebration of International Society for Nature & Health Care Inc, USA). Colombo, Sri Lanka. December 2013: pp 38-39
ncreased oxidative stress in severe leptospirosis
Fernando TRGN, Niloofa MJR , De Silva NL, Fernando GTG, Wijerathne PPB, Rodrigo C, Wickremesinghe H, Dikmadugoda N, Premawansa G, Karunanayake L, De Silva H J, Rajapakse S, Premawansa S, Handunnetti SM. Increased oxidative stress in severe leptospirosis, Annual Research Symposium, University of Colombo, 4th October 2013; pp 177
Low serum total nitrite and nitrate levels in severe leptospirosis
Kalugalage TL, Rodrigo C, Vithanage T, Somaratne P, De Silva HJ, Handunnetti SM, Rajapakse S. Low serum total nitrite and nitrate levels in severe leptospirosis. BMC Infectious Diseases, 2013; 13-206
Low serum nitrite and anti-oxidant capacity in severe leptospirosis in Sri Lanka
Fernando TRGN, Niloofa MJR, Fernando GTG, De Silva NL, Rodrigo C, Karunanayake L,Wickremesinghe H, Dikmadugoda N, Premawansa G, De Silva HJ, Rajapakse S, Premawansa S, Handunetti SM.. Low serum nitrite and anti-oxidant capacity in severe leptospirosis in Sri Lanka. Proceedings of the 6thAnnual Scientific Sessions of the IBMBB, University of Colombo, 3rd May, 2013; pp 22
Low serum anti-oxidant capacity in severe leptospirosis patients in Sri Lanka
Fernando TRGN, Niloofa MJR, Fernando GTG, De Silva NL, Rodrigo C, Karunanayake L, Wickremesinghe H, Dikmadugoda N, Premawansa G, Wickremesinghe AR, De Silva HJ, Rajapakse S, Premawansa S, Handunetti SM. Low serum anti-oxidant capacity in severe leptospirosis patients in Sri Lanka. Proceedings of the 33rd Annual sessions of the IOB-SL, 27th September 2013; Abstract no. 3-14, pp 65
Laboratory confirmation of Leptospirosis: Comparison between microscopic agglutination test and IgM rapid test Leptocheck WB
Niloofa MJR, Fernando GTG, Fernando TRGN, Wolttan T, De Silva NL, Rodrigo C, Wickremesinghe H, Dikmadugoda N, Premawansa G, Karunanayake L, De Silva HJ, Premawansa S, Rajapakse S, Handunetti SM. Laboratory confirmation of Leptospirosis: Comparison between microscopic agglutination test and IgM rapid test Leptocheck WB. Proceedings of the 6thAnnual Scientific Sessions of the IBMBB, University of Colombo, 3rd May, 2013; pp 21
Involvement of serum reactive nitrogen species and reactive oxygen species in dengue patients in Sri Lanka
Mapalagamage MS, Handunnetti SM, Premawansa G, Loeb M, De Silva AD, Premawansa S. Involvement of serum reactive nitrogen species and reactive oxygen species in dengue patients in Sri Lanka. Proceedings of the 6th Annual Scientific Sessions of the IBMBB, University of Colombo, 3rd May, 2013; pp 35
Immunostimulatory activity of combined hot water extract of Coriandrum sativum L. and Coscinumfenstratum G. in rats
Edward D, Kothalawala SD, Handunnetti SM, Ratnasooriya WD, Premakumara GAS. Immunostimulatory activity of combined hot water extract of Coriandrum sativum L. and Coscinumfenstratum G. in rats. Proceedings of the 6th Annual Scientific Sessions of the IBMBB, University of Colombo, 3rd May, 2013; pp 34
Hypoglycemic mechanisms of the Beli- mal drink (water extract of dried flowers of Aegle marmelos)
Kumari KDKP, Handunnetti SM, Samarasinghe K and Suresh TS. Hypoglycemic mechanisms of the Beli- mal drink (water extract of dried flowers of Aegle marmelos) (104/A). Proceedings of the 69thAnnual Sessions of the SLAAS, 2013; pp 6
High serum nitrite levels as a prognostic marker for severe leptospirosis
Fernando TRGN, Rajapakse S, Premawansa S, De Silva HJ, Wickremesinghe AR, Handunnetti SM. High serum nitrite levels as a prognostic marker for severe leptospirosis. (914/A). Proceedings of the 69th Annual Sessions of the SLAAS, 2013; pp 211
High plasma TNF-a/IL-10 ratios are associated with severe P. falciparum malaria in Sri Lanka
Handunnetti S*, Perera M, Hearth N, Pathirana S, Mendis K, and Premawansa S. 2013. High plasma TNF-a/IL-10 ratios are associated with severe P. falciparum malaria in Sri Lanka (P3023). The Journal of Immunology, 2013, 190 (1001), 55. pp. 12. (http:// www.jimmunol.org/cgi/content/meeting_abstract/190/1MeetingAbstracts/55.12) [*Only the Abstract was published
Enhancement of antigen specific Immunoglobulin G and M following in vivo treatment of combined hot water extract of Corianderum sativum L. and Coscinumfenstratum G. in rats
Edward D, Premakumara GAS, Ratnasooriya WD, Handunnetti SM. Enhancement of antigen specific Immunoglobulin G and M following in vivo treatment of combined hot water extract of Corianderum sativum L. and Coscinumfenstratum G. in rats (414/D). Proceedings of the 69thAnnual Sessions of the SLAAS, 2013; pp 90
Effect of the water extract of dried flowers of Aegle marmelos on fasting serum glucose concentrations and glucose tolerance of healthy volunteers
Kumari KDKP, Handunnetti SM, Suresh TS and Samarasinghe K. Effect of the water extract of dried flowers of Aegle marmelos on fasting serum glucose concentrations and glucose tolerance of healthy volunteers. International Conference on Pharamacognosy, Phytochemistry and Natural Products. Hydrabad, India. October 2013: pp 61
Effect of reactive oxygen species on serum antioxidant capacity in dengue patients in Sri Lanka (913/A)
Mapalagamage MS, Handunnetti SM, Premawansa G, Loeb M, De Silva AD, Premawansa S. Effect of reactive oxygen species on serum antioxidant capacity in dengue patients in Sri Lanka (913/A). Proceedings of the 69th Annual Sessions of the SLAAS, 2013; pp 210
Determination of serum lipid peroxide and NOx level in severe leptospirosis patients in Sri Lanka
Wolttan T, Fernando GTG, Niloofa MJR, Rodrigo C, Wickremesinghe H, Dikmadugoda N, Karunanayake L, De Silva HJ, Premawansa S, Rajapakse S, Handunetti SM. Determination of serum lipid peroxide and NOx level in severe leptospirosis patients in Sri Lanka. Proceedings of the 6th Annual Scientific Sessions of the IBMBB, University of Colombo, 3rd May, 2013; pp 23
Comparison of the antioxidant activity of the water extract of dried flowers of A. marmelos with Black and Green tea
Kumari KDKP, Handunnetti S, Samarasinghe K and Suresh TS. Comparison of the antioxidant activity of the water extract of dried flowers of A. marmelos with Black and Green tea. World Congress on Pharmaceutical Science & Chemical Technology (1st Anniversary Celebration of International Society for Nature & Health Care Inc, USA) Colombo, December 2013; pp 38
Coagulation disorders in patients with leptospirosis
Threeswaran R, Gooneratne L, Handunnetti SM, Rajapakse S. Coagulation disorders in patients with leptospirosis (PP4). Proceedings of 7th Annual Scientific Sessions of the IBMBB, University of Colombo. 21st May 2015; pp 31
Association of high plasma TNF-α levels and TNF-α/ IL-10 ratios with TNF2 allele in severe P. falciparum malaria patients in Sri Lanka
Perera MK, Herath NP, Pathirana SL, Phone-Kyaw M, Alles HK, Mendis KN, Premawansa S, Handunnetti SM. Association of high plasma TNF-α levels and TNF-α/ IL-10 ratios with TNF2 allele in severe P. falciparum malaria patients in Sri Lanka. Pathogens & Global Health, 2013; 107:21-29
Anti-inflammatory activity of Pleurotus ostreatus mushroom in diabetic Wistar rats
Jayasuriya WJABN, Fernando GH, Wanigatunga CA, Handunnetti SM, Abeytunga T, Suresh S. Anti-inflammatory activity of Pleurotus ostreatus mushroom in diabetic Wistar rats. (102/A). Proceedings of the 69thAnnual Sessions of the SLAAS, 2013; pp 3
Anti- histamine ans Membrane stabilization activity and the effect on infiltration of rat peritoneal cells of the water extract of dried flowers of Aegle marmelos
Kumari KDKP, Handunnetti SM, Samarasinghe K and Suresh TS. Anti- histamine ans Membrane stabilization activity and the effect on infiltration of rat peritoneal cells of the water extract of dried flowers of Aegle marmelos. KDU International Research Symposium. Kothalawala Defense University Sri Lanka, 2013; pp 45
Ankyrin repeat domine 30 A (NY-BR-1) and Mammaglobin-B as markers for detection of micrometastasis of breast cancer
Muraleetharan S, De Silva WHYD, De Silva K, Jayasekera P, Goonesinghe R, Seneviratne B, Selvakumara R, Pathirana A, Weerasena OVDSJ, Handunnetti SM. Ankyrin repeat domine 30 A (NY-BR-1) and Mammaglobin-B as markers for detection of micrometastasis of breast cancer. Proceedings of the 6th Annual Scientific Sessions of the IBMBB, University of Colombo, 3rd May, 2013; pp 25
Trichosanthes cucumerina Linn: As a potential anti-inflammatory agent
Arawwawala LDAM, Thabrew MI, Arambawela LSR and Handunnetti SM. Trichosanthes cucumerina Linn: As a potential anti-inflammatory agent. Proceedings of the International Conference on Chemical Sciences, Colombo, Sri Lanka, 21st June, 2012: NP12, pp 24
The effect of the water extract of dried flowers of Aegle marmelos on production of nitric oxide by rat peritoneal cells.
Kumari KDKP, Handunnetti SM, Suresh TS and Samarasinghe K. The effect of the water extract of dried flowers of Aegle marmelos on production of nitric oxide by rat peritoneal cells. 4th International Conference on Medicinal Plants and Herbal Products. John Hopkins University Montgomery Country Campus Rockville, MD, USA, September 2012; pp 31
Strain-specific protective effect of the immunity induced by live malarial sporozoites under chloroquine cover
Wijayalath W, Cheesman S, Tanabe K, Handunnetti S, Carter R, Pathiarana S. Strain-specific protective effect of the immunity induced by live malarial sporozoites under chloroquine cover. PLoS ONE, 2012; 7(9): e45861. doi:10.1371/journal.pone.0045861
Serum nitrite levels in Sri Lankan patients with Leptospirosis
Gunaratna RT, Handunnetti SM, Bulathsinghalage MRC, Somaratne P, Jayanaga A, De Silva HJ, Rajapakse S. Serum nitrite levels in Sri Lankan patients with Leptospirosis. Asian Pacific Journal of Tropical Medicine, 2012; 75-78